Sleep

Sleep

Three Pillars of Life

0

त्रय उपस्तम्भा: आहार: स्वप्नो ब्रह्मचर्यमिति (चरक संहिता सूत्र. 11/35)

threepillars
अर्थात् शरीर और स्वास्थ्य को स्थिर, सुदृढ़ और उत्तम बनाये रखने के लिए आहार, स्वप्न (निद्रा) और ब्रह्मचर्य – ये तीन उपस्तम्भ हैं। ‘उप’ यानी सहायक और ‘स्तम्भ’ यानी खम्भा। इन तीनों उप स्तम्भों का यथा विधि सेवन करने से ही शरीर और स्वास्थ्य की रक्षा होती है।

Are we not living terribly anti-life routine? Do you love your life? your family? If yes, act.

Isn’t it a heinous crime to waste human life? Yes, it is terrible crime. It is called प्रज्ञापराध.

धी धृति स्मृति विभ्रष्ट: कर्मयत् कुरुतऽशुभम्।
प्रज्ञापराधं तं विद्यातं सर्वदोष प्रकोपणम्।। — (चरक संहिता; शरीर. 1/102)

अर्थात् धी (बुद्धि), धृति (धैर्य) और स्मृति (स्मरण शक्ति) के भ्रष्ट हो जाने पर मनुष्य जब अशुभ कर्म करता है तब सभी शारीरिक और मानसिक दोष प्रकुपित हो जाते हैं। इन अशुभ कर्मों को प्रज्ञापराध कहा जाता है। जो प्रज्ञापराध करेगा उसके शरीर और स्वास्थ्य की हानि होगी और वह रोगग्रस्त हो ही जाएगा।

If there is sickness, man would jump between sleep and food, try to correct them, but will hardly pay attention to Brahmcharya :). Such is the shoddy state of our modern living. Think about it.

Psychological stress, Ama (Toxins) and Aging

0

I receive many queries related to premature aging. Reduced appetite, reduced sleep, grey hair, arthritis – All these issues manifest after 40. But you now see them even in age below 20.

stress

In old age, we can understand, it is due to मन्दाग्नि (Mandagni – Low Fire) but how come they are now regular in young age?

Ama (आम) – Toxins – Something that is unripe. Unripe outcomes of biological process. it can be at the time of digestion, assimilation or purging. All three stages or any one of them, when not working as per laws of the body, accumulates toxins locally. That is आम.

These end products, being inadequately processed, have a macromolecular structure, which is bigger and grosser than those end products which might have produced if a complete processing would have taken place.

It happens naturally in old-age. It happens unnaturally in young age due to following habits:

Despite physically young and metabolically active, if you indulge in physical and mental activities just after having meal, you are disturbing active digestion process. This can result in Ama i.e. Toxins.

Irregular meal timings is another reason that disturbs fire-based processes in body.

Regular intake of food lacking hydration and fat (dry), cold food, stale food can also generate Ama.

Too many emotions out of balance. Extreme Kama, Krdha, Lobha, Moha, Irshya. Extreme lajja, shoka, abhimana, Udvega, Bhaya, Up-tapta (sad).

In many experimental studies, various types of physical and psychological stress are found to induce dysfunction of intestinal barrier, resulting in enhanced intake of potentially noxious material (e.g., antigens, toxins, and other proinflammatory molecule) from the gut lumen into the bloodstream [1] . This gives a very interesting proposition to see if these noxious materials play the role of ama as a progenitor to joint diseases as perceived in Ayurveda.

In short, Quality of the food + Intake method and timing + Mood + Compatibility with your nature and age play critical role in perfect digestion, assimilation and elimination.

Check your routine. Check life of avg urban teen-ager. You will realize reason behind early aging. If such habits continue for 3-4 generations, rapid aging becomes स्वभाव of the gene-pool.

Take care. Check your habits in mirror. Correct them. Whatever happened so far, cannot be reversed but you can certainly slow down further aging by eliminating toxins and not making their way again in the body.


