Microbes

Microbes

Microbes Control Food Habits

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Case Study 1
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During recent talk with my family, one shocking thing was discussed about fast food habit.

Some of my nephew’s friends are migrants. Well-to-do migrants from other states. Settling down in our city. So these families often eat outside. Almost everyday, something comes from outside. Junk or almost junk.

These kids don’t really like home cooked food now. Addicted to the taste of junk.

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Case Study 2
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One couple working in IT in pune I know.1 Gas cylinder works for almost 1 year for them. You can imagine their usage.

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Why are we so addicted to junk food?

Our gut microbes dictate what we eat. If you have a healthy gut, the microbes will direct you to foods that are required by your body for fitness. However if your gut microbes are disturbed they may start cravings for food that destroys your health. Parents of autistic children noticed food cravings in their children which aggravated their conditions. They then devised diets that controlled this and led to improved behavior. Many of them blamed the vaccines and the consequent use of antibiotics for vaccine after effects for this. They have been traditionally ridiculed for their ‘strange theories’ that don’t fit the industrial model of medicine. However researchers are now confirming what these ‘unscientific’ parents discovered.

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Now my dear doctor friends debate with me that it is safer to give antibiotics to avoid risks. What risks? Why are we so fearful and fear mongering? Why can’t doctor sense right condition and avoid unnecessary antibiotics and by that protect GUT microbes?

Or at least, think and prefer pause on your eating cravings. Even toxins rich food cooked at home is worth compare to junk/restaurant food.

Reason? When cooked at home, it is full of microbes suited to you and family. So relatively safe. Outside food?

All random, chaotic microbes with your food. You never know when they will alter your eating habits and control you like slave. 🙂

Read this if you are interested more.


Research


Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms

MicrobesFoodHabit

Like microscopic puppetmasters, microbes may control the eating behavior of hosts through a number of potential mechanisms including microbial manipulation of reward pathways, production of toxins that alter mood (shown in pink, diffusing from a microbe), changes to receptors including taste receptors, and hijacking of neurotransmission via the vagus nerve (gray), which is the main neural axis between the gut and the brain.

 

Abstract

Microbes in the gastrointestinal tract are under selective pressure to manipulate host eating behavior to increase their fitness, sometimes at the expense of host fitness. Microbes may do this through two potential strategies: (i) generating cravings for foods that they specialize on or foods that suppress their competitors, or (ii) inducing dysphoria until we eat foods that enhance their fitness. We review several potential mechanisms for microbial control over eating behavior including microbial influence on reward and satiety pathways, production of toxins that alter mood, changes to receptors including taste receptors, and hijacking of the vagus nerve, the neural axis between the gut and the brain. We also review the evidence for alternative explanations for cravings and unhealthy eating behavior. Because microbiota are easily manipulatable by prebiotics, probiotics, antibiotics, fecal transplants, and dietary changes, altering our microbiota offers a tractable approach to otherwise intractable problems of obesity and unhealthy eating.

http://onlinelibrary.wiley.com/doi/10.1002/bies.201400071/full

Bacteria and their hidden location

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The female internal reproductive organs are the vagina, uterus, uterine tubes (Fallopian tubes, oviducts) and ovaries.
The female internal reproductive organs are the vagina, uterus, uterine tubes (Fallopian tubes, oviducts) and ovaries.
lol..whenever modern medicine talks about sterile organ, I feel like laughing.
 
There is nothing like sterile in nature. Mother nature does not like vacuum. Whatever we term as sterile, is our limitation.
 
Bacteria are not the cause of the infection but depleted/vitiated Prana is.
 
” They’re inside our gut, on the skin, and in the mouth. Thousands of different types of micro-organisms live in and on the body, playing helpful roles in digestion or in aiding the body’s natural defense system. Now, scientists have found tiny organisms living in the upper female reproductive tract, an environment they said was once thought to be sterile. In a preliminary finding researchers revealed they have found bacteria in the ovaries and in the fallopian tubes. ” [1]
 
Be fearless. Learn to maintain the प्राणमय कोष by not indulging in sensorial gratification habits and Pranayam/ Sandhya. Good enough to protect against infections.
 
