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Anogenital distance (AGD) is the distance from the anus to the genitalia, the base of the penis or vagina.

Phthalates are a group of chemicals used to make plastics more flexible and harder to break. They are often called plasticizers. Some phthalates are used as solvents (dissolving agents) for other materials. They are often part of food packaging material.

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Prenatal phthalate exposure impairs testicular function and shortens anogenital distance (AGD) in male.The median concentrations of phthalate metabolites that are associated with short AGI and incomplete testicular descent are below those found in one-quarter of the female population of the United States, based on a nationwide sample. These data support the hypothesis that prenatal phthalate exposure at environmental levels can adversely affect male reproductive development in humans. Situation is worse in country like India where there are no regulations related to plastic quality.

Depopulation is not an overnight goal for rulers of the World Economy (You should judge who all I am talking about) . They want to make it natural process. Over the next 2-3 generations, we will see the effect.

plastic

Junk food/Furnitures/Cleaning agents with endocrine disrupters (i.e. estrogen) -> Decrease in Anogenital Distance among Male Infants (Distance between Anus and Penis) -> Infertility -> Natural depopulation

SAVE YOUR CHILD! Stay away from Junk food, plastic, furniture polish, oil paints etc.

1) Always cook and serve naturally grown food to kids. As much as possible. Don’t use plastic bottles, containers. No matter how good quality they are, leaching is unavoidable.

2) Keep Tulsi plants at home. Spend time with her daily. Train kids to folow you. Tulsi has potential to keep your body toxic-free.

3) Always spend free time in nature. Garden, farm (where no chemicals are used for farming), jungle, mountain, rive

4) Do Surya Namaskar daily,. Train kids to do same once they cross age 7-8

5) Keep children away from chemicals used in paints, polish and cleaning agents.

Decrease in Anogenital Distance among Male Infants with Prenatal Phthalate Exposure

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280349/

Prenatal phthalate exposure impairs testicular function and shortens anogenital distance (AGD) in male rodents. We present data from the first study to examine AGD and other genital measurements in relation to prenatal phthalate exposure in humans. A standardized measure of AGD was obtained in 134 boys 2–36 months of age. AGD was significantly correlated with penile volume (R = 0.27, p = 0.001) and the proportion of boys with incomplete testicular descent (R = 0.20, p = 0.02). We defined the anogenital index (AGI) as AGD divided by weight at examination [AGI = AGD/weight (mm/kg)] and calculated the age-adjusted AGI by regression analysis. We examined nine phthalate monoester metabolites, measured in prenatal urine samples, as predictors of age-adjusted AGI in regression and categorical analyses that included all participants with prenatal urine samples (n = 85). Urinary concentrations of four phthalate metabolites [monoethyl phthalate (MEP), mono-n-butyl phthalate (MBP), monobenzyl phthalate (MBzP), and monoisobutyl phthalate (MiBP)] were inversely related to AGI. After adjusting for age at examination, p-values for regression coefficients ranged from 0.007 to 0.097. Comparing boys with prenatal MBP concentration in the highest quartile with those in the lowest quartile, the odds ratio for a shorter than expected AGI was 10.2 (95% confidence interval, 2.5 to 42.2). The corresponding odds ratios for MEP, MBzP, and MiBP were 4.7, 3.8, and 9.1, respectively (all p-values < 0.05). We defined a summary phthalate score to quantify joint exposure to these four phthalate metabolites. The age-adjusted AGI decreased significantly with increasing phthalate score (p-value for slope = 0.009). The associations between male genital development and phthalate exposure seen here are consistent with the phthalate-related syndrome of incomplete virilization that has been reported in prenatally exposed rodents. The median concentrations of phthalate metabolites that are associated with short AGI and incomplete testicular descent are below those found in one-quarter of the female population of the United States, based on a nationwide sample. These data support the hypothesis that prenatal phthalate exposure at environmental levels can adversely affect male reproductive development in humans.

 

1 COMMENT

  1. “Keep Tulsi plants at home. Spend time with her daily. Train kids to folow you. Tulsi has potential to keep your body toxic-free. ” — Any reference for the tulasi helping with pthalate/xeno-estrogen detox ?

    by the way, don’t you think india has already got a population bomb ? Have you ever got stuck in a traffic jam in Bangalore ? :). I am sure if the census is done correctly, we have already surpassed china packed in such a small land. Drinking water is such a problem. Our country will implode within the next 20 years.

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