Microbes

Microbes

Seat of the Prana: Heart Attack and Gut Microbes: Part 1

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F4.large

A recent study point out that Microbial communities play significant role in make or break of heart by causing or avoiding heart attack.

Read the research abstract summary first[1]

The gut is a major reservoir of T cells and diverse resident microbes, microbiota, which can influence immune responses in sites distant from the mucosal surfaces. Complete sterilization of the gut has proven to be beneficial in some experimental models of T cell mediated diseases, whereas partial recolonization post sterilization leads to microbial perturbations, a process called dysbiosis, and, worsens the outcome. Gut dysbiosis is thus recently becoming associated with the pathogenesis of several diseases, in part, by mechanisms in which certain bacteria promote T cell activation and enhance disease progression in a vicious cycle. The complex syndrome of heart failure (HF), a leading cause of morbidity and mortality affecting more than 24 million people worldwide, is recently becoming associated with gut dysbiosis and T cell mediated systemic inflammation in patients, but the mechanisms regulating this emerging gut-heart axis, and whether T cell activation and heart infiltration play a role remains unclear. We have previously reported that T cells infiltrate the heart in patients with non-ischemic HF, and using the transverse aortic constriction (TAC) mouse model of HF, demonstrated that T cells are critical regulators of adverse cardiac remodeling and HF. We hypothesized that sterilization of the gut by microbiota depletion prevents adverse cardiac remodeling and HF in a T cell dependent manner. C57/BL6 mice were orally treated with a well-established cocktail of antibiotics and antifungal (ABX) and subjected to TAC or Sham surgery. ABX treatment started 1 week before TAC surgery and was terminated 4 weeks after TAC. In vivo transthoracic echocardiography and hemodynamics showed a preserved ejection fraction and fractional shortening in mice treated with ABX as compared to untreated mice. Furthermore, gut microbiota depletion with ABX resulted in decreased left ventricular interstitial and perivascular fibrosis, and decreased cardiac hypertrophy in response to TAC, as compared to non-ABX treated TAC mice. These changes correlated with significant reduction of CD4 T cell activation in the mediastinal lymph nodes (mLNs) draining the heart, determined by FACS, as well as in the number of CD4 T cells infiltrated in the heart in ABX treated mice. Our findings indicate that ABX treatment results in distal effects in T cell activation occurring during TAC and protects from adverse cardiac remodeling, supporting the potential importance of gut microbiota in pressure overload induced HF. Future studies will determine whether dysbiosis post ABX treatment contributes to pathological cardiac remodeling and the mechanisms regulating the gut-heart axis in non-ischemic HF.

Let us first understand few terms and entities.

What is Gut dysbiosis?

Gut dysbiosis, sometimes called bacterial dysbiosis, means you have a lack of beneficial bacteria in your gastrointestinal (GI) tract.

There are approximately over 400 species of bacteria in your system that make up your gut microbiome. You actually have more bacteria in your gut than you do cells in your body! These bacteria help you digest food, synthesize vitamins, and fight off harmful pathogens. In short, gut bacteria are a fundamental part of your health, and without them you wouldn’t be able to survive.

[2]

What are T-cells (T-Lymphocytes (T-Cells))?

A type of white blood cell. T-lymphocytes are part of the immune system and develop from stem cells in the bone marrow. They help protect the body from infection and may help fight cancer. Also called T cell and thymocyte.

When our body lacks life-enriching Prana, naturally, it is being captured by life-consuming prana. Life-consuming prana or Prana doing job of destruction, flows from GUt to heart and disturbs its working.

Inflammed GUT due to idiotic eating habits, will generate flood of T-cells. When these T-cells travel to Heart, they are responsible for heart failure as per research.


My understanding


Body is made up of srota or channels. Channel that transports Prana, is known as Pranavaha Srotas. It’s root is in heart (left chamber). Seat is in heart. It receives Prana from two places. Lungs and gastrointestinal tract. It is also connected to GUT/Colon. Clogged colon or inflamed GUT , not only disturbs Prana transport but also affect breathing, and vice a versa. If breathing is not proper, GUT/Colon will be disturbed.
 