Oh yes, when there is prana depleted in environment (due to toxic gas propogation like Bhopal tragedy, not everything is in your hand as being inefficient in handling own prana ) So? Take care of Environment too!! Keep it healthy!! Do perform Agnihotra/Homa regularly.
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Research
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Bacteria found in female upper reproductive tract, once thought sterile

They’re inside our gut, on the skin, and in the mouth. Thousands of different types of micro-organisms live in and on the body, playing helpful roles in digestion or in aiding the body’s natural defense system. Now, scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have found tiny organisms living in the upper female reproductive tract, an environment they said was once thought to be sterile.

In a preliminary finding (abstract 5568) presented Monday, June 6, at the 2016 American Society of Clinical Oncology Annual Meeting in Chicago, researchers revealed they have found bacteria in the ovaries and in the fallopian tubes. And with an additional finding that women with ovarian cancer have a different bacterial makeup, researchers are asking whether these tiny organisms could play a role in cancer development or progression.

“This is a place essential to the beginning of life – you don’t expect that it’s a place that’s teeming with bacteria,” said Wendy R. Brewster, MD, PhD, a UNC Lineberger member, an associate professor in the UNC School of Medicine Department of Obstetrics & Gynecology, and director of the UNC Center for Women’s Health Research. “But there are bacteria in chemical pits at the bottom of the ocean, so why not in the fallopian tubes? Our proof of principle study has determined that while the upper female reproductive tract certainly isn’t teeming with bacteria, there are bacteria present.”

 
[1] http://www.eurekalert.org/pub_releases/2016-06/uonc-bfi060316.php

A Link Between Gut Bacteria and Neurogenesis: Mouse Study

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I shared here many times that प्राण is cellular intelligence and memory. Mar the प्राण, do not retain प्राण and your body cells lose intelligence.

Lost cellular intelligence = Zombie cells = Prone to proliferation, inflammation, retard responses.

Here is the paper in support of this observation.

antibiotics = lack of prana = brain development hampered = memory function impaired.


Research


A Link Between Gut Bacteria and Neurogenesis: Mouse Study

Summary: According to a new mouse study, antibotics that are strong enough to kill gut bacteria can also halt the growth of hippocampal neurons.

Source: Cell Press.

http://neurosciencenews.com/neurogenesis-gut-bacteria-4253/

http://www.cell.com/cell-reports/pdf/S2211-1247(16)30518-6.pdf

Antibiotics strong enough to kill off gut bacteria can also stop the growth of new brain cells in the hippocampus, a section of the brain associated with memory, reports a study in mice published May 19 in Cell Reports. Researchers also uncovered a clue to why– a type of white blood cell seems to act as a communicator between the brain, the immune system, and the gut.

“We found prolonged antibiotic treatment might impact brain function,” says senior author Susanne Asu Wolf of the Max-Delbrueck-Center for Molecular Medicine in Berlin, Germany. “But probiotics and exercise can balance brain plasticity and should be considered as a real treatment option.”

Wolf first saw clues that the immune system could influence the health and growth of brain cells through research into T cells nearly 10 years ago. But there were few studies that found a link from the brain to the immune system and back to the gut.

In the new study, the researchers gave a group of mice enough antibiotics for them to become nearly free of intestinal microbes. Compared to untreated mice, the mice who lost their healthy gut bacteria performed worse in memory tests and showed a loss of neurogenesis (new brain cells) in a section of their hippocampus that typically produces new brain cells throughout an individual’s lifetime. At the same time that the mice experienced memory and neurogenesis loss, the research team detected a lower level of white blood cells (specifically monocytes) marked with Ly6Chi in the brain, blood, and bone marrow. So researchers tested whether it was indeed the Ly6Chi monocytes behind the changes in neurogenesis and memory.

