Microbes

Microbes

Gut is not Gutter : Your gut bacteria don’t like junk food – even if you do

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Do you like to visit dirty and untidy homes? Do you give the same treatment to your relatives and friends when they visit your home? Do we scold them for coming at wrong time?

GUT is home for billions of bacteria. They stay their to do numerous biological tasks for our well-being. In fact, their population variety decides, what nutrients we can digest and what not. Their population really drives our emotional responses. Richness in their variety is essential.

We rely on our bacteria to produce much of our essential nutrients and vitamins while they rely on us eating plants and fruits to provide them with energy and to produce healthy chemicals which keep our immune system working normally.

We are unlikely to stop people eating fast food, but the devastating effects on our microbes and our long term health could possibly be mitigated if we also eat foods which our microbes love like probiotics (yogurts), root vegetables, nuts, olives and high-fibre foods. What they seem to crave, above all else, is food diversity and a slice of gherkin in the burger just isn’t enough.

When we keep eating junk food, we kill them. We show them the door.

Tim Spector, Professor of Genetic Epidemiology at King’s College London, did an experiment with his own son.

Read to know how junk food destroys GUT population.


Research


Your gut bacteria don’t like junk food – even if you do

https://theconversation.com/your-gut-bacteria-dont-like-junk-food-even-if-you-do-41564

“Tom’s gut had seen massive shifts in his common microbe groups for reasons that are still unclear. Firmicutes were replaced with Bacteroidetes as the dominant type, while friendly bifidobacteria that suppress inflammation halved. However the clearest marker of an unhealthy gut is losing species diversity and after just a few days Tom had lost an estimated 1,400 species – nearly 40% of his total. The changes persisted and even two weeks after the diet his microbes had not recovered. Loss of diversity is a universal signal of ill health in the guts of obese and diabetic people and triggers a range of immunity problems in lab mice.”

Microbes, Vastu and Pro-कल्याण Architecture

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Vastu

Back to back good news from science field. (First it was micro wind turbine governed by microbes)

I wrote last year here how and why वास्तु विद्या in its truest form is need of the hour. I also wrote how home microbes influence our day to day life. And why home-made dahi and chaas are better than factory made.

Here, one more research, urging architects to take care of home microbes while designing homes.

Recall, my yesterday’s post ({आवह, प्रवह,संवह ,उद्वह,विवह,परिवह,परावह} * {ब्रह्मलोक , इन्द्रलोक ,अंतरिक्ष , भूलोक की पूर्व दिशा , भूलोक की पश्चिम दिशा , भूलोक की उत्तर दिशा और भूलोक की दक्षिण दिशा} = 49 मरुतs , life forces, air movements, governing life. Bow to मरुतs , bow to their democratic existence in groups!)

So in this context, if Vastu suggest no entry from south-west, it is No! If East is favorable, it is! If Kitchen is needed in Agni , it is needed! We live so shallow life that we hardly realize the subtle impact.

Now, when western architects will explain, we will welcome it 😉

Check old posts on same subjects in comments.


Research


Buildings, Beneficial Microbes, and Health

http://www.cell.com/trends/microbiology/abstract/S0966-842X(16)30021-X?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0966842X1630021X%3Fshowall%3Dtrue

Read on:

Architectural design is often concerned with energy efficiency or aesthetics, not microbial exposure. But, in a Science & Society article published July 7 in Trends in Microbiology, Yale environmental engineers make a case for assessing the benefits of having these unseen organisms in our homes. Maybe, they say, instead of pushing all of them out, we should let the right ones in.

“It’s a common misconception that all microbes found in one’s home are hazardous to your health,” says Yale Professor of Chemical and Environmental Engineering Jordan Peccia (@jordan_peccia), co-author of the review with PhD student Sarah Kwan. “Many have no impact on health, while some may even be beneficial.”

Past studies have shown that children growing up on a farm (or even in a home close to a rural area), are exposed to such beneficial microbes, and are less likely to develop allergies as a result. In one example, children from a Bavarian family (a population known for their agrarian lifestyle, such as working the fields, using horses for transport, and drinking unpasteurized milk) had less than half the levels of asthma compared to a suburban European family (5.2% versus 19.1%). This effect was found to persist into adulthood. This is likely because some microbes in the body send signals to white blood cells known as T cells to form T regulatory cells, which prevent unnecessary immune responses.

“One big question becomes how building design (e.g., the geographical layout, the building materials, occupancy, and ventilation) modulates microbial exposure, and our own microbiomes,” says Peccia. “As more and more beneficial microbes are identified, we–architects, engineers, and the general public–need to think about how we can facilitate our exposure to them.”

