Cow’s milk protects against HIV

Marut

Cow, Gau, Milk

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Ideally, you want to prevent the AIDS virus from entering the body in the first place, so it would be best to somehow make the Trojan horse strategy impossible for HIV.

In prevention, Lactoferrin plays vital role. Lactoferrin (LF), also known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family. Lactoferrin is Nature’s Premier Immune-Boosting Protein.Human colostrum (“first milk”) has the highest concentration, followed by human milk, then cow milk (150 mg/L).

Potent antiviral effects have been described for lactoferrin. Human cytomegalovirus, human herpes simplex virus-1, and human immunodeficiency virus (HIV, the virus responsible for AIDS) all have been inhibited by lactoferrin in laboratory experiments. Viral infections are believed to be involved in the etiology of certain types of leukemia. In an experimental model in which mice are infected with a virus that produces conditions similar to leukemia, mice given lactoferrin fared significantly better than control mice in terms of the degree of illness.

We discussed lactoferrin here: http://prachodayat.in/lactoferrin-cow-milk/

Those children are real healthwise unfortunate whose mothers could not naturally lactate. They miss real nectar in form of mother’s love, her colostrum.

For a healthy Citizen, promote the message! Mothers must must feed their milk to children! Once their lactation cycle is over, switch to desi indigenous Gau-milk.

Here is another study glorifying Cow milk value in our life.


Research News


Cow’s milk protects against HIV

Melbourne researchers have developed cows’ milk that protects human cells from HIV. The milk contains antibodies which defend against human immunodeficiency virus (HIV).

The next step will be to develop it into a cream which women can apply to protect themselves from contracting HIV from sexual partners.

Melbourne University’s Dr Marit Kramski and colleagues found that using cows to produce HIV-inhibiting antibodies is cheaper than existing methods.

They worked with Australian biotechnology company Immuron Ltd to develop the milk. The scientists vaccinated pregnant cows with an HIV protein and studied the first milk that cows produced after giving birth.

The first milk, called the colostrum, is naturally packed with antibodies to protect the newborn calf from infections. The vaccinated cows produced HIV antibodies in their milk.

“We were able to harvest antibodies specific to the HIV surface protein from the milk,” said Marit, who is presenting her research this week as one of the winners of Fresh Science — a national program for early-career scientists.

http://www.sciencealert.com/milk-protects-cells-against-hiv


Research Papers


Hyperimmune bovine colostrum as a low-cost, large-scale source of antibodies with broad neutralizing activity for HIV-1 Envelope with potential use in microbicides.

Bovine colostrum (first milk) contains very high concentrations of IgG and on average 1 kg (500 g/L) of IgG can be harvested from each immunized cow immediately after calving. We used a modified vaccination strategy together with established production systems from the dairy-food industry for the large-scale manufacture of broadly neutralizing HIV-1 IgG. This approach provides a low-cost mucosal HIV preventive agent potentially suitable for a topical microbicide. Four cows were vaccinated pre- and/or post-conception with recombinant HIV-1 gp140 envelope (Env) oligomers of clade B or A, B and C. Colostrum and purified-colostrum IgG were assessed for cross-clade binding and neutralization against a panel of 27 Env-pseudotyped reporter viruses. Vaccination elicited high anti-gp140 IgG titers in serum and colostrum with reciprocal endpoint titers of up to 1×105. While non-immune colostrum showed some intrinsic neutralizing activity, colostrum from 2 cows receiving a longer duration vaccination regimen demonstrated broad HIV-1 neutralizing activity. Colostrum-purified polyclonal IgG retained gp140-reactivity and neutralization activity and blocked the binding of the b12 monoclonal antibody to gp140, showing specificity for the CD4 binding site. Colostrum derived anti-HIV antibodies offer a cost-effective option for preparing the substantial quantities of broadly neutralizing antibodies that would be needed in a low-cost topical combination HIV-1 microbicide.

http://aac.asm.org/content/early/2012/05/30/AAC.00453-12.abstract

Lactoferrin

Infants receive valuable assistance from their mothers breast milk to combat infection and disease during the critical neonatal period when their immune systems are not yet fully functional. While breast milk contains a myriad of biologically active molecules, one in particular, lactoferrin, has recently received extensive attention from research scientists, health practitioners, and the general public.

Why all the interest? Well, to begin with, anecdotal evidence of healing attributed to lactoferrin when taken as a nutritional supplement is plentiful. Some accounts with respect to cancer, immune deficiency and other afflictions are described as nothing short of miraculous. From a more scientific perspective, basic research on the molecular, cellular, and physiological properties of lactoferrin has increased tremendously in the past few years as the results of each new study generate further interest and excitement. So great is the promise of this protein  discovered over 30 years ago  that research is being encouraged by the National Institutes of Health. Here, I describe biological characteristics and properties of lactoferrin as revealed in recent scientific studies and include a sampling of the therapeutic miracles attributed to it.

 

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