In another experiment, the research team compared untreated mice to mice that had healthy gut bacteria levels but low levels of Ly6Chi either due to genetics or due to treatment with antibodies that target Ly6Chi cells. In both cases, mice with low Ly6Chi levels showed the same memory and neurogenesis deficits as mice in the other experiment who had lost gut bacteria. Furthermore, if the researchers replaced the Ly6Chi levels in mice treated with antibiotics, then memory and neurogenesis improved.

“For us it was impressive to find these Ly6Chi cells that travel from the periphery to the brain, and if there’s something wrong in the microbiome, Ly6Chi acts as a communicating cell,” says Wolf.

Researchers connect brain blood vessel lesions to intestinal bacteria

https://www.ninds.nih.gov/News-Events/News-and-Press-Releases/Press-Releases/Researchers-connect-brain-blood-vessel-lesions

A study in mice and humans suggests that bacteria in the gut can influence the structure of the brain’s blood vessels, and may be responsible for producing malformations that can lead to stroke or epilepsy. The research, published in Nature, adds to an emerging picture that connects intestinal microbes and disorders of the nervous system. The study was funded by the National Institute of Neurological Disorders and Stroke (NINDS), a part of the National Institutes of Health (NIH).

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled blood vessels that can lead to seizures or stroke when blood leaks into the surrounding brain tissue. A team of scientists at the University of Pennsylvania investigated the mechanisms that cause CCM lesions to form in genetically engineered mice and discovered an unexpected link to bacteria in the gut. When bacteria were eliminated the number of lesions was greatly diminished.

“This study is exciting because it shows that changes within the body can affect the progression of a disorder caused by a genetic mutation,” said Jim I. Koenig, Ph.D., program director at NINDS.

Gut is not Gutter : Your gut bacteria don’t like junk food – even if you do

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Do you like to visit dirty and untidy homes? Do you give the same treatment to your relatives and friends when they visit your home? Do we scold them for coming at wrong time?

GUT is home for billions of bacteria. They stay their to do numerous biological tasks for our well-being. In fact, their population variety decides, what nutrients we can digest and what not. Their population really drives our emotional responses. Richness in their variety is essential.

We rely on our bacteria to produce much of our essential nutrients and vitamins while they rely on us eating plants and fruits to provide them with energy and to produce healthy chemicals which keep our immune system working normally.

We are unlikely to stop people eating fast food, but the devastating effects on our microbes and our long term health could possibly be mitigated if we also eat foods which our microbes love like probiotics (yogurts), root vegetables, nuts, olives and high-fibre foods. What they seem to crave, above all else, is food diversity and a slice of gherkin in the burger just isn’t enough.

When we keep eating junk food, we kill them. We show them the door.

Tim Spector, Professor of Genetic Epidemiology at King’s College London, did an experiment with his own son.

Read to know how junk food destroys GUT population.


Research


Your gut bacteria don’t like junk food – even if you do

https://theconversation.com/your-gut-bacteria-dont-like-junk-food-even-if-you-do-41564

“Tom’s gut had seen massive shifts in his common microbe groups for reasons that are still unclear. Firmicutes were replaced with Bacteroidetes as the dominant type, while friendly bifidobacteria that suppress inflammation halved. However the clearest marker of an unhealthy gut is losing species diversity and after just a few days Tom had lost an estimated 1,400 species – nearly 40% of his total. The changes persisted and even two weeks after the diet his microbes had not recovered. Loss of diversity is a universal signal of ill health in the guts of obese and diabetic people and triggers a range of immunity problems in lab mice.”

Bacteria to Treat Diabetes : प्राणमयकोष से प्रमेह तक

PranaDiabetes

Microbes

Few days back, I shared post about kids eating exclusive items like soil , chalk etc. It was about Pranic intellligence directing innocent kids.