Heart attack is easy to detect very early by person’s eating habits. Irregular meals, obsession for exotic food against age, gender, season and time of the day, obsession for specific rasa (sweet teeth) – all of them play role in destroying GUT and in turn disturbing Prana transportation by polluting heart the root of the Pranavaha channel.

More in next part…

[1] https://www.fasebj.org/doi/10.1096/fasebj.2018.32.1_supplement.287.3

[2] https://blog.kettleandfire.com/gut-dysbiosis/

 

Milk is not product or supplement, but प्रसाद(prasad) & प्रेम(love)!

MilkMicrobes

Since we are now brainwashed to see packaging and standard factory finishing as quality measure, we also see naturally available food with same lens. I often receive complaint from my family and friends that Gau shala milk is not of same quality every day! It is not possible! You are underrating grand design principles of महाप्राण!

During pregnancy, grand-mother always prescribes some work until 7th month.

But our modern moms don’t like this advice. They love chatting on whatsapp. They love watching TV.

Results into?

More Weight gain than expected.

The heavier the mother, the fewer the bacteria in the breastfeeding.

The study also reveals that the milk of overweight mothers or those who put on more weight than recommended during pregnancy contains a lesser diversity of species.

Spanish researchers have traced the bacterial microbiota map in breast milk, which is often the main source of nourishment for newborns. The study has revealed a larger microbial diversity than originally thought: more than 700 species.

Breast milk is recognized as the most important postpartum element in metabolic and immunologic programming of health of neonates. The factors influencing the milk microbiome and the potential impact of microbes on infant health have not yet been uncovered.

Imagine the vaccum of good bacteria when the breast-fed is replaced by formula feeding?

Similar pro-life prana (bacteria) is present in Gau mata’s milk. But we pasteurize it! 🙁

Reason why lean and freely grazing cows give more nutritious milk than cows kept in curfew?

Games of MahaPrana!

Ghor KaliyugA! 🙁


Research


The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery

Background: Breast milk is recognized as the most important postpartum element in metabolic and immunologic programming of health of neonates. The factors influencing the milk microbiome and the potential impact of microbes on infant health have not yet been uncovered.

Objective: Our objective was to identify pre- and postnatal factors that can potentially influence the bacterial communities inhabiting human milk.

Design: We characterized the milk microbial community at 3 different time points by pyrosequencing and quantitative polymerase chain reaction in mothers (n = 18) who varied in BMI, weight gain, and mode of delivery.

Results: We found that the human milk microbiome changes over lactation. Weisella, LeuconostocStaphylococcusStreptococcus, and Lactococcus were predominant in colostrum samples, whereas in 1- and 6-mo milk samples the typical inhabitants of the oral cavity (eg, VeillonellaLeptotrichia, and Prevotella) increased significantly. Milk from obese mothers tended to contain a different and less diverse bacterial community compared with milk from normal-weight mothers. Milk samples from elective but not from nonelective mothers who underwent cesarean delivery contained a different bacterial community than did milk samples from individuals giving birth by vaginal delivery, suggesting that it is not the operation per se but rather the absence of physiological stress or hormonal signals that could influence the microbial transmission process to milk.

Conclusions: Our results indicate that milk bacteria are not contaminants and suggest that the milk microbiome is influenced by several factors that significantly skew its composition. Because bacteria present in breast milk are among the very first microbes entering the human body, our data emphasize the necessity to understand the biological role that the milk microbiome could potentially play for human health.

https://academic.oup.com/ajcn/article/96/3/544/4576808

 

महाप्राण (MahaPrana), Bacteria and Oxygen Generation by plants

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Cynobacteria

Sometime back I shared how Mitochondria – the power house of the cell resembles to bacterial functions. And scientists even debate to call them bacteria! (https://www.youtube.com/watch?v=durqRtrN700)

Now, another link speaks the same about cyanobacteria and photosynthesis !

One more study that helps us realize value of महाप्राण!!

Ultimately, it is महाप्राण and its different forms that drives the living organisms!

Old note:

One friend asked me:

“Why do you call bacteria as just another form of Prana that is not manifested as any multi-cellular organism like human body? And they are no enemies!”

