Microbes

Microbes

Heart Failure starts with Gut (मूलाधार) : Worship गणेश

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GUT bacteria and Heart failure
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Heart Ganesh

I am not microbiologist but हनुमान & गणेश भक्त. And they give enough hints about the गण they protect for me within this body-universe.

I repeat almost daily and urge friends to take care of GUT by proper diet, surya Namaskar.

Area from GUT to Navel – very critical for existence. Protect it.

गणपति resides in GUT area . And to worship him, we generally keep fast. Fasting clean the GUT and transforms it from GUTTER into Heaven. So clean GUT means right decisions, right actions and in real sense गणेश acts as विध्नहर्ता.

During monsoon, our digestive power remains very low and so there are high chances that GUT remains polluted. So just when the monsoon is on the verge of end, we worship गणेश for 10 days.


Research


Heart failure is associated with loss of important gut bacteria

https://dzhk.de/en/news/latest-news/article/heart-failure-is-associated-with-loss-of-important-gut-bacteria/

“In the gut of patients with heart failure, important groups of bacteria are found less frequently and the gut flora is not as diverse as in healthy individuals. Data obtained by scientists of the German Centre for Cardiovascular Research (DZHK) provide valuable points of departure for understanding how gut colonisation is associated with the development and progress of heart failure.”

Influential factors: diet, medication, smoking

“Of course, other factors also affect the composition of our gut bacteria. We know that the gut flora of a vegan who starts eating meat changes within three days”, explains associate professor Dr. Mark Lüdde of the University Hospital Schleswig-Holstein, Campus Kiel. For this reason, we asked the Kiel-based researchers of dietary habits beforehand. Individuals with an extreme diet, such as a vegan diet, were not allowed to participate in their study. Instead, they chose individuals with a standard diet comprising both meat and vegetables for both groups.

In addition to diet, medication also affect the gut flora. It was, therefore, important that the control group also took medicinal products that patients with heart failure must take routinely. Antibiotics could not have been administered for at least three months prior. Smokers were also included in both groups. All participants were from the same region and were the same age; gender distribution and BMI were equal in both groups.

Consequence or cause of the disease?

The observed pattern of the reduced genera and families of bacteria seems very characteristic of heart failure, which is why these results may be new points of departure for therapies. The differences between healthy individuals and those with heart failure, thus, came about mainly through the loss of bacteria of the genera Blautia and Collinsella, as well as two previously unknown genera that belong to the families Erysipelotrichaceae and Ruminococcaceae. 

The Gut, the Heart, and TMAO

Here’s how it works: When people ingest certain nutrients, such as choline (abundant in red meat, egg yolks, and dairy products) and L-carnitine (found in red meat as well as some energy drinks and supplements), the gut bacteria that break it down produce a compound called trimethylamine (TMA). The liver then converts TMA into the compound, trimethylene N-oxide (TMAO).

The trouble with TMAO is that data show high levels contribute to a heightened risk for clot-related events such as heart attack and stroke—even after researchers take into account the presence of conventional risk factors and markers of inflammation that might skew the results. In their most recent analysis, scientists showed that high blood levels of TMAO were associated with higher rates of premature death in a group of 2235 patients with stable coronary artery disease. Those found to have higher blood levels of TMAO had a four-fold greater risk of dying from any cause over the subsequent five years.

The implications are intriguing. Taken together, the new studies suggest that positively altering the gut microbiota may help to reduce damage to blood vessels, resulting in a stronger cardiovascular system, and they point to targets for potential new heart disease therapies.

The Gut, the Heart, and TMAO

 

Why Body Massage in Winter? Skin bacteria could protect against disease

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bacteria

There are more and more examples of the ways in which we can benefit from our bacteria. According to researcher Rolf Lood from Lund University in Sweden, this is true for the skin as well. He has shown that the most common bacteria on human skin secrete a protein which protects us from the reactive oxygen species thought to contribute to several skin diseases. The protein has an equally strong effect on dangerous oxygen species as known antioxidants such as vitamin C and vitamin E.

Dry skin harbors more variety of bacteria including reactive oxygen species.

As per modern microbiology, highest diversity (not numbers) of bacteria resides on the dry areas of the skin.

What are the driest part?

Our hands and our buttocks.

Winter + Vata Derangement => Skin Dryness => Prana (प्राण) is consumed vigorously to protect the skin => more bacteria on skin for cleaning job of cellular debris. => Low Prana => Flu

Replenish Prana for skin by frequent hand-wash. Do body massage during winter (Sesame oil).