Some infants intuitively eat soil. Some eat lime chalk. They do it due to lack of wholesomeness. They lack something. Some material nutrients and some emotional. Who drives their under-development senses and intellect and take such intelligent decisions?

प्राणमय शरीर.

As we grow, we lose our प्राण. But we hardly get engaged in प्राण refilling. प्राणायाम was not some exclusive fancy exercise that some Baba advertise and we perform in garden or 5 Star resort (call it Ashram 😉). Sometimes, we lose more than our refilling capacity so impact is never observed. Since refilling is not happening, we slowly lose our intuitive intelligence. So our Gut feeling or hunch hardly works 🙂 It gives wrong directions. Wrong decisions. Vicious cycle. Day comes when even we cannot perform simple wound healing. Doctors call it Diabetes.

Got it? It is प्राणमय शरीर that takes care अन्नमय कोश. Pay attention to it!

Refilling should be performed for each शुभ action,daily. For all time and mission critical activities, we seek help from friends and relatives and perform Yajna together so overall local environment’s प्राण refilling happen. For example, वास्तु पूजन or सत्यनारायण कथा etc.”

Today I read this. Here is the novel way to treat diabetes i.e. Use healthy bacteria.
 
Bacteria = Physical manifestation of प्राणमयकोश. Cells who could not unite for specific purpose but still are in service of our existence. They remain as bacteria, 10 times more in number compare to body cells.
 
In short, take care of प्राणमयकोश and things will again get in place for long healthy life. 🙂
 
Unnecessarily focused on sugar,insulin and some costly medicinal stuff :). (Well, white sugar is still a poison. So when you eat lot of it, प्राणमयकोश is at work with intense pressure and so it diminishes faster due to overuse of Apana Vayu (Type of Prana)… and its replacement Sugarfree? ..double poison!! ) But good sugar should not be left for some irrational science. 😉 (Y)
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Research
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Treating diabetes with beneficial bacteria

Treating diabetes with beneficial bacteria

University of Minnesota researchers are on a mission to treat diabetes, and they’ve enlisted a few trillion microscopic helpers.

In place of drugs or surgery, a team of researchers is studying how to improve diabetes patients’ insulin sensitivity by introducing trillions of beneficial bacteria into their intestines. Researchers believe this unusual approach, conducted through a fecal microbiota transplant, could improve how the body regulates blood sugar, the central problem in diabetics. The project is part of MnDRIVE (Minnesota’s Discovery, Research and InnoVation Economy), a $36 million biennial investment by the state that aims to solve grand challenges. As a part of MnDRIVE’s Transdisciplinary Research Program, the project will bridge multiple fields of research and bring together experts from across the U to work on the same clinical trial.

Patients with diabetes have too much glucose in their blood, which leads to a host of serious health problems, from heart disease to obesity. Dr. Alexander Khoruts, a gastroenterologist at the U of M and lead principal investigator on the project, said the right balance of bacteria has the potential to improve the body’s energy metabolism, in part by enhancing insulin function. Insulin drives glucose from blood into cells of the body.

“If we can improve insulin sensitivity, we will correct the central metabolic problem responsible for diabetes,” Khoruts said. “Diabetes is one of the main complications of metabolic syndrome, which is also associated with obesity, high blood pressure and liver disease. If we improve insulin sensitivity, we hope some of the other problems may also get better.”

To understand the composition of microbes present before and after the transplant, Khoruts is working with Michael Sadowsky, Ph.D., director of the U’s BioTechnology Institute. As a microbial ecologist, Sadowsky studies the complex science of how microbes interact in their environment. People who are diabetic or obese tend to have a less diverse microbiome – or microbial community – in their gut. In turn, they are less able to produce important short-chain fatty acids, which may regulate many functions in the body, including appetite, glucose production, metabolic rate and the immune system. Khoruts and Sadowsky believe that a more diverse microbial gut community should be able to produce more short-chain fatty acids that will have a number of beneficial effects for the patients.