Me: “Because, at the end, we all are manifestation of Prana. Like our body cells, bacteria too are manifestation of Prana.”

Friend: “I am not convinced.”

Me: “Do you know Mitochondria?”

Friend: “No”

Me: “Mitochondria is an organelle found in large numbers in most cells, in which the biochemical processes of respiration and energy production occur. So basically it helps cell in energy production. And for your surprise, they are structurally same as bacteria! A Bacteria within cell! Just like how Prana’s manifestation within cell i.e. Mitochondria is helping cells, they also help outside cell, as a bacteria. Basically, they, like other cells, perform their duties. All living organisms are alive to perform their duties!”

What we really need to realize is that immunity is not war but process of self-realization. Stronger the self-realization, better you can cope up with non-compatible prana manifestation in form of viruses, bacteria, toxins. Think about it 🙂

Listen this for more understanding! 🙂 (y)


Research


How do Plants Make Oxygen? Ask Cyanobacteria

“The ability to generate oxygen through photosynthesis—that helpful service performed by plants and algae, making life possible for humans and animals on Earth—evolved just once, roughly 2.3 billion years ago, in certain types of cyanobacteria. This planet-changing biological invention has never been duplicated, as far as anyone can tell. Instead, according to endosymbiotic theory, all the “green” oxygen-producing organisms (plants and algae) simply subsumed cyanobacteria as organelles in their cells at some point during their evolution.”

http://science.sciencemag.org/content/355/6332/1436

Gut Bacteria (Pranic Footprint-प्राणमय कोष) controls speed of tumor growth

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I have shared it many times that the ultimate way of cancer prevention is to restore Prana in body. It is lack of prana/blockage of Nadi, that causes cancer.

Gut Bacteria, like any other body organ, is manifestation of Prana. And they being non-organ self of body, play critical role in well-being of body organs.

We can prevent cancer easily. Even cancer management is also less painful compare to modern chemo and radiation torture.

Three fundamental source of Prana for restoration

  1. Raw Prana from the Sun
  2. Churned Prana from Desi cow’s milk and ghee
  3. Food grown on the soil replenished by raw and churned prana (Sun light, cow dung, urine, milk, butter milk)

GUTBacteria


Research


Gut Bacteria Determine Speed of Tumor Growth in Pancreatic Cancer

https://nyulangone.org/press-releases/gut-bacteria-determine-speed-of-tumor-growth-in-pancreatic-cancer

The population of bacteria in the pancreas increases more than a thousand fold in patients with pancreatic cancer, and becomes dominated by species that prevent the immune system from attacking tumor cells.

These are the findings of a study conducted in mice and in patients with pancreatic ductal adenocarcinoma (PDA), a form of cancer that is usually fatal within two years. Led by researchers at NYU School of Medicine, Perlmutter Cancer Center, and NYU College of Dentistry, the study published online March 22 in Cancer Discovery, a journal of the American Association for Cancer Research (AACR).

Specifically, the study found that removing bacteria from the gut and pancreas by treating mice with antibiotics slowed cancer growth and reprogrammed immune cells to again “take notice” of cancer cells. Oral antibiotics also increased roughly threefold the efficacy of checkpoint inhibitors, a form of immunotherapy that had previously failed in pancreatic cancer clinical trials, to bring about a strong anti-tumor shift in immunity.

Experiments found that in patients with PDA, pathogenic gut bacteria migrate to the pancreas through the pancreatic duct, a tube that normally drains digestive juices from the pancreas into the intestines. Once in the pancreas, this abnormal bacterial mix (microbiome) gives off cellular components that shut down the immune system to promote cancer growth, say the authors.

Soil Health Card is useless without गौ आधारित खेती (Cow-based farming)

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SoilMicrobesCarbon

American university proclaims:

“With more than 7 billion microorganisms in the soil, it’s no surprise we still have a lot to learn about them and their impact on the environment. “Consequently, the activity of microorganisms in soil has the potential to alleviate or worsen climate change, so we need to form predictions regarding their activities.”

Do you think without Gau mata, one can achieve this?

