दीपावलीपे घर सफाई क्यूँ? Your Toxic Home Dust is Making you Fat

Marut

Environment, Epigenetics

Dust
Dust

I have discussed ample times that toxic chemicals and toxic oil painted walls are invisible demons at home. We are very unique humans who pay for the demons and invite them at home!!

We ignore Go dhuli (गोरज & गोधूलि बेला : Medicinal Dust) and raise questions on it! Can dust have impact on health? With this ignorance, we also invite toxic volatile chemicals at home and consume toxic dust!! 🙁

http://pubs.acs.org/doi/abs/10.1021/acs.est.7b01788
http://pubs.acs.org/doi/abs/10.1021/acs.est.7b01788

In this post, we discussed how Volatile organic compounds play against the health and how annual cleaning ritual during Diwali helps to reduce the impact (Deepawali Churning : Home Cleaning, lime wash and Immunity)

We also discussed how Vastu plays important role in maintaining healthy environment. (Microbes, Vastu and Pro-कल्याण Architecture)

Sun Rays in home is very critical to sanitize dust particles.

All Dharma Sastra(s) prescribes cleanliness of home as mandatory ritual.


Research


Characterization of Adipogenic Activity of House Dust Extracts and Semi-Volatile Indoor Contaminants in 3T3-L1 Cells

House dust spurs growth of fat cells in lab tests

Obesity and metabolic disorders are of great societal concern and generate significant human health care costs. Recently, attention has focused on the potential for environmental contaminants to act as metabolic disruptors. This study sought to evaluate the adipogenic activity of indoor house dust extracts and a suite of semivolatile organic chemicals (SVOCs) that are often ubiquitously detected in indoor environments. 3T3-L1 cells were exposed to extracts of indoor dust or individual SVOCs and assessed for triglyceride accumulation and preadipocyte proliferation. Ten of 11 house dust extracts exhibited significant triglyceride accumulation and/or proliferation at environmentally relevant levels (<20 μg of dust/well), and significant adipogenic activity was also exhibited by 28 of the SVOCs. Notably, pyraclostrobin, dibutyl phthalate, tert-butyl-phenyl diphenyl phosphate, and the isopropylated triaryl phosphates (ITPs) exhibited near maximal or supra-maximal triglyceride accumulation relative to the rosiglitazone-induced maximum. The adipogenic activity in house dust occurred at concentrations below EPA estimated child exposure levels, and raises concerns for human health impacts, particularly in children. Our results delineate a novel potential health threat and identify putative causative SVOCs that are likely contributing to this activity.

http://pubs.acs.org/doi/abs/10.1021/acs.est.7b01788

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