Easy?


Research


Skin bacteria could protect against disease

http://www.lunduniversity.lu.se/article/skin-bacteria-could-protect-against-disease

The skin bacterium is called Propionibacterium acnes.

“The name originates from the fact that the bacterium was first discovered on a patient with severe acne. But whether it causes acne is uncertain – it may have been present merely because it is so common”, says Rolf Lood at the Department of Clinical Sciences in Lund.

He has discovered that the “acne bacterium” secretes a protein called RoxP. This protein protects against what is known as oxidative stress, a condition in which reactive oxygen species damage cells. A common cause of oxidative stress on the skin is UV radiation from the sun.

“This protein is important for the bacterium’s very survival on our skin. The bacterium improves its living environment by secreting RoxP, but in doing so it also benefits us”, explains Rolf Lood.

Oxidative stress is considered to be a contributing factor in several skin diseases, including atopic dermatitis, psoriasis and skin cancer.

Since Propionibacterium acnes is so common, it is present in both healthy individuals and people with skin diseases. According to Rolf Lood, however, people have different amounts of the bacterium on their skin, and it can also produce more or less of the protective protein RoxP.

This will now be further investigated in both patients and laboratory animals by Lood and his team. The human study will compare patients with basal cell carcinoma, a pre-cancerous condition called actinic keratosis and a healthy control group. The study will be able to show whether there is any connection between the degree of illness and the amount of RoxP on the patient’s skin.

The study on laboratory animals will also examine whether RoxP also functions as protection. Here, mice who have been given RoxP and others who have not will be exposed to UV radiation. The researchers will then observe whether the RoxP mice have a better outcome than those who were not given the protective protein.

“If the study results are positive, they could lead to the inclusion of RoxP in sunscreens and its use in the treatment of psoriasis and atopic dermatitis”, hopes Rolf Lood. His research findings have recently been published in an article in the Nature journal Scientific Reports.

A novel enzyme with antioxidant capacity produced by the ubiquitous skin colonizer Propionibacterium acnes

http://www.nature.com/articles/srep36412#auth-4

The role of the skin microbiota in human health is poorly understood. Here, we identified and characterized a novel antioxidant enzyme produced by the skin microbiota, designated RoxP for radical oxygenase of Propionibacterium acnes. RoxP is uniquely produced by the predominant skin bacterium P. acnes, with no homologs in other bacteria; it is highly expressed and strongly secreted into culture supernatants. We show that RoxP binds heme, reduces free radicals, and can protect molecules from oxidation. Strikingly, RoxP is crucial for the survival of P. acnes in oxic conditions and for skin colonization of P. acnes ex vivo. Taken together, our study strongly suggests that RoxP facilitates P. acnes’ survival on human skin, and is an important beneficial factor for the host-commensal interaction. Thus, RoxP is the first described skin microbiota-derived mutualistic factor that potentially can be exploited for human skin protection.

 

Why home-based fermented food? Link to Acidity

The Pink Acidity Medicine Src: http://goo.gl/ycnG8x
The Pink Acidity Medicine
Src: http://goo.gl/ycnG8x

In last post, I talked about importance of bacteria in controlling our mood/mental state.

This[1] interesting article supports the hypothesis I presented about eating ONLY home-made dahi/butter milk/yogurt (to avoid alien bacteria of alien environment i.e. shop/factory where dahi is prepared in mass). It also suggests another hypothesis of having Panchmrit prepared from all unrefined, unprocessed raw milk, jaggery, sugar and honey.

More processed food you eat, more alien food you eat (Food prepared in alien environment i.e. restaurants), frequent travelling you do (so eating outside food frequently) and more acidity you suffer from.

The researchers found that scavengers, or species that eat food at high risk of microbial contamination, have more acidic stomachs. This acidity allows the stomach to act as a filter, effectively controlling which microbes can pass through the stomach to the gut.

Passing stomach acidity is very essential for probiotic food. Most probiotic food available in market fail here. It only helps in increasing acidity of the stomach.

An analysis of data on stomach acidity and diet in birds and mammals suggests that high levels of stomach acidity developed not to help animals break down food, but to defend animals against food poisoning. The work raises interesting questions about the evolution of stomach acidity in humans, and how modern life may be affecting both our stomach acidity and the microbial communities that live in our guts.

Antacids is not a solution. It is actually counter-health solution. Right solution is to avoid eating at unknown food-joints, at unknown places. Avoid highly processed food full of chemicals.

