Immune System Fosters Good Bacteria

Nisarg Joshi

GUT, Immunity, Microbes

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We have been taught that immune system means Army. Immune System is defense system. But we were never taught that the immune system does more than mere purging non-body particles out of body.

Here is the interesting finding which supports what we discussed on this subject recently:
“When the immune system functions properly (MyD88 is active, green), IgA antibodies bind multiple species of bacteria, keeping the numbers and types of ‘good’ bacteria that inhabit the gut under control. (Right) When the immune system is disrupted (MyD88 is inactive, gray), IgA binds bacteria less effectively, and the bacterial community becomes imbalanced, jeopardizing digestive health.”

If bacteria are enemy, why would immune system help them grow? 🙂

There is no enmity with Mother Nature as most brainwashing media tell you. There is no war against bacteria or Virus going on. Purpose of immune system is to maintain your existence. That is it.

The ability of the human body to live in peace with 10 microbes per every human cell is a state of genuine immunity, wherein the body exercises a holy indifference to the resident microbes, to gain therefrom freedom from any reactivity against the obviously non-self microbes.

This is ability to realize self and non-self can be best developed when a child is exposed more often to mother nature.

Stop this delusion of war against the nature and see the magic. Your life will be much more healthier then the past! Try it! (Y)

Tulsi, Turmeric, Ghee (Desi Gau’s), Honey (Pure jungle based), Milk (Desi gau’s raw) – they all help you too strengthen immune system i.e. your own identity so that your body can identify self from non-self! 🙂


Research


http://healthcare.utah.edu/publicaffairs/news/2015/01/01-22-15_Immune_System_Fosters_Good_Bacteria.php

Immune System Promotes Digestive Health by Fostering Community of “Good” Gut Bacteria

As many as 1.4 million Americans suffer from uncomfortable abdominal cramping and diarrhea that come with ulcerative colitis and Crohn’s disease. These conditions, collectively known as inflammatory bowel disease (IBD), are associated with an imbalance among the thousands of species of “good” bacteria that inhabit the gut. A University of Utah study published on Jan. 22, 2015, in Cell Host and Microbe demonstrates that mice deficient for a component of the immune system, a protein called MyD88, have an imbalanced gut bacterial community – with some species dominating over others – and are more susceptible to contracting a severe IBD-like illness. Further, fecal transplants from healthy donors alleviate IBD symptoms in these mice.

The results show that the immune system encourages growth of a healthy community of “good” bacteria that is important for digestive health. This perspective on immune system function is in contrast to it’s best-known role as the first line of defense in the fight against pathogens, including invasive bacteria.

“Our work highlights that the immune system shapes the composition of bacterial communities in the intestine,” says senior author June Round, Ph.D., assistant professor of pathology at the University of Utah School of Medicine. “This interaction is important because it’s becoming more and more clear that resident microbes are very important for our health.”

Considering that some people with IBD have mutations in genes that are part of a MyD88-controlled pathway, fecal transplantation – which involves collecting and processing stool from a healthy donor, and delivering it into a recipient’s gut – might help to ameliorate disease in these people, according to Round.

Loss of MyD88 disturbs the microbial community because it disrupts production of IgA. This class of antibody works like a gatekeeper that controls which types of bacteria, and how many, are allowed to inhabit the gut. By performing inventories of total gut bacteria compared to species that bind IgA, the scientists determined that without MyD88, IgA failed to recognize species that it can otherwise.

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