“The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics”
This is very interesting study in support of my hypothesis that microbes are nothing but form of Prana with special purpose. Body cells without identity of known organ classification. They are bridge between us and environment. They are translator of environmental impact on body. They are reflection of bodily health state. In short, this form of prana is never an enemy! Just a faithful servant of mother nature, at our service until we ignore them and try to get rid of them by modern practices.
This study testifies importance of two things which Sanatana Dharma based living openly prescribes:
- Living in joint family is natural immunity booster
- Household plays critical role in shaping our prana hence our health. Vastu Vidya plays invisible role in maintaining your health.
- Home surrounded by mother nature helps a lot
- The most significant impact on salivary microbes is by the food we eat and medium used for cleaning the teeth and mouth. If you are using toothpaste and chemical cocktail to gargle, you are at significant loss of healthy prana i.e. good bacteria in oral cavity.
- Oral health had direct connection to heart. This way, your home environment, both physical, mental, play role in your health!
Old notes on Saliva
HOUSEHOLD ENVIRONMENT—NOT GENETICS—SHAPES SALIVARY MICROBES
“It’s generally becoming known that there’s a link between our microbiomes and our health and that’s reason enough to find out what’s in there, how they arrived there, and what they are doing,”
“The oral cavity is naturally colonized by hundreds of bacterial species, which stop external pathogens from establishing a foothold, but they also can themselves cause oral disease.”
Spouses and parents and children younger than 10 living in a household together had the most similar saliva microbiomes. “The contact doesn’t even have to be intimate, like kissing,” says Roberts. “Individuals’ hands are covered in saliva and they are touching everything in the house.” Children younger than 10 had more similar bacteria to their parents than older children, perhaps reflecting that older children are becoming “more independent individuals,” says Roberts.
The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics: Evidence from a Large Family of Closely Related Individuals
The human microbiome is affected by multiple factors, including the environment and host genetics. In this study, we analyzed the salivary microbiomes of an extended family of Ashkenazi Jewish individuals living in several cities and investigated associations with both shared household and host genetic similarities. We found that environmental effects dominated over genetic effects. While there was weak evidence of geographical structuring at the level of cities, we observed a large and significant effect of shared household on microbiome composition, supporting the role of the immediate shared environment in dictating the presence or absence of taxa. This effect was also seen when including adults who had grown up in the same household but moved out prior to the time of sampling, suggesting that the establishment of the salivary microbiome earlier in life may affect its long-term composition. We found weak associations between host genetic relatedness and microbiome dissimilarity when using family pedigrees as proxies for genetic similarity. However, this association disappeared when using more-accurate measures of kinship based on genome-wide genetic markers, indicating that the environment rather than host genetics is the dominant factor affecting the composition of the salivary microbiome in closely related individuals. Our results support the concept that there is a consistent core microbiome conserved across global scales but that small-scale effects due to a shared living environment significantly affect microbial community composition.