Pathology-Low-Acid-Level-Diseases
Pathology-Low-Acid-Level-Diseases

1) If you start cooking for self, you will never need acidity regulators!acidity regulators are against the innate nature of stomach! Never take them! They worsen the stomach working.
2) Take good care of selecting and preparing probiotic food.
3) Avoid outside food and travelling as much as possible
4) Avoid non-veg diet if you are living in terrain where plant based diet is available.

Take care. Never seek easy short-sighted solutions.

The Evolutionary Link Between Diet and Stomach Acidity

[1] Reference: https://news.ncsu.edu/2015/07/beasley-acid-2015/

Diet and Stomach Acidity
Diet and Stomach Acidity

Gastric acidity is likely a key factor shaping the diversity and composition of microbial communities found in the vertebrate gut. We conducted a systematic review to test the hypothesis that a key role of the vertebrate stomach is to maintain the gut microbial community by filtering out novel microbial taxa before they pass into the intestines. We propose that species feeding either on carrion or on organisms that are close phylogenetic relatives should require the most restrictive filter (measured as high stomach acidity) as protection from foreign microbes. Conversely, species feeding on a lower trophic level or on food that is distantly related to them (e.g. herbivores) should require the least restrictive filter, as the risk of pathogen exposure is lower. Comparisons of stomach acidity across trophic groups in mammal and bird taxa show that scavengers and carnivores have significantly higher stomach acidities compared to herbivores or carnivores feeding on phylogenetically distant prey such as insects or fish. In addition, we find when stomach acidity varies within species either naturally (with age) or in treatments such as bariatric surgery, the effects on gut bacterial pathogens and communities are in line with our hypothesis that the stomach acts as an ecological filter. Together these results highlight the importance of including measurements of gastric pH when investigating gut microbial dynamics within and across species

Cow Milk and Prebiotic Medium

Everyone is talking about probiotic food nowadays. Sadly, this awareness is mostly limited to two jargon 1) Probiotic 2) Prebiotic

Let us try to understand, what they are!

Probiotics are live microorganisms that live in gastrointestinal (GI) tract and are beneficial for their hosts and prevent certain diseases.

Prebiotics are non‐digestible food ingredients that beneficially affect the host by selectively stimulating the growth and activity of probiotic bacteria in the colon. All dietary prebiotics and/or dietary fiber provide the physiological and beneficial effects and, therefore, are considered as essential nutrients.

In post antibiotic obsession era, everyone is now praising microbes. But no one is talking about microbes sustenance medium. Healthy bacteria survives when their environment is potent to provide them continuous nutrition.

Prebiotic – this is where desi zebu cattle milk plays wonder. It is potent prebiotic.

Probiotic benefits
Probiotic benefits

गौर्धयति मरुतां शरवस्युर्माता मघोनाम |
युक्ता वह्नी रथानाम || (ऋगवेद ८-९४-१)

गौ माता दूध पिलाती है, उस दूधसे संतृप्त हो मरुत वीर रथसंचालक (वेगवान) बनते है|

As you read translation, only desi Gau mata’s A2 milk is potent enough to provide them driving force ( रथसंचालक). If such potent medium is not provided (like many Vegan friends find alternative solution in Vegan Dahi made up using coconut or badam or any other nuts) to them, health bacteria may die soon, before reaching to their destination i.e. GUT. Dead probiotic means more danger for digestive track! More efforts to clean the track! Acidity! Ulcer!

Probiotics promote gut health through stimulation, rather than suppression, of the innate immune system. Our first lines of defense are digestive chemistry and innate immunity.

For a probiotic to work it must arrive alive in the colon. They arrive alive only when they have enough food while travelling and are acid proof (Protected from gastric acids). It has been recommended that food containing probiotic bacteria should contain at least 10^6 live micro organisms per g or mL at the time of consumption to have protective effects such as maintenance of normal intestinal micro flora, enhancement of the immune system, reduction of lactose intolerance and anti-cancer activity.
Along with that probiotics should resist the natural barrier of high acidity and bile content in the gastrointestinal tract (GIT) and show their survivability and activity in the colon.

Only Desi Gau milk based fermentation has both powers. (Do your experiments if you have doubts).

Which Desi Gau milk?

या शर्धाय मारुताय सवभानवे शरवो.अम्र्त्यु धुक्षत |
या मर्ळीके मरुतां तुराणां या सुम्नैरेवयावरी || Rugved – Book 6 – Hymn 48 – Verse 12

Translation
Gau who provides immortal nectar milk for powerful self-illuminating Marut(s); the one who provides happiness/comfort to swift-footed(quick runner) Marut(s), that divine Gau comes to your home only by glorious efforts and actions.