Wound Healing : Thanks to wonder that is skin microbes!

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Few days back, I shared that I had a deep cut on hand and I applied Gau mutra on it. I followed it for a week. Along with Gau mutra, I also used to massage the wound with my early morning saliva. Wound is not only healed, skin color is also emerged back to normal color.

Who helped me?

Short answer: Skin microbes.

Long understanding: Gau mutra and Saliva controlled my skin friend microbes i.e. my प्राणमय कोष so that विकृत प्राण or प्राण against my prakruti does not assimilate at wound location.

Here is the paper supporting this theory:

Chronic wounds—cuts or lesions that just never seem to heal—are a significant health problem, particularly among elderly people. An estimated 1 in 20 elderly people live with a chronic wound, which often results from diabetes, poor blood circulation or being confined to bed or a wheelchair.
“These wounds can literally persist for years, and we simply have no good treatments to help a chronic wound heal,”

The trillions of bacteria that live on and in our bodies have attracted a great deal of scientific interest in recent years. Findings from studies of microbes in the gut have made it clear that although some bacteria cause disease, many other bacteria are highly beneficial for our health.

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Gobar, mutra, saliva (GMS) are natural bio-healers. While modern medicine has no solution for chronic wounds in elder people with already depleted प्राणमय कोष, GMS can help greatly.


Research


Bacteria on the Skin: New Insights on Our Invisible Companions

Study examines how skin-dwelling bacteria influence wound healing; findings could help address chronic wounds, a common ailment in the elderly

http://www.newswise.com/articles/bacteria-on-the-skin-new-insights-on-our-invisible-companions

Chronic wounds—cuts or lesions that just never seem to heal—are a significant health problem, particularly among elderly people. An estimated 1 in 20 elderly people live with a chronic wound, which often results from diabetes, poor blood circulation or being confined to bed or a wheelchair.

“These wounds can literally persist for years, and we simply have no good treatments to help a chronic wound heal,” said Hardman, who added that doctors currently have no reliable way to tell whether a wound will heal or persist. “There’s a definite need for better ways to both predict how a wound is going to heal and develop new treatments to promote healing.”

In their recent study, Hardman and his colleagues compared the skin bacteria from people with chronic wounds that did or did not heal. The results showed markedly different bacterial communities, suggesting there may be a bacterial “signature” of a wound that refuses to heal.

“Our data clearly support the idea that one could swab a wound, profile the bacteria that are there and then be able to tell whether the wound is likely to heal quickly or persist, which could impact treatment decisions,” said Hardman.

Biogeography ,Human Skin Microbes and प्राणमय कोष

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SKinMicrobes
Germ-phobia has penetrated our collective psyche so deeply that we see persons not using regular hand-wash/DEttol with special jaundiced vision.
 
Compulsion of using Dettol is yet another pseudo-scientific phobia.
 
In reality, our skin bacteria remains pretty stable. Despite regular washing and contact with bacteria-laden objects, our personal milieu of skin microbes remains highly stable over time, reports a metagenomics study.
 
What exactly we clean is: remaining odor and substance if any (Post meal, post visiting toilet or post-outside activity like sports). Only water is enough. If the substance is oily, use dung ash i.e. activated charcoal. There is nothing like germ-cleaning. So Dettol and all : waste of money and compromise with immunity. 🙂
 
Our skin microbes are manifested based on our energy footprints. Our प्राणीक footprint. And they remain pretty much stable. They become unstable if your skin has tendency to remain dry. If such is the case (dry skin), coconut or ghee massage is must.
 
Dry skin = unstable Prana = unstable and more variety of microbes.
 