Remember, I often share here that

Gau out = Desert In
Desert In = Desert Religion In (Islam/Christianity)

Soil health card may be good way to track soil nutrients but it is useless if you cannot understand value of cow in maintaining soil health. Soil health does not only mean NPK! Or Organic matter. It mean Prana! and only Gau mata can provide Prana!!

Not only carbon cycle, Gau mata has potential to stabilize all natural cycles!! She is medium via which we should embrace primordial prana i.e. Sun


Research


WVU researcher uncovers influence of microorganisms on soil carbon storage

With more than 7 billion microorganisms in the soil, it’s no surprise we still have a lot to learn about them and their impact on the environment. A West Virginia University researcher is uncovering critical information about these tiny organisms under our feet, which although small, can have a huge impact on the environment.

Ember Morrissey, assistant professor of environmental microbiology in the Davis College of Agriculture, Natural Resources and Design, received a $150,000 grant from National Science Foundation’s Division of Environmental Biology’s Early-concept Grants for Exploratory Research program, known as EAGER, to increase understanding of the behavior of microorganisms in the soil to provide descriptions of microbial function that currently aren’t available.

Morrissey’s research will lay the groundwork needed to figure out how soil can be managed to address environment-related processes and issues, including global warming and climate change.

Of particular interest for Morrissey and other researchers is the ability to formulate more precise predictions of microorganisms’ carbon cycling, or how they use and create carbon, a key to combatting climate change.

“Soil stores a large fraction of the earth’s carbon – actually more carbon than the atmosphere and biosphere combined,” Morrissey explained. “Microorganisms break down and consume this carbon as they live and grow, converting it into the greenhouse gas carbon dioxide.

“Consequently, the activity of microorganisms in soil has the potential to alleviate or worsen climate change, so we need to form predictions regarding their activities.”

https://wvutoday.wvu.edu/stories/2017/01/17/wvu-researcher-uncovers-influence-of-microorganisms-on-soil-carbon-storage

 

Local Food, Mother’s diet and Infant’s milk microbes

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Local Food
Even closed door medical conferences across India cherish importance of local diet influence, society follow market and media and enjoy global diet. One of the fundamental error in selection of food is to select food for taste and urge to taste non-local food.
 
For example: It is perfectly ok to eat Idli-Sambhar in Kerala but having same every day in Gujarati home living in Gujarat?
 
It is perfectly ok to eat apple in Himachal but having same in hot and humid Gujarat summer?
My common sense suggest to prefer only local diet over non-local taste-lust food selection.
 
For would-be mothers, it is important to maintain local diet if they wish their breast-feeding. What you eat, decides GUT microbes and in turn pass on legacy to newborn babies via breast-milk!
Your local diet is the immunity for your kid. During and after breast-feeding. And not the packaged processed food!
Educate mothers around you and help building strong Nation via strong future geneations.
Here is the interesting study looking to localization of GUT microbes of breast-feeding mothers’ GUT. It supports the hypothesis that there is no alternative of local diet. All healthy diet fads are marketing gimmick or at best, suitable to local population where the diet is showing results. What is good for pregnant mother in China, may not work for same in India!
———–
Research
——–

Bacterial Composition and Diversity in Breast Milk Samples from Mothers Living in Taiwan and Mainland China

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447776/

Human breast milk is widely recognized as the best source of nutrients for healthy growth and development of infants; it contains a diverse microbiota. Here, we characterized the diversity of the microbiota in the breast milk of East Asian women and assessed whether delivery mode influenced the microbiota in the milk of healthy breast-feeding mothers. We profiled the microbiota in breast milk samples collected from 133 healthy mothers in Taiwan and in six regions of mainland China (Central, East, North, Northeast, South, and Southwest China) by using 16S rRNA pyrosequencing. Lactation stage (months postpartum when the milk sample was collected) and maternal body mass index did not influence the breast milk microbiota. Bacterial composition at the family level differed significantly among samples from the seven geographical regions. The five most predominant bacterial families were Streptococcaceae(mean relative abundance: 24.4%), Pseudomonadaceae (14.0%), Staphylococcaceae (12.2%), Lactobacillaceae (6.2%), and Oxalobacteraceae (4.8%). The microbial profiles were classified into three clusters, driven by Staphylococcaceae (abundance in Cluster 1: 42.1%), Streptococcaceae (Cluster 2: 48.5%), or Pseudomonadaceae (Cluster 3: 26.5%). Microbial network analysis at the genus level revealed that the abundances of the Gram-positive StaphylococcusStreptococcus, and Rothia were negatively correlated with those of the Gram-negative AcinetobacterBacteroidesHalomonasHerbaspirillum, and Pseudomonas. Milk from mothers who had undergone Caesarian section (C-section group) had a significantly higher abundance of Lactobacillus (P < 0.05) and a higher number of unique unclassified operational taxonomic units (OTUs) (P < 0.001) than that from mothers who had undergone vaginal delivery (vaginal group). These findings revealed that (i) geographic differences in the microbial profiles were found in breast milk from mothers living in Taiwan and mainland China, (ii) the predominant bacterial families StreptococcaceaeStaphylococcaceae, and Pseudomonadaceae were key components for forming three respective clusters, and (iii) a significantly greater number of unique OTUs was found in the breast milk from mothers who had undergone C-section than from those who had delivered vaginally.