Gau mata can give such nectar milk only when she is worshiped by brave men doing selfless glorious acts for society. Gau seva for selfish motives is not desirable. So if you purchase milk from professional gau shala, you will still will not avail full benefits of nectar. You first need to worship Gau mata whose milk you want to avail. Without worship, you cannot connect with her. Without connecting with her, it is not possible to receive her blessings.

Krishna with Gaia
Krishna with Gaia

Krishna is Krishna due to Gau Mata Seva and Worship. Do we follow him? 🙂

Fundamental fallacy in dairy model is: disconnect between mata and son. Mother can foster best prasad (milk, urine, dung), only when she is taken care best! Factory model of dairy don’t yield benefits described here.

 

Vitamin B12 Deficiency, GUT and Muladhara

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Yesterday was harsh day of this season. Heavy rain, humid, and extreme heat. My friend and I, working on critical task, felt exhausted. Dehydrated.

Friend suggested :”I think it is again Vitamin B12 deficiency! I think I will need injections again!”

I wondered. How a simple season driven exhaustion is turned into deficiency! 🙁

There were two things at play for both of us. 1) Stress induced non-healthy GUT 2) lack of healthy food for days.

Solution is to take rest. Worship Ganesha and eat healthy season driven food!

 

B12 Eyewash
B12 Eyewash

Modern medicine has reduced wholesome food into supplement status symbols.

Oh, B12 ? Take injections!
Oh Vit A? Take this supplement!

This is nothing but eyewash. Unless we correct our GUT, there is no hope for malnutrition.Malnutrition may manifest as either obesity or undernutrition. Accumulating evidence suggests that the gut microbiota plays an important role in the harvest, storage, and expenditure of energy obtained from the diet.

Gut Health
Gut Health

One person might have stronger nerves than another because she has a better stock of vitamin B–producing bacteria. Another person might be able to deal easily with bit of bread mold eaten by mistake. Yet another might have a tendency to gain weight because the “chubby” bacteria in his gut feed him a bit too willingly. Science is just beginning to understand that each of us is an entire ecosystem.

You take all costly B-12 injections or Vitamin A supplement or Vitamin C but if your GUT is not healthy, they are garbage and will be purged within 72 hrs via urine and stool!

There is no shortcut for healthy life. Stop nonsensical torture on body first. Stop all processed acidic food so that bacteria have chance to get flourished in you GUT. Then stop stressful events in life. Late night parties, tongue-lust driven non-seasonal food – stop it if you really want your B12 injections to work.

Above all physical nutrition, health is all mental. To correct your mental stress and linked sick GUT, this is best season. गणपति is protector of GUT. As per Tantra-Shashtra, गणपति lives in Muladhara, an energy center near GUT. It is your mind that helps प्राणमय शरीर (cellular intelligence) to form health अन्नमय शरीर (physical body) (Do not ask proof. Modern proof-based science cannot swim in this sea of knowledge at this moment). Experiment! Does not matter if you are an atheist! Or follow any other religion. गणपति is eternal, beyond religious boundaries.

Worship and surrender to गणपति. That is the beginning of the yearly healthy GUT.

ॐ गणेशाय नमः |

Muladhara Protector
Muladhara Protector

Research


Bacteria as vitamin suppliers to their host: a gut microbiota perspective.

http://www.ncbi.nlm.nih.gov/pubmed/22940212

Food-related lactic acid bacteria (LAB) as well as human gut commensals such as bifidobacteria can de novo synthesize and supply vitamins. This is important since humans lack the biosynthetic capacity for most vitamins and these must thus be provided exogenously. Although vitamins are present in a variety of foods, deficiencies still occur, mainly due to malnutrition as a result of insufficient food intake and because of poor eating habits. Fermented milks with high levels of B-group vitamins (such as folate and riboflavin) can be produced by LAB-promoted and possibly bifidobacteria-promoted biosynthesis. Moreover, certain strains of LAB produce the complex vitamin cobalamin (or vitamin B12). In this review, fermented foods with elevated levels of B-group vitamins produced by LAB used as starter cultures will be covered. In addition, genetic abilities for vitamin biosynthesis by selected human gut commensals will be discussed.