•Composition of skin microbiome (bacteria, fungi, and viruses) is shaped by physiology
 
•Conservation of skin microbial communities can vary by site and individual
 
•Skin microbial communities are stable at the strain level, despite external exposures
 
•Eukaryotic viruses are the most transient members of the skin community

Despite regular washing and contact with bacteria-laden objects, our personal milieu of skin microbes remains highly stable over time, reports a metagenomics study published May 5 in Cell. The authors say this knowledge could be applied to better understand a wide range of human skin disorders through the development of prebiotic, probiotic, and microbial transplantation approaches.

Human skin is an ecosystem composed of a wide range of habitats for bacteria, fungi, and viruses. While most of these microbes are harmless or beneficial, some have been linked to skin disorders such as acne, psoriasis, and eczema. Studying the variability of microbial communities across skin sites has been key to understanding, for instance, why eczema tends to affect moist sites such as the bends of the arms and legs, while psoriasis commonly occurs on dry, exposed sites such as the elbows and knees. However, it has not been clear how microbial communities found across skin sites change over time and how these changes may affect human health.

What is written in red in above research quote is actually true. With aging, our प्राण combination changes. To direct life-friendly change with age, हनुमान & गणेश पूजा is must for गृहस्थ.

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Research
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Temporal Stability of the Human Skin Microbiome

Biogeography and individuality shape the structural and functional composition of the human skin microbiome. To explore these factors’ contribution to skin microbial community stability, we generated metagenomic sequence data from longitudinal samples collected over months and years. Analyzing these samples using a multi-kingdom, reference-based approach, we found that despite the skin’s exposure to the external environment, its bacterial, fungal, and viral communities were largely stable over time. Site, individuality, and phylogeny were all determinants of stability. Foot sites exhibited the most variability; individuals differed in stability; and transience was a particular characteristic of eukaryotic viruses, which showed little site-specificity in colonization. Strain and single-nucleotide variant-level analysis showed that individuals maintain, rather than reacquire, prevalent microbes from the environment. Longitudinal stability of skin microbial communities generates hypotheses about colonization resistance and empowers clinical studies exploring alterations observed in disease states.

 

 

Prana heals : UCLA research suggests that Gut Microbes Prevents Cancer

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But we eat mindless acidic food so that bacteria can hardly reach GUT via digestive track.
We kill mouth bacteria by using toothpaste.
We kill them by handwash and soaps.
We hardly spend physically active time under the sun.
Our food lack supporting nutrition so that bacteria can travel and stabilize at Gut.
Mindless usage of antibiotics.
 
And then we are shocked by sudden increase in cancer cases! 😉
 
As a society, unless we correct our priorities, we will celebrate Cancer hospitals as human success milestones. 😛 😀
Microbes = Prana
Prana is an ultimate healer.
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Research
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UCLA research suggests that gut bacteria could help prevent cancer

https://www.uclahealth.org/news/ucla-research-suggests-that-gut-bacteria-could-help-prevent-cancer

“It is not invasive and rather easy to do,” he said.

Over millions of years, gut bacteria have evolved into both good and bad types: The good ones have anti-inflammatory properties and the bad ones promote inflammation. The human body typically contains about 10 trillion bacterial cells, compared with only 1 trillion human cells.

Schiestl and his colleagues isolated a bacterium called Lactobacillus johnsonii 456, which is the most abundant of the beneficial bacteria, and which has some pretty useful applications outside of medicine. “Since it is a Lactobacillus strain, it makes excellent yogurt, kefir, kombucha and sauerkraut.”

In the UCLA study the bacterium reduced gene damage and significantly reduced inflammation — a critical goal because inflammation plays a key role in many diseases, including cancer, neurodegenerative diseases, heart disease, arthritis and lupus, and in the aging process.

Previous research led by Schiestl presented the first evidence of a relationship between intestinal microbiota and the onset of lymphoma, a cancer that originates in the immune system. The new study explains how this microbiota might delay the onset of cancer, and suggests that probiotic supplements could help keep cancer from forming.