Research


[1]

[1] Stress and intestinal barrier function

http://ajpgi.physiology.org/content/280/1/G7

The intestinal mucosa is continuously exposed to an immense load of antigens from ingested food, resident bacteria, invading viruses, etc. The single-cell epithelial layer lining the gut lumen (surface area ∼300 m2) has conflicting functions, playing a major role in the digestion and absorption of nutrients and at the same time constituting the organism’s most important barrier between the internal and external environments. Under normal circumstances, the epithelium allows only minute quantities of intact antigens to cross into the mucosa, where they interact with the mucosal immune system to downregulate inflammation (known as oral tolerance). On the other hand, it is necessary for enteric pathogens to activate immune cells and initiate the inflammatory response required to clear the infection. In some disease conditions, such as inflammatory bowel disease, excessive penetration of antigens through the epithelial layer may result in inappropriate immune stimulation, leading to chronic gastrointestinal inflammation. The ability of the epithelium to control uptake of molecules into the body is denoted as the intestinal barrier function.

 

Vitamin B12 Deficiency, GUT and Muladhara

3

Yesterday was harsh day of this season. Heavy rain, humid, and extreme heat. My friend and I, working on critical task, felt exhausted. Dehydrated.

Friend suggested :”I think it is again Vitamin B12 deficiency! I think I will need injections again!”

I wondered. How a simple season driven exhaustion is turned into deficiency! 🙁

There were two things at play for both of us. 1) Stress induced non-healthy GUT 2) lack of healthy food for days.

Solution is to take rest. Worship Ganesha and eat healthy season driven food!

 

B12 Eyewash
B12 Eyewash

Modern medicine has reduced wholesome food into supplement status symbols.

Oh, B12 ? Take injections!
Oh Vit A? Take this supplement!

This is nothing but eyewash. Unless we correct our GUT, there is no hope for malnutrition.Malnutrition may manifest as either obesity or undernutrition. Accumulating evidence suggests that the gut microbiota plays an important role in the harvest, storage, and expenditure of energy obtained from the diet.

Gut Health
Gut Health

One person might have stronger nerves than another because she has a better stock of vitamin B–producing bacteria. Another person might be able to deal easily with bit of bread mold eaten by mistake. Yet another might have a tendency to gain weight because the “chubby” bacteria in his gut feed him a bit too willingly. Science is just beginning to understand that each of us is an entire ecosystem.

You take all costly B-12 injections or Vitamin A supplement or Vitamin C but if your GUT is not healthy, they are garbage and will be purged within 72 hrs via urine and stool!

There is no shortcut for healthy life. Stop nonsensical torture on body first. Stop all processed acidic food so that bacteria have chance to get flourished in you GUT. Then stop stressful events in life. Late night parties, tongue-lust driven non-seasonal food – stop it if you really want your B12 injections to work.

Above all physical nutrition, health is all mental. To correct your mental stress and linked sick GUT, this is best season. गणपति is protector of GUT. As per Tantra-Shashtra, गणपति lives in Muladhara, an energy center near GUT. It is your mind that helps प्राणमय शरीर (cellular intelligence) to form health अन्नमय शरीर (physical body) (Do not ask proof. Modern proof-based science cannot swim in this sea of knowledge at this moment). Experiment! Does not matter if you are an atheist! Or follow any other religion. गणपति is eternal, beyond religious boundaries.

Worship and surrender to गणपति. That is the beginning of the yearly healthy GUT.

ॐ गणेशाय नमः |

Muladhara Protector
Muladhara Protector

Research


Bacteria as vitamin suppliers to their host: a gut microbiota perspective.

http://www.ncbi.nlm.nih.gov/pubmed/22940212

Food-related lactic acid bacteria (LAB) as well as human gut commensals such as bifidobacteria can de novo synthesize and supply vitamins. This is important since humans lack the biosynthetic capacity for most vitamins and these must thus be provided exogenously. Although vitamins are present in a variety of foods, deficiencies still occur, mainly due to malnutrition as a result of insufficient food intake and because of poor eating habits. Fermented milks with high levels of B-group vitamins (such as folate and riboflavin) can be produced by LAB-promoted and possibly bifidobacteria-promoted biosynthesis. Moreover, certain strains of LAB produce the complex vitamin cobalamin (or vitamin B12). In this review, fermented foods with elevated levels of B-group vitamins produced by LAB used as starter cultures will be covered. In addition, genetic abilities for vitamin biosynthesis by selected human gut commensals will be discussed.

