Bharatiya mind accepted sleep as essential medicine 5000 years back.
त्रय उपस्तम्भा: आहार: स्वप्नो ब्रह्मचर्यमिति (चरक संहिता सूत्र. 11/35)
अर्थात् शरीर और स्वास्थ्य को स्थिर, सुदृढ़ और उत्तम बनाये रखने के लिए आहार, स्वप्न (निद्रा) और ब्रह्मचर्य – ये तीन उपस्तम्भ हैं। ‘उप’ यानी सहायक और ‘स्तम्भ’ यानी खम्भा। इन तीनों उप स्तम्भों का यथा विधि सेवन करने से ही शरीर और स्वास्थ्य की रक्षा होती है।
Are we not living terribly anti-life routine? Do you love your life? your family? If yes, act.
Isn’t it a heinous crime to waste human life? Yes, it is terrible crime. It is called प्रज्ञापराध.
Research
To Sleep, Perchance to Heal: A Newly Discovered Gene Governs the Need for Slumber When Sick
Penn Study of Fruit Flies Finds a Direct Link Between Illness and the Need for More Sleep
https://www.pennmedicine.org/news/news-releases/2019/january/to-sleep-perchance-to-heal-a-newly-discovered-gene-governs-the-need-for-slumber-when-sick
Humans spend nearly one-third of their lives in slumber, yet sleep is still one of biology’s most enduring mysteries. Little is known about what genetic or molecular forces drive the need to sleep—until now. In a study of over 12,000 lines of fruit flies, researchers from the Perelman School of Medicine at the University of Pennsylvania have found a single gene, called nemuri, that increases the need for sleep. These findings are published today in Science.
The NEMURI protein fights germs with its inherent antimicrobial activity and it is secreted by cells in the brain to drive prolonged, deep sleep after an infection.
“While it’s a common notion that sleep and healing are tightly related, our study directly links sleep to the immune system and provides a potential explanation for how sleep increases during sickness,” said senior author Amita Sehgal, PhD, a professor of Neuroscience and director of Penn’s Chronobiology Program.
Without the nemuri gene, flies were more easily aroused during daily sleep, and their acute need for an increase in sleep—induced by sleep deprivation or infection—was reduced. On the other hand, sleep deprivation, which increases the need for sleep, and to some extent infection, stimulated nemuri to be expressed in a small set of fly neurons nestled close to a known sleep-promoting structure in the brain. Overexpression of nemuri increased sleep in bacteria-infected flies and led to their increased survival compared to non-infected control flies.