Vitamin B12 synthesis by human small intestinal bacteria.

http://www.ncbi.nlm.nih.gov/pubmed/7354869

In man, physiological amounts of vitamin B12 (cyanocobalamin) are absorbed by the intrinsic factor mediated mechanism exclusively in the ileum. Human faeces contain appreciable quantities of vitamin B12 or vitamin B12-like material presumably produced by bacteria in the colon, but this is unavailable to the non-coprophagic individual. However, the human small intestine also often harbours a considerable microflora and this is even more extensive in apparently healthy southern Indian subjects. We now show that at least two groups of organisms in the small bowel, Pseudomonas and Klebsiella sp., may synthesise significant amounts of the vitamin.

Effects of Gut Microbes on Nutrient Absorption and Energy Regulation

Malnutrition may manifest as either obesity or undernutrition. Accumulating evidence suggests that the gut microbiota plays an important role in the harvest, storage, and expenditure of energy obtained from the diet. The composition of the gut microbiota has been shown to differ between lean and obese humans and mice; however, the specific roles that individual gut microbes play in energy harvest remain uncertain. The gut microbiota may also influence the development of conditions characterized by chronic low-level inflammation, such as obesity, through systemic exposure to bacterial lipopolysaccharide derived from the gut microbiota. In this review, the role of the gut microbiota in energy harvest and fat storage is explored, as well as differences in the microbiota in obesity and undernutrition.

 

Probiotic food, Rama, Ravana and Dussehra

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Probiotic food, Rama, Ravana and Dashera
Probiotic food, Rama, Ravana and Dashera

In all ages, we need Ravana to rise so that we realize value of Rama (Life force in us). The faithful Vanar Sena (Microbial world who is known as मरुत गण (सेना) in Sanskrit and their leader मरुतनंदन or मारुतिनंदन हनुमान) of Rama, make sure that Rama wins over Ravana in all ages and times.
वानरसेना or मरुत गण helps Rama to re-establish life force in Lanka (Gut in our body) so that life can survive.

Antibiotics, pesticides, hormones, X-ray, CT-Scan, Irradiation of food for long shelf life, GM food are 10 faces of modern Ravana of our times. It has helped us to re-establish value of Rama and वानरसेना in our life. You see people talking about probiotic food often now in social circles (online and real life)

This is important time when we re-establish Rama Rajya in our body by wiping out Ravana (Antibiotics and alike toxins) with the help of वानरसेना (Microbes).

So it is our critical duty of train वानरसेना and help them realize their real potential.

How?
By avoiding anti-microbe food. By taking pro-microbe food. By using Pro-microbe methods to grow food.

Who can help?
Gau mata -> Gobar, Ghee, Dahi, Milk, Urine = All are full of healthy microbes and potential breeding ground for microbes.

Almost all communities in India have some festival around the spring season that revolves around “stale food”. This overnight stale food is purposely kept at room temperature and often gets sour, but the custom is not to reheat the stale food and eat it for all meals the next day (शीतला सातम/શીતળા સાતમ in Gujarat). This has been a great way to introduce the body to the coming season’s probiotic as well as pathogenic microbes through overnight food. The probiotic bacteria help build good immunity, boosting gut flora, and the inoculation with pathogenic bacteria in small numbers prepares the immune system for seasonal illnesses by switching on the Immunoglobulin M protein, a basic antibody, as the first immune response.

Notably, this overnight meal is eaten on a day called Sheetalshashthi by Bengalis and around the same time of the year, by Marathis and Sindhis as well. It is supposed to bring immunity from small pox infections. MaaSheetala is considered the goddess who treats small pox and this ritualistic consumption of fermented food is interesting in this regard.
Sindhis call this festival Satam around the shrawan month and the stale food is called kanbo and includes fried fritters of the sweet and savoury variety. Mithila Brahmins also eat overnight stale daalpoori, kheer, sattu, badiyan (dried lentil cakes) and drink the extract of a herb called chirata, which is an immunity boosting agent. The association of this ritual in different communities with immunity is also notable.

Apart from the ritualistic consumption of probiotic foods, almost all communities in the country have something cooked or prepared regularly that helps build up probiotic flora. These are mostly the foods that are fermented with the expertise handed down through generations, involving recipes that are woven around the availability of some fresh produce, scarcity of some other in a particular geographic location.
The popular breakfast dish of puffed rice (murmura) or poha is good probiotic food too. The rice products are made after parboiling paddy and sun drying it for a few hours before either beating it flat to make poha or roasting it in sand to get puffed rice. The rice ferments partially after parboiling and retains the microbial flora, getting superior food value as well as partially digested proteins and carbohydrates.