Distinct Patterns in Human Milk Microbiota and Fatty Acid Profiles Across Specific Geographic Locations.

https://www.ncbi.nlm.nih.gov/pubmed/27790209

Conclusion

https://www.frontiersin.org/files/Articles/217349/fmicb-07-01619-HTML/image_m/fmicb-07-01619-g002.jpg
https://www.frontiersin.org/files/Articles/217349/fmicb-07-01619-HTML/image_m/fmicb-07-01619-g002.jpg

Our results demonstrate differences in the composition of lipids and microbiota in breast milk in different geographic regions and offer a new insight to the differences in development of gut microbiota in infants in different geographic areas. The impact of mode of delivery on milk microbiota composition appears to be even more important within all geographical regions. Furthermore, our study shows distinct association between fatty acid composition and individual microbiota in breast milk, suggesting important role of lipids in shaping the microbial profile which likely one important factor influencing the infant gut microbiota development.

Microbial Community(प्राणमय कोष) controls Gene expression : Not genes, epigenetic!

http://www.cell.com/cms/attachment/2079859016/2071400130/fx1.jpg
http://www.cell.com/cms/attachment/2079859016/2071400130/fx1.jpg

Instead of medicine, why I suggest all friends to worship Surya and Hanuman! 🙂 It is the need of the hour as our Prana is being consumed daily rapidly by toxic environment, physical and mental.

So many dots can be connected by reading this research paper.

This is wonderful morning as I read this research. One more confirmation proof for my theory that it is प्राणमय कोष that actually influences body and not the genes!!

Entire Genome project is pseudo-science of last century! And so GMO crops! Yes, this is tall claim and against the waves but it is the reality! 🙂

प्राणमय कोष is our immunity. It is our cellular intelligence. It is the one that manifests and govern cell-formation. It is the one that manifests cells with individual identity i.e. microbes rather than collective identity i.e. Body organ cell like skill cell, liver cell or neuron.

It is not just me! I know couple of researchers confirming the same fact and working hard to find more and more epigenetic links!

Our food, our thoughts – all influence our well-being. Genes are actually controlled by them!!

It is not genes, it is epigenetic!

In our guts, and in the guts of all animals, resides a robust ecosystem of microbes known as the microbiome. Consisting of trillions of organisms — bacteria, fungi and viruses — the microbiome is essential for host health, providing important services ranging from nutrient processing to immune system development and maintenance.

Now, in a study comparing mice raised in a “germ free” environment and mice raised under more typical lab conditions, scientists have identified yet another key role of the microbes that live within us: mediator of host gene expression through the epigenome, the chemical information that regulates which genes in cells are active.

Writing online Nov. 23 in the journal Molecular Cell, a team of researchers from the University of Wisconsin–Madison describes new research helping tease out the mechanics of how the gut microbiome communicates with the cells of its host to switch genes on and off. The upshot of the study, another indictment of the so-called Western diet (high in saturated fats, sugar and red meat), reveals how the metabolites produced by the bacteria in the stomach chemically communicate with cells, including cells far beyond the colon, to dictate gene expression and health in its host.