Vitamin B12 synthesis by human small intestinal bacteria.

http://www.ncbi.nlm.nih.gov/pubmed/7354869

In man, physiological amounts of vitamin B12 (cyanocobalamin) are absorbed by the intrinsic factor mediated mechanism exclusively in the ileum. Human faeces contain appreciable quantities of vitamin B12 or vitamin B12-like material presumably produced by bacteria in the colon, but this is unavailable to the non-coprophagic individual. However, the human small intestine also often harbours a considerable microflora and this is even more extensive in apparently healthy southern Indian subjects. We now show that at least two groups of organisms in the small bowel, Pseudomonas and Klebsiella sp., may synthesise significant amounts of the vitamin.

Effects of Gut Microbes on Nutrient Absorption and Energy Regulation

Malnutrition may manifest as either obesity or undernutrition. Accumulating evidence suggests that the gut microbiota plays an important role in the harvest, storage, and expenditure of energy obtained from the diet. The composition of the gut microbiota has been shown to differ between lean and obese humans and mice; however, the specific roles that individual gut microbes play in energy harvest remain uncertain. The gut microbiota may also influence the development of conditions characterized by chronic low-level inflammation, such as obesity, through systemic exposure to bacterial lipopolysaccharide derived from the gut microbiota. In this review, the role of the gut microbiota in energy harvest and fat storage is explored, as well as differences in the microbiota in obesity and undernutrition.

 

Research: Not just enough sleep, timely sleep!

0

We have saying: Those who sleep early and wake up early, are Heroes. They receive strength, intellect, knowledge and wealth. Their body remains in bliss.

But our so called educated and rational flock make fun of it and says: If this is true, all milkmen and newspaper vendors should be wealthy!

Claps! Good joke! 😀

What you miss in this silly argument is noteworthy.

Shifting sleep cycle affects immune response, sleep quality

Late? Forever
Late? Forever

Ayurveda


ब्राह्मे मुहूर्ते बुध्येत स्वस्थो रक्षाऽथमायुषः|

तत्र सर्वाघशान्त्यर्थं स्मरेद्धि मधुसूदनम्||

अर्थात् स्वस्थ व्यक्ति को अपनी जीवन-रक्षा के लिए प्रातः काल ब्रह्ममुहूर्त में उठना चाहिए।

Those who want to protect life, should wake up in the early morning (4 AM) and spend time in self-realization.

ब्राह्मे मुहूर्त उत्तिष्ठेतस्वस्थो रक्षार्थमायुष : ।

Brahm muhurt = 96 minutes before sunrise. Adjust your routine accordingly.

ब्राह्मे मुहूर्ते बुध्येत धर्मार्थांचानुचिंतयेत।

कायक्लेषाँष्च तन्मूलान्वेदतत्तवार्थमेव च॥ (मनु. 4/92)

प्रत्येक मनुष्य को ब्रह्ममुहूर्त में उठकर धर्म और अर्थ का चिंतन करना तथा शरीर के रोग और उनके कारणों का विचार करना एवं वेद के रहस्यों का भी विचार-चिंतन करना चाहिए।

What do we have now?

Everyday different wake up time. Mostly after sunrise. 🙂 Job forces to alter sleep as per shift!

Dincharya
Dincharya

Read this research.


Research


Shifting sleep cycle affects sleep quality, immune response

Shifting sleep cycle affects sleep quality, immune response

Most sleep research focuses on the effects of sleep deprivation or the overall amount of sleep an animal needs. This is generally referred to as sleep’s homeostatic process, which is driven by sleepiness or “sleep pressure.”

The work by Karatsoreos and his colleagues – published in the journal Brain, Behavior and Immunity – is a rare look into the circadian process, a brain-driven clock that controls the rhythms of various biological processes, from digestion to blood pressure, heart rate to waking and sleeping. The cycle is found in most everything that lives more than 24 hours, including plants and single-celled organisms.

Research into the system has significant implications for modern living, write Karatsoreos and his coauthors, as “disruption of the circadian clock is nearly ubiquitous in our modern society” due to nighttime lighting, shift work, jet lag and even the blue-tinged light emitted by cell phones and tablets.

Typically, sleep researchers have a hard time studying sleep deprivation and the circadian cycle separately, as a change in one usually affects the other. However, Karatsoreos and his colleagues saw their model did not affect an animal’s total sleep, giving them a unique look into the effects on the timing of the sleeping-waking cycle.

The researchers used mice whose body clocks run at about 24 hours – much like our own – and housed them in a shorter 20-hour day. This forced their biological clocks out of sync with the light-dark cycle. After four weeks, the researchers injected the mice with lipopolysaccharide, a molecule found in bacteria that can make an animal sick without being contagious.

