They shape out social behaviour
They shape out social behaviour IMAGE SOURCE:

General understanding about immunity is very naive based on the memes spread by modern science custodians in last 100 years. So far, it used to be function preventing us from unforeseen illnesses. Protecting us from pathogens. That is it, right?

It is high time we understand the roots of immunity.

Sanskrit word मुनि means anyone who is moved by inward impulses. Someone who is self-inspired. Someone who is performing duties intuitively.

Now let us understand Latin: Latin word Munis (early *moinis, moenis) has as its principal meaning someone who discharges his office/duty, somebody accomplishing a tasks also contained is the connotation present, gift. Related to it are im-munis (with its derivative im-munitas {immunity}, that is, the exemption from charge or duty.

So in our body, all active cells are Muni(s) or मुनि ((S). They are working as per self-inspiration based on cellular intelligence they carry from birth. Immunity is the process of retiring cells from their duties. Why do we need it?

We need it because their job is over. To maintain the integrity of the body, it is necessary to give them good bye. This process of good bye is a Immune response. This is called Innate immunity. Sometimes, when external conditions are not good, cells die prematurely or their processing is affected severely. So they broadcast messages for help or to alert others in cell community. We call it Viruses. Viruses are dead information. They are not मुनि. They are born to get uprooted once message is conveyed to other cells. We call it viral infection. When severe condition persists for cells, they die prematurely. We call it bacterial infection.

In short, integrity of organism is essential for Muni(s) or Body cell to perform tasks. To help them immune system perform immunity process.

So-called immune system knows which part of the body is self, and what is not-self. A self-marker or a suimarker is endowed to each self-element, an advantage not denied to an alien unit or cell present at the time of thymic maturation.

So when immunity is compromised (मुनि characteristic of us), it is trauma and stress for each individual cell/bacteria/देव/पितर participating in our existence! Summation of it, emerges as anti-social behaviour! And that is what this paper talks about!

At the same time, it is our social interactions as a child, that shapes our immunity (our sense of identifying self from rest).  And as immunity is strengthen, we become and remain social.


“The brain and the adaptive immune system were thought to be isolated from each other, and any immune activity in the brain was perceived as sign of a pathology. And now, not only are we showing that they are closely interacting, but some of our behavior traits might have evolved because of our immune response to pathogens,” explained Jonathan Kipnis, chair of UVA’s Department of Neuroscience. “It’s crazy, but maybe we are just multicellular battlefields for two ancient forces: pathogens and the immune system. Part of our personality may actually be dictated by the immune system.”

The UVA researchers have shown that a specific immune molecule, interferon gamma, seems to be critical for social behavior and that a variety of creatures, such as flies, zebrafish, mice and rats, activate interferon gamma responses when they are social. Normally, this molecule is produced by the immune system in response to bacteria, viruses or parasites. Blocking the molecule in mice using genetic modification made regions of the brain hyperactive, causing the mice to become less social. Restoring the molecule restored the brain connectivity and behavior to normal. In a paper outlining their findings, the researchers note the immune molecule plays a “profound role in maintaining proper social function.”


“It’s extremely critical for an organism to be social for the survival of the species. It’s important for foraging, sexual reproduction, gathering, hunting,” said Anthony J. Filiano, Hartwell postdoctoral fellow in the Kipnis lab and lead author of the study. “So the hypothesis is that when organisms come together, you have a higher propensity to spread infection. So you need to be social, but [in doing so] you have a higher chance of spreading pathogens. The idea is that interferon gamma, in evolution, has been used as a more efficient way to both boost social behavior while boosting an anti-pathogen response.”

Now, we see viruses, bacteria and mosquitos as our enemies. Think about it. Are they our enemies? Or they are mother nature’s faithful workers shaping our immunity! (self-realization! Moksha! What not! It starts with the physical self!)