For both studies, Schiestl and his team used mice that had mutations in a gene called ATM, which made them susceptible to a neurologic disorder called ataxia telangiectasia. The disorder, which affects 1 in 100,000 people, is associated with a high incidence of leukemia, lymphomas and other cancers.

The mice were divided into two groups — one that was given only anti-inflammatory bacteria and the other that received a mix of inflammatory and anti-inflammatory microbes that typically co-exist in the intestines.

In the Cancer Research paper, Schiestl and his team showed that in the mice with more of the beneficial bacteria, the lymphoma took significantly longer to form.

In the new study, the researchers analyzed the metabolites — molecules produced by the gut’s natural metabolic action — in the mice’s urine and feces. The scientists were surprised to find that the mice that were receiving only the beneficial microbiota produced metabolites that are known to prevent cancer. Those mice also had more efficient fat and oxidative metabolism, which the researchers believe might also lower the risk for cancer.

Among the other results, in the mice receiving only the good bacteria, lymphoma formed only half as quickly as it did in the other mice. In addition, mice with the good bacteria lived four times longer and had less DNA damage and inflammation.

Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis

Abstract

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151190

Intestinal microbiota play a significant role in nutrient metabolism, modulation of the immune system, obesity, and possibly in carcinogenesis, although the underlying mechanisms resulting in disease or impacts on longevity caused by different intestinal microbiota are mostly unknown. Herein we use isogenic Atm-deficient and wild type mice as models to interrogate changes in the metabolic profiles of urine and feces of these mice, which are differing in their intestinal microbiota. Using high resolution mass spectrometry approach we show that the composition of intestinal microbiota modulates specific metabolic perturbations resulting in a possible alleviation of a glycolytic phenotype. Metabolites including 3-methylbutyrolactone, kyneurenic acid and 3-methyladenine known to be onco-protective are elevated in Atm-deficient and wild type mice with restricted intestinal microbiota. Thus our approach has broad applicability to study the direct influence of gut microbiome on host metabolism and resultant phenotype. These results for the first time suggest a possible correlation of metabolic alterations and carcinogenesis, modulated by intestinal microbiota in A-T mice.

मातृप्राण (Maternal Microbes) drives immunity development

In my native culture, pregnant mothers are asked to eat ghee based food during last trimester. Along with it, curd rice.

PregnancyFood

I am sure similar regimes must exist in all cultures who prefer intellectually and physically strong generations. Ask your grandmother, she can guide. Her is the last generation with traditional legacies.

Ghee and Curd when produced from Zebu cattle (Indian breed), it is rich in GUT-friendly microbes. Healthy food for mother ==> Good immunity of child. This is because Zebu cattle’s physiology allows her to transform maximum प्राण from the Sun.

Basically, everything sums up as Prana.

प्राणवान mother = Child with great immunity. प्राण is cellular intelligence that helps to identify and act upon non-self matters and purge them.

Ghee and Curd are full of प्राण.

“During gestation, a mother’s microbiome shapes the immune system of her offspring, a new study in mice suggests. While it’s known that a newborn’s gut microbiota can affect its own immune system, the impact of a mother’s microbiota on her offspring has largely been unexplored.”


Research


https://www.eurekalert.org/pub_releases/2016-03/aaft-mmi031416.php

Mom’s microbes influence her offspring’s immune system, mice study shows

 Credit Mercedes Gomez de Agüero, Stephanie Ganal-Vonarburg, Kathy D. McCoy, and Andrew J. Macpherson

Credit
Mercedes Gomez de Agüero, Stephanie Ganal-Vonarburg, Kathy D. McCoy, and Andrew J. Macpherson