Research


Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues

http://dx.doi.org/10.1016/j.molcel.2016.10.025

Highlights

  • Gut microbiota alter host histone acetylation and methylation in multiple tissues
  • Western diet suppresses microbiota-driven SCFA production and chromatin effects
  • SCFAs recapitulate microbiota-driven chromatin and transcriptional effects

Summary

Histone-modifying enzymes regulate transcription and are sensitive to availability of endogenous small-molecule metabolites, allowing chromatin to respond to changes in environment. The gut microbiota produces a myriad of metabolites that affect host physiology and susceptibility to disease; however, the underlying molecular events remain largely unknown. Here we demonstrate that microbial colonization regulates global histone acetylation and methylation in multiple host tissues in a diet-dependent manner: consumption of a “Western-type” diet prevents many of the microbiota-dependent chromatin changes that occur in a polysaccharide-rich diet. Finally, we demonstrate that supplementation of germ-free mice with short-chain fatty acids, major products of gut bacterial fermentation, is sufficient to recapitulate chromatin modification states and transcriptional responses associated with colonization. These findings have profound implications for understanding the complex functional interactions between diet, gut microbiota, and host health.

Increasing Eye diseases? High fat-High Sugar diet and Microbes

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==================
HIGH fat diet => Eye degeneration
==================

csm_20161114_intestin-bacteries_f4d9dbc3c1

Most critical organ of the body besides Heart is GUT and not brain! Sadly, we treat it like a gutter!

In past 5 years, I have shared almost 100 researches connecting GUT microbes with different bodily phenomenons.

This research is addition to it.

GUT Microbes affects major Eye diseases!

In Hindu Dharma, we worship two God(s) daily. Hanuman and Ganesh. They are always there in any temples.

They represent Muladhara. The Gut Protectors.


Research


Microbes in your gut influence major eye disease

Bacteria in your intestines may play an important role in determining if you will develop blinding wet Age-related Macular Degeneration (AMD).

http://nouvelles.umontreal.ca/en/article/2016/11/15/microbes-in-your-gut-influence-major-eye-disease/
“Our study suggests that diets rich in fat alter the gut microbiome in a way that aggravates wet AMD, a vascular disease of the aging eye. Influencing the types of microbes that reside in your gut either through diet or by other means may thus affect the chances of developing AMD and progression of this blinding disease”, says Dr Sapieha. Professor Sapieha holds the Wolfe Professorship in Translational Vision Research and a Canada Research Chair in retinal cell biology. The study was funded by the Foundation Fighting Blindness, the Canadian Institutes of Health Research, and thr Fond de Recherche en Ophthalmologie de l’Université de Montreal.

Cospeciation : Coevolution, Gut Microbes and role of Prana

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Conspeciation
This science paper confirms eternity of प्राण | Bacteria are manifestation of वैश्विक प्राण | So, not all Gut bacteria are acquired at birth! Some of them followed eternal journey with us!! And they depend upon host lineages!
 
“Gut bacteria therefore are not simply acquired from the environment, but have coevolved for millions of years with hominids to help shape our immune systems and development.”
 
Like how Prana drives growth of body from conception to birth to the youth, same Prana manifest microbial bacteria in GUT as per the need !
 
Our gutter-satisfying eating habits, medications ruin the legacy received from lineages!
 
“The evolutionary origins of the bacterial lineages that populate the human gut are unknown. Here we show that multiple lineages of the predominant bacterial taxa in the gut arose via cospeciation with humans, chimpanzees, bonobos, and gorillas over the past 15 million years. Analyses of strain-level bacterial diversity within hominid gut microbiomes revealed that clades of Bacteroidaceae and Bifidobacteriaceae have been maintained exclusively within host lineages across hundreds of thousands of host generations. Divergence times of these cospeciating gut bacteria are congruent with those of hominids, indicating that nuclear, mitochondrial, and gut bacterial genomes diversified in concert during hominid evolution. This study identifies human gut bacteria descended from ancient symbionts that speciated simultaneously with humans and the African apes.”
 