At the end of monsoon season, we celebrate victory of Rama over Ravana on Dashera (meaning: You survived entire year as healthy being with the help of वानरसेना or Microbial world . Now it is easy for you realize value of your festivals. Such a great epic poem which can give these hints about life! Should we not teach this to kids at school? Ramayana and Mahabharat are not for one religion. They are books of humanity. Real Indian, irrespective of religion, should read Ramayana and Mahabhrara to their kids.

To celebrate real Dashera, we must stop anti-microbe practices in society. Stop antibiotics. Stop floor cleaners. Stop Coca cola. Stop chemically processed food. Stop GM seeds. Stop pesticides. Protect Gau mata. Promote Gau-prasad (Gobar,Urine, Dahi, milk, ghee) based farming. Include live pro-biotic food in diet. Enjoy Dashera with really healthy life force (Rama), by killing Ravana in environment, within body and in universe.

Read this further:

http://www.downtoearth.org.in/news/ferment-food-for-the-gut-45574

 

The human milk microbiota

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yong-breastmilk-1200

So far, we were told that Mother’s milk is sterile. Absolutely pure.
And with this image, we also strive for Dairy milk. Pasteurized! Sterile. No bacteria at all!

That is the level of modern scientific temper we are proud of. 🙂 And investing heavily so that our kids are groomed under it. 🙂 (This does not mean I do not respect science and her achievements. Just a direction and outlook to look at nature is wrong).

In Ayurvedic understanding, no organism is harmful. Everyone is doing their job (or following their Dharma). Bacteria in milk are necessary. They are their to help the consumer of the milk.

figure-1-potential-mechanisms-of-the-human-milk-microbiome-establishment-physiological

“Culture-dependent and -independent techniques have revealed the dominance of staphylococci, streptococci, lactic acid bacteria and bifidobacteria in this biological fluid, and their role on the colonization of the infant gut. These bacteria could protect the infant against infections and contribute to the maturation of the immune system, among other functions.”

It is high time we get rid of this germ-phobia. ASAP. Sooner the better.

The way mother’s milk helps infant, Gau milk helps adults.

On immediate basis, dairy milk should be replaced with raw milk from Gau shala where ethical practices are followed (Calf’s milk is not snatched. No hormone injections are used. Machines are not used for milking etc)


Research


The human milk microbiota: origin and potential roles in health and disease.

https://www.ncbi.nlm.nih.gov/pubmed/22974824

Human milk has been traditionally considered sterile; however, recent studies have shown that it represents a continuous supply of commensal, mutualistic and/or potentially probiotic bacteria to the infant gut. Culture-dependent and -independent techniques have revealed the dominance of staphylococci, streptococci, lactic acid bacteria and bifidobacteria in this biological fluid, and their role on the colonization of the infant gut. These bacteria could protect the infant against infections and contribute to the maturation of the immune system, among other functions. Different studies suggest that some bacteria present in the maternal gut could reach the mammary gland during late pregnancy and lactation through a mechanism involving gut monocytes. Thus, modulation of maternal gut microbiota during pregnancy and lactation could have a direct effect on infant health. On the other hand, mammary dysbiosis may lead to mastitis, a condition that represents the first medical cause for undesired weaning. Selected strains isolated from breast milk can be good candidates for use as probiotics. In this review, their potential uses for the treatment of mastitis and to inhibit mother-to-infant transfer of HIV are discussed.

The Intestinal Microbiota ‘talk’ to gut bacteria to boost immune system

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No infection is bad. Infection response is good or bad. Your survival depends upon how you respond. Killing microbes, killing worms is no way right response. As shared in this research, worms are actually having serious talk with our immune system. Our killing hampers communication and so there will be another spell of infection and the vicious cycle goes on,. Ideal response is to make this talk efficient and while the talk is going on, maintain bodily प्राण. And the response is based on our innate energy layer i.e. प्राणमय कोष (प्राणिक शरीर). Richer the प्राण, better the response.

Otherwise, no infection is bad. All infections have goal/purpose, designed by nature, to help the host organisms to emerge as more strongly typed identities (Self-realization, Ego, “I”-ness – whatever way you understand)

Since children are growing and their I-ness is developing, they frequently get infections.

Worms boost Immunity
Worms boost Immunity

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Researchers have discovered how intestinal worm infections cross-talk with gut bacteria to help the immune system. Intestinal worms infect over 2 billion people across the world, mostly children, in areas with poor sanitation. But despite causing serious health problems, worms can actually help the immune system of its host as an indirect way of protecting themselves, say authors of the new report.