During gestation, a mother’s microbiome shapes the immune system of her offspring, a new study in mice suggests. While it’s known that a newborn’s gut microbiota can affect its own immune system, the impact of a mother’s microbiota on her offspring has largely been unexplored. Here, Mercedes Gomez de Agüero et al. infected the guts of pregnant mice with E.coli engineered to dwindle over time, allowing the mothers to become germ-free again around the time they gave birth. This temporary colonization of E.coli in the mother affected the immune system of her offspring; after birth, the offspring harbored more innate lymphoid and mononuclear cells in their intestines compared to mice born to microbe-free pregnant mothers. Similar results were seen when pregnant mothers were temporarily colonized with a cocktail of eight other microbes. An RNA analysis of offspring born to gestation-only colonized mothers compared with controls revealed greater expression of numerous genes, including those that influence cell division and differentiation, mucus and ion channels, and metabolism and immune function. By transferring serum from bacteria-colonized pregnant mice to non-colonized pregnant mice, the researchers found that maternal antibodies likely facilitate the transmission and retention of microbial molecules from a mother to her offspring. The results of this study add another surprising chapter to the growing body of literature surrounding the effects of the gut microbiota on immune functioning.

Gau Prasad (गौ प्रसाद – पंचगव्य – Microbes) can cure radiation-induced toxicity

Radiation

Problem with cow promoters in India is that they don’t talk the language of mass. And sometimes, become object of mockery.

One such case was when it was proclaimed that cow dung can protect against the radiation.

Yes, it does. How? Most of the times, we don’t have citations to support it.

Here is one research to help connect the dots.

Faecal microbiota transplantation (FMT) increased the survival rate of irradiated animals, elevated peripheral white blood cell counts and improved gastrointestinal tract function and intestinal epithelial integrity in irradiated male and female mice.


Remember one thing : Microbes are manifestation of Prana. Like how your body cells are. Life is interplay of different forms of Prana. Microbes, no exception.

If the faecal transplant can help protecting against radiation-induced toxicity, panchgavya (product made up of 5 prasad, rich in the form of microbes) can do wonder.

Faecal of an individual is not perfect but cow dung and urine of desi cow is perfect when cow is taken care well. (Well-fed, stress-free, grazing)


Research


Faecal microbiota transplantation protects against radiation‐induced toxicity

Severe radiation exposure may cause acute radiation syndrome, a possibly fatal condition requiring effective therapy. Gut microbiota can be manipulated to fight against many diseases. We explored whether intestinal microbe transplantation could alleviate radiation‐induced toxicity. High‐throughput sequencing showed that gastrointestinal bacterial community composition differed between male and female mice and was associated with susceptibility to radiation toxicity. Faecal microbiota transplantation (FMT) increased the survival rate of irradiated animals, elevated peripheral white blood cell counts and improved gastrointestinal tract function and intestinal epithelial integrity in irradiated male and female mice. FMT preserved the intestinal bacterial composition and retained mRNA and long non‐coding RNA expression profiles of host small intestines in a sex‐specific fashion. Despite promoting angiogenesis, sex‐matched FMT did not accelerate the proliferation of cancer cells in vivo. FMT might serve as a therapeutic to mitigate radiation‐induced toxicity and improve the prognosis of tumour patients after radiotherapy.

Faecal microbiota transplantation ameliorates radiation‐induced toxicity in irradiated mice by improving gastrointestinal tract function and epithelial integrity, preserving gut bacterial composition and maintaining the small intestine transcriptome.

  • Gut microbiota determines the radiosensitivity of hosts.

  • Faecal microbiota transplantation (FMT) fights against radiation‐induced gastrointestinal toxicity.

  • FMT preserves enteric bacterial composition and retains the RNA expression profile of irradiated hosts.

  • FMT might emerge as a therapeutic schedule in tumour radiotherapy to improve prognosis.

Read more: http://embomolmed.embopress.org/content/early/2017/02/27/emmm.201606932

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Toilet Obsession: Epic Water Waste

Ambitious political schemes and govt campaigns often don't consider crucial facts associated with mass level implementation. When Central govt announced toilet schemes, I asked my...