Environmental disruption of the circadian clock leads to altered sleep and immune responses in mouse

In mammals, one of the most salient outputs of the circadian (daily) clock is the timing of the sleep–wake cycle. Modern industrialized society has led to a fundamental breakdown in the relationship between our endogenous timekeeping systems and the solar day, disrupting normal circadian rhythms. We have argued that disrupted circadian rhythms could lead to changes in allostatic load, and the capacity of organisms to respond to other environmental challenges. In this set of studies, we apply a model of circadian disruption characterized in our lab in which mice are housed in a 20 h long day, with 10 h of light and 10 h of darkness. We explored the effects of this environmental disruption on sleep patterns, to establish if this model results in marked sleep deprivation. Given the interaction between circadian, sleep, and immune systems, we further probed if our model of circadian disruption also alters the innate immune response to peripheral bacterial endotoxin challenge. Our results demonstrate that this model of circadian disruption does not lead to marked sleep deprivation, but instead affects the timing and quality of sleep. We also show that while circadian disruption does not lead to basal changes in the immune markers we explored, the immune response is affected, both in the brain and the periphery. Together, our findings further strengthen the important role of the circadian timing system in sleep regulation and immune responses, and provide evidence that disrupting the circadian clock increases vulnerability to further environmental stressors, including immunological challenges.

http://www.sciencedirect.com/science/article/pii/S0889159114005716

Coffee Culture, Teens, Sleep And Cultural Alienation

0

We now take pride in coffee culture while it is not even our native drink! 😀 Such level of sheepish mentality prevails in our society. Imitate west blindly!

See what happens when this addiction succumbs you in early teen age.

Vicious cycle of insensitive generations
Vicious cycle of insensitive generations

Research


Adolescents Living the 24/7 Lifestyle: Effects of Caffeine and Technology on Sleep Duration and Daytime Functioning

http://pediatrics.aappublications.org/content/123/6/e1005?sso=1&sso_redirect_count=1&nfstatus=401&nftoken=00000000-0000-0000-0000-000000000000&nfstatusdescription=ERROR%3a+No+local+token

OBJECTIVE. Adolescents may not receive the sleep they need. New media technology and new, popular energy drinks may be implicated in sleep deficits. In this pilot study we quantified nighttime technology use and caffeine consumption to determine effects on sleep duration and daytime behaviors in adolescents. We hypothesized that with increased technology use, adolescents increase caffeine consumption, resulting in insufficient sleep duration.

PATIENTS AND METHODS. Subjects were recruited from a pediatric office in a proximal suburb of Philadelphia, Pennsylvania. Inclusion criteria for this study were middle and high school subjects aged 12 to 18 years old. The questionnaire, Adolescent Sleep, Caffeine Intake, and Technology Use, was developed by the investigators to measure adolescents’ intake of caffeinated drinks, use of nighttime media-related technology, and sleep behaviors. Descriptive statistics characterized the subjects, their caffeine and technology use, and sleep variables. Regression models assessed the relationships between caffeine, technology use, and sleep variables, having adjusted for age, race, gender, and BMI.

RESULTS. Sleep was significantly related to the multitasking index. Teenagers getting 8 to 10 hours of sleep on school nights tended to have 1.5- to 2-fold lower multitasking indices compared with those getting less sleep. Thirty-three percent of the teenagers reported falling asleep during school. Caffeine consumption tended to be 76% higher by those who fell asleep. The log-transformed multitasking index was significantly related to falling asleep during school and with difficulties falling asleep on weeknights.

CONCLUSIONS. Many adolescents used multiple forms of technology late into the night and concurrently consumed caffeinated beverages. Subsequently, their ability to stay alert and fully functional throughout the day was impaired by excessive daytime sleepiness. Future studies should measure more than television hours when evaluating the impact of nighttime activities on sleep patterns in adolescents.

Gastrointestinal Disorders Are Associated Significantly With Sleepless Nights

https://www.sciencedaily.com/releases/2004/12/041220024853.htm

“We think the findings will generate further research to understand the interactions between emotional or psychological distress and sleep disturbances and GI disturbances,” says Santhi Swaroop Vege, M.D., a Mayo Clinic physician and lead author of the study.