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For last 100 years, we are groomed to treat non-self as enemy, mother nature as enemy and we are always engaged in unnecessarily war-like responses i.e antibiotics and vaccines.


Research

 

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.

http://www.cell.com/immunity/abstract/S1074-7613(15)00397-0

Highlights

  • The microbiota contributes to helminth-induced modulation of allergic asthma
  • Cecal microbial communities are altered in helminth-infected mice
  • Helminth infection increases microbial-derived short chain fatty acids
  • GPR41 mediates helminth-induced Treg cell suppressor function

Summary

Intestinal helminths are potent regulators of their host’s immune system and can ameliorate inflammatory diseases such as allergic asthma. In the present study we have assessed whether this anti-inflammatory activity was purely intrinsic to helminths, or whether it also involved crosstalk with the local microbiota. We report that chronic infection with the murine helminth Heligmosomoides polygyrus bakeri (Hpb) altered the intestinal habitat, allowing increased short chain fatty acid (SCFA) production. Transfer of the Hpb-modified microbiota alone was sufficient to mediate protection against allergic asthma. The helminth-induced anti-inflammatory cytokine secretion and regulatory T cell suppressor activity that mediated the protection required the G protein-coupled receptor (GPR)-41. A similar alteration in the metabolic potential of intestinal bacterial communities was observed with diverse parasitic and host species, suggesting that this represents an evolutionary conserved mechanism of host-microbe-helminth interactions.

 

Science of Hindu(Sanatana) Social/Community Meal rules

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Science of Social Meal rules
Science of Social Meal rules
30 years back, this was norm across Bharat. You go to anyone’s home, attend any marriage, stay at dharma-shala, meal was always served in a row and food was consumed as Prasad, slowly, gradually and with silence.
 
Serving meal was considered sacred duty. No social status comes into the picture. Everyone serves each other one by one.
 
Sitting in a row for meal is called पंगत or पंक्ति. Everyone sits together and stand up together. This was unwritten custom. Even if you are done with your meal, you sit until everyone completes.
 
If we go 100 years back, there were much stricter rules. For example, you only eat with someone from your वर्ण / जाति / वर्ग / age.
 
And this was considered as discrimination. Right? What a biased and bigoted society India was. These all Hindus! 😀
———————–
Spoiling dharma, all under the shadow of utter ignorance.
 
These rules were never designed to discriminate but to support healthy life. All rituals were designed for मानव कल्याण.
 
Let me give you one example to build the base.
 
“The handshake represents a deeply established social custom. In recent years, however, there has been increasing recognition of the importance of hands as vectors for infection, leading to formal recommendations and policies regarding hand hygiene in hospitals and other health care facilities,”
University of California, Los Angeles is a well-known university and respected name in medical science research. Physicians here suggested to ban handshake in hospitals. They found that despite handwash, handshakes transmit diseases. This is coming from the culture where handshake is deeply ingrained culture. I appreciate scientific temper.
When we handshake, we exchange प्राण. And when the incompatible प्राण is exchanged, we fall sick. We become carrier of sickness (physical and mental).
 
Eating food is highly energy-exchange activity. Lot of different type प्राण is consumed and emitted. When you sit with someone having typical प्राणिक footprint similar to yours, chances of exchanging incompatible प्राण are minimal.
Our results confirm that an occupied space is microbially distinct from an unoccupied one, and demonstrate for the first time that individuals release their own personalized microbial cloud.
 
And since everyone sits together and stand up together, there is a rhythm created, a larger organism, virtual entity, sum total of all compatible प्राणमय शरीर (s). This helps to combat any unforeseen दूषण of food and all प्राणिक impurities associated with it. You see, there was hardly any event of food poisoning. 😉
 
[Hint: Read this paper. We all have unique microbial cloud. https://peerj.com/articles/1258/]
 
This is just a first step to understand eating ritual. Need to spend more time in contemplation for finer conclusion in future. 🙂 (y)
 
Unfortunately, all modern spiritual guru(s) too don’t follow this anymore. Only place I observed this is Kumbh, among SAdhus. 🙂
 
Do not forget, सनातन धर्म is for मानव कल्याण. Keep aside all your rational doubts and act. See the difference. Then we really don’t need all these futile rational analysis. 😉
 
