Pain-killer drugs invite deadly infection

Marut

Infection, Microbes, Painkillers

painkillers

We need to understand one thing for sure. Modern medicines don’t really provide cure but hide the symptoms. In efforts of hiding the symptoms, it creates more issues for body by disturbing energy system(प्राणमय कोष). It hampers body’s natural healing tendency. Develop तितिक्षा (सरदी,गरमी आदि सहन करने की शारीरिक शक्ति। ,.कष्ट,दुख आदि झेलने का सामर्थ्य। ) and wait for body to heal itself. Modern medicines are only for emergencies.


Research


https://www.asm.org/Press-Releases/How-Common-Pain-Relievers-May-Promote-Clostridium

How Common Pain Relievers May Promote Clostridium difficile Infections

Clostridium difficile causes the most common and most dangerous hospital-born infections in the United States and around the world. People treated with antibiotics are at heightened risk because those drugs disturb the microbial balance of the gut, but observational studies have also identified a link between severe C. difficile infections and use of NSAIDs, or non-steroidal anti-inflammatory drugs. The study is published in the journal, mBio.

Findings published this week provide new evidence for that connection, as well as an explanation of the underlying biological mechanism. A better understanding of how NSAIDs affect the severity of C. difficile infection could inform the development of future treatments.

“We are always trying to think of modifiable risk factors for the disease,” says study leader David Aronoff, a microbiologist and infectious diseases expert at Vanderbilt University in Nashville, Tennessee. Aronoff worked on the study with researchers from the University of Michigan and the University of Arizona.

The researchers followed two groups of antibiotic-treated mice for one week after infection with C. difficile. One group had been treated with an NSAID called indomethacin prior to infection, and the other hadn’t. Only about 20 percent of the mice treated with the NSAID survived to the end of the observation period, compared to about 80 percent of the mice that hadn’t been exposed to the NSAID.

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