Sleep disturbances and inflammatory bowel disease: a potential trigger for disease flare?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046047/

Inflammatory bowel disease (IBD) is a waxing and waning disease characterized by diarrhea, abdominal pain and weight loss. Recently, there has been an increased interest in the roles that sleep, circadian rhythms and melatonin could have as regulators of inflammation in the Gl tract. Advances in our understanding of the molecular machinery of the circadian clock, and the discovery of clock genes in the GI tract are opening up new avenues of research for a role of sleep in IBD. Altering circadian rhythm significantly worsens the development of colitis in animal models, and preliminary human studies have shown that patients with IBD are at increased risk for altered sleep patterns. Further research is needed to clarify the role of disturbances in IBD.

Sleep, immunity and inflammation in gastrointestinal disorders

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882397/

Sleep disorders have become a global issue, and discovering their causes and consequences are the focus of many research endeavors. An estimated 70 million Americans suffer from some form of sleep disorder. Certain sleep disorders have been shown to cause neurocognitive impairment such as decreased cognitive ability, slower response times and performance detriments. Recent research suggests that individuals with sleep abnormalities are also at greater risk of serious adverse health, economic consequences, and most importantly increased all-cause mortality. Several research studies support the associations among sleep, immune function and inflammation. Here, we review the current research linking sleep, immune function, and gastrointestinal diseases and discuss the interdependent relationship between sleep and these gastrointestinal disorders. Different physiologic processes including immune system and inflammatory cytokines help regulate the sleep. The inflammatory cytokines such as tumor necrosis factor, interleukin-1 (IL-1), and IL-6 have been shown to be a significant contributor of sleep disturbances. On the other hand, sleep disturbances such as sleep deprivation have been shown to up regulate these inflammatory cytokines. Alterations in these cytokine levels have been demonstrated in certain gastrointestinal diseases such as inflammatory bowel disease, gastro-esophageal reflux, liver disorders and colorectal cancer. In turn, abnormal sleep brought on by these diseases is shown to contribute to the severity of these same gastrointestinal diseases. Knowledge of these relationships will allow gastroenterologists a great opportunity to enhance the care of their patients.

BODY POSTURE DURING SLEEP : Cleaning waste

0
Sleeping Krishna
Sleeping Krishna
Lord Vishnu At Rest
Lord Vishnu At Rest
Bal Krishna at rest in lateral position
Bal Krishna at rest in lateral position

The brain’s glymphatic pathway clears harmful wastes, especially during sleep. This lateral position could prove to be the best position for the brain-waste clearance process.

======================

In our local culture (which many of my educated friends with being modern arrogance consider primitive), the word is वामकुक्षी. Sleeping on the left side.

======================

Thanks to our hyper-modern life, we hardly rest in this position after afternoon meal. So toxins level in body builds up. For some, they invite infection, for others, it becomes clog in the artery…and the sickness saga continues.

Respect local cultural habits. Follow them blindly! 🙂 Keep aside your being-educated arrogance.


Research


Sleeping in later position: Image Credit : stonybrook.edu
Sleeping in later position: Image Credit : stonybrook.edu

COULD BODY POSTURE DURING SLEEP AFFECT HOW YOUR BRAIN CLEARS WASTE?

Sleeping in the lateral, or side position, as compared to sleeping on one’s back or stomach, may more effectively remove brain waste and prove to be an important practice to help reduce the chances of developing Alzheimer’s, Parkinson’s and other neurological diseases, according to researchers at Stony Brook University.

“The analysis showed us consistently that glymphatic transport was most efficient in the lateral position when compared to the supine or prone positions,” said Dr. Benveniste. “Because of this finding, we propose that the body posture and sleep quality should be considered when standardizing future diagnostic imaging procedures to assess CSF-ISF transport in humans and therefore the assessment of the clearance of damaging brain proteins that may contribute to or cause brain diseases.”

http://sb.cc.stonybrook.edu/news/general/150804sleeping.php?=marquee2

Popular Posts

My Favorites

राष्ट्र भावना – अदृश्य प्रगाढ़ सूत्र

वयं राष्ट्रे जागृयाम पुरोहिता | यजु. राष्ट्र को बुराइयों से बचाये रखने का उत्तरदायित्व पुरोहितों का है। ----------------------- तमेव ऋषिं तमु ब्रह्माणमाहुर्यज्ञन्य सामगा | ऋग् १०/१०७/६ निरन्तर ज्ञान...