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Supportive Hints
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Humans differ in their personal microbial cloud

https://peerj.com/articles/1258/

Dispersal of microbes between humans and the built environment can occur through direct contact with surfaces or through airborne release; the latter mechanism remains poorly understood. Humans emit upwards of 106biological particles per hour, and have long been known to transmit pathogens to other individuals and to indoor surfaces. However it has not previously been demonstrated that humans emit a detectible microbial cloud into surrounding indoor air, nor whether such clouds are sufficiently differentiated to allow the identification of individual occupants. We used high-throughput sequencing of 16S rRNA genes to characterize the airborne bacterial contribution of a single person sitting in a sanitized custom experimental climate chamber. We compared that to air sampled in an adjacent, identical, unoccupied chamber, as well as to supply and exhaust air sources. Additionally, we assessed microbial communities in settled particles surrounding each occupant, to investigate the potential long-term fate of airborne microbial emissions. Most occupants could be clearly detected by their airborne bacterial emissions, as well as their contribution to settled particles, within 1.5–4 h. Bacterial clouds from the occupants were statistically distinct, allowing the identification of some individual occupants. Our results confirm that an occupied space is microbially distinct from an unoccupied one, and demonstrate for the first time that individuals release their own personalized microbial cloud.

Banning The Handshake From Health Care Settings: Doctors Say Social Custom Spreads Disease Regardless Of Handwashing

http://www.medicaldaily.com/banning-handshake-health-care-settings-doctors-say-social-custom-spreads-disease-regardless-290122

The Western social practice of handshaking has only grown more popular in recent decades with variations up high and down low now often accompanied by the ubiquitous “bro hug.” However, some doctors are pushing to “ban the handshake” in hospitals and doctor’s offices across the country to prevent the spread of communicable disease.

Physicians from the University of California, Los Angeles, argue in an editorial published Thursday in JAMA that handshaking thwarts the practice of handwashing to limit the spread of dangerous pathogens. Soon, health care workers and patients may see the following advisory: “Handshake-free zone: To protect your health and the health of those around you, please refrain from shaking hands while on the premises.”

Although research has long associated handwashing with decreases in bacterial colonization and hospital-acquired infections, only 40 percent of clinicians and other health care workers comply with such mandatory hygiene policies. Among patients and visitors, handwashing hygiene is even lower. And alcohol-based rubs, the most touted solution to hospital hygiene problems, remain ineffective against such dangerous pathogens as Clostridium difficile.

Story of Cordyceps fungi and our food, microbes and GUT

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I often talk about importance of microbes in our physical well-being or in sickness. What I am going to share is very about impact on our mind.

Cordyceps is a fungus. Organism with large work to do for nature than microbes. Photos shared with this posts shows ants infected by this fungi. Once infected by Cordyceps, an ant becomes a zombie. It ignores its usual duties with its colony on the forest floor, and succumbs to the urge to climb a tree. Yes, that is how this fungi can control the ant’s mind. Some 100 cm or more above the forest floor, this ant is forced by fungi to bites down leaf vein and killing self. This is known as the ‘death grip’, as shortly afterwards, the fungus takes the ant’s life. Fungus grows and infect more ants on the forest floor.

The Cordyceps has changed the ant’s behavior, controlling it in an incredibly specific way, to help it give rise to the next generation of fungi.

Example I gave is about fungus but it is not just fungus but microbes, viruses and all living and dead organisms control our behavior. This is because all of them are manifestation of प्राण. Specific combination of प्राण which is programmed to alter your behavior.

Microbes in out Gut also do the same thing. First they take the place. And then control our behavior. You may eat some fast food for taste once but when they microbes loving fast food grows in the GUT, they will force you to eat more and more fast food. That is how food addictions are working in humans. Microbes controlling your habits.

If we understand this, many mental disorders treatment will become easy. Alter the Prana of the environment and see the magic. Same goes with Autistic children.

Only way to control Prana is Mind. मनोमय कोष had higher control over disturb or polluted प्राणमय कोष. But our mind is engaged in worldly pleasures and addictions. TV, News, Gossips, stress of daily life makes mind dull. Pollution by burning fossil fuels, cutting forest, cement cities reduces our pranic intelligence. In short, we all slowly become zombies like the ant becomes after fungus infection. Easy to control like slaves.

Ant has no choice but to succumb to fungus control due to limited mind but we have unlimited mind. Use it.

What you eat is important. Where you eat is equally important. How you eat is too. Eat = Physical food, mental food. Where you live is important. How clean you keep your home is also important. Ultimately how good you are at controlling प्राणिक & मानसिक exchange with environment will decide well-being of your life.

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