Cospeciation of gut microbiota with hominids

http://science.sciencemag.org/content/353/6297/380

Human-microbiota coevolution

The bacteria that make their home in the intestines of modern apes and humans arose from ancient bacteria that colonized the guts of our common ancestors. Moeller et al. have developed a method to compare rapidly evolving gyrB gene sequences in fecal samples from humans and wild chimpanzees, bonobos, and gorillas (see the Perspective by Segre and Salafsky). Comparison of the gyrB phylogenies of major bacterial lineages reveals that they mostly match the apehominid phylogeny, except for some rare symbiont transfers between primate species. Gut bacteria therefore are not simply acquired from the environment, but have coevolved for millions of years with hominids to help shape our immune systems and development.

Muladhara(मूलाधार) and Cancer : Prevent and Cure

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MicrobesCancer

Tvam muladhara sthitosi nityam |
त्वं मूलाधार स्थितोऽसि नित्यं।
Lord Ganesha! You always dwell in muladhara chakra!

मूलाधार : शक्ति Center near Gut & anus : Abode of मरुत गण (Microbes) and their leader गणपति

It does not only control microbes in GUT but of entire body.

He is the lord of muladhara chakra. In other words, he rules our microbial flora (मरुत गण) and make sure only body-friendly मरुत गण resides in the abode.

मरुत गण (Microbes) : गण पति (Ganesha) : गण (Citizens) & पति (Protector) live together @ Muladhara

Awakening गण पति शक्ति is critical for maintaining health (which is critical for self-realization). Only he can protect and act as gatekeeper of Muladhara (Gut) so that body is kept protected from pathogens & aasuri shakti.

Here are two interesting researchers focuses on Muladhara for cancer-cause and cancer recovery.


Research


Cleveland Clinic Researchers Find Link Between Bacterial Imbalances and Breast Cancer

In a newly published study, Cleveland Clinicresearchers have uncovered differences in the bacterial composition of breast tissue of healthy women vs. women with breast cancer. The research team has discovered for the first time that healthy breast tissue contains more of the bacterial species Methylobacterium, a finding which could offer a new perspective in the battle against breast cancer.

Bacteria that live in the body, known as the microbiome, influence many diseases.

Most research has been done on the “gut” microbiome, or bacteria in the digestive tract. Researchers have long suspected that a “microbiome” exists within breast tissue and plays a role in breast cancer but it has not yet been characterized. The research team has taken the first step toward understanding the composition of the bacteria in breast cancer by uncovering distinct microbial differences in healthy and cancerous breast tissue.

“To my knowledge, this is the first study to examine both breast tissue and distant sites of the body for bacterial differences in breast cancer,” said co-senior author Charis Eng, M.D., Ph.D., chair of Cleveland Clinic’s Genomic Medicine Institute and director of the Center for Personalized Genetic Healthcare. “Our hope is to find a biomarker that would help us diagnose breast cancer quickly and easily.  In our wildest dreams, we hope we can use microbiomics right before breast cancer forms and then prevent cancer with probiotics or antibiotics.”

Published online in Oncotarget on Oct. 5, 2017, the study examined the tissues of 78 patients who underwent mastectomy for invasive carcinoma or elective cosmetic breast surgery. In addition, they examined oral rinse and urine to determine the bacterial composition of these distant sites in the body.

newsroom.clevelandclinic.org/2017/10/05/cleveland-clinic-researchers-find-link-between-bacterial-imbalances-and-breast-cancer/

Good-guy bacteria helps in cancer therapies

Researchers found he had the beneficial gut bacteria and suspect this microbiome contributed to the outcome. As a group, patients who responded well to the immunotherapy had three specific bacteria:

  • Bacteroides thetaiotaomicron
  • Faecalibacterium prausnitzii
  • Holdemania filiformis

All three are common normal flora in the human intestinal tract.

After identifying the link, researchers looked for a potential reason for the association between the helper bacteria and immunotherapy effectiveness. “Is it something the bacteria are making? We examined metabolites in these subjects and found the strongest correlation between anacardic acid, present in cashews and mangoes, and the beneficial bacteria,” Dr. Koh said.

Researchers plan to follow up on the current research, which appears in the journal Neoplasia, with larger clinical studies.

http://www.utsouthwestern.edu/newsroom/articles/year-2017/bacteria-immunotherapy-koh.html

 

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