“There are certainly trade-offs we need to better understand and circumvent,” he adds. “Indoor air quality is often worse than outdoor air quality, so building ventilation with outdoor air makes a lot of sense. However, in cities with very poor outdoor air quality, increased ventilation results may result in unhealthy exposures to outdoor air contaminants.”

Short of working on a farm, one way we can “train” our immune system is through exposure to animals, especially cats and dogs. Aside from carrying their own families of microbes, they also can track in common bacteria and fungi from the outdoors, further contributing to the aforementioned “beneficial diversity” of indoor microbes. These can then be easily inhaled or swallowed when trapped in a tightly enclosed space, such as a home or office building, where we inhale gallons of air each day and sometimes ingest floor dust.

Although this field is still in its infancy, Peccia does have some advice for building occupants, namely, that there is not a “one size fits all” approach to improving the microbiome in one’s home. “Not everyone should run out and get a dog, of course,” he says, “but we can work to develop new, quantitative approaches for solving these problems–something better than our portable air filters and inhalers.”

Image credit: CREDIT
Peccia and Kwan/Trends in Microbiology 2016

Art of Surfing in Microbial Sea: Balance

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Infectious means easily spread. Many sicknesses are called Infectious. And we blame bacteria and viruses for it! 😉 🙂

Balance is the key
Balance is the key

In reality, you will be afflicted only when your body is not in balanced state. Read this view.

Skimboarding or Surfboarding is an interesting board-sports for those who live near sea.

Board is used to glide across the water’s surface to meet an incoming, breaking wave, and ride it back to shore. Never done it but must be thrilling and mind bending. To balance the self, we have only one alternative, to balance self as per pattern of the wave. We can not control the wave.

Our environment is ocean of bacteria and viruses. Mother nature does not like vaccum. Place your hand anywhere and you will be in contact with millions and billions bacteria and viruses. Infection is a vacuum filling activity by mother nature. Like a giant wave to face when you are doing Skimboarding. You cannot anyway kill all the bacteria like you cannot change the pattern of the wave. One wave will go and another will come (Modern medicine calls it resistant bacteria 🙂 ). Similarly, antibiotics will wipe out one set of microbes and another will take the place.

Like a Skimboarders @ sea, we must learn to balance self in this sea of bacteria. That is the essence of immunity. Killing bacteria is short-sighted solution. Those who cannot envision ocean can only try to control and bend wave. 🙂 My two years old son do it often 😉

Think about it. (Y)

Soil Health Card is useless without गौ आधारित खेती (Cow-based farming)

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SoilMicrobesCarbon

American university proclaims:

“With more than 7 billion microorganisms in the soil, it’s no surprise we still have a lot to learn about them and their impact on the environment. “Consequently, the activity of microorganisms in soil has the potential to alleviate or worsen climate change, so we need to form predictions regarding their activities.”

Do you think without Gau mata, one can achieve this?

Remember, I often share here that

Gau out = Desert In
Desert In = Desert Religion In (Islam/Christianity)

Soil health card may be good way to track soil nutrients but it is useless if you cannot understand value of cow in maintaining soil health. Soil health does not only mean NPK! Or Organic matter. It mean Prana! and only Gau mata can provide Prana!!

Not only carbon cycle, Gau mata has potential to stabilize all natural cycles!! She is medium via which we should embrace primordial prana i.e. Sun


Research


WVU researcher uncovers influence of microorganisms on soil carbon storage

With more than 7 billion microorganisms in the soil, it’s no surprise we still have a lot to learn about them and their impact on the environment. A West Virginia University researcher is uncovering critical information about these tiny organisms under our feet, which although small, can have a huge impact on the environment.

Ember Morrissey, assistant professor of environmental microbiology in the Davis College of Agriculture, Natural Resources and Design, received a $150,000 grant from National Science Foundation’s Division of Environmental Biology’s Early-concept Grants for Exploratory Research program, known as EAGER, to increase understanding of the behavior of microorganisms in the soil to provide descriptions of microbial function that currently aren’t available.

Morrissey’s research will lay the groundwork needed to figure out how soil can be managed to address environment-related processes and issues, including global warming and climate change.

Of particular interest for Morrissey and other researchers is the ability to formulate more precise predictions of microorganisms’ carbon cycling, or how they use and create carbon, a key to combatting climate change.

“Soil stores a large fraction of the earth’s carbon – actually more carbon than the atmosphere and biosphere combined,” Morrissey explained. “Microorganisms break down and consume this carbon as they live and grow, converting it into the greenhouse gas carbon dioxide.

“Consequently, the activity of microorganisms in soil has the potential to alleviate or worsen climate change, so we need to form predictions regarding their activities.”

https://wvutoday.wvu.edu/stories/2017/01/17/wvu-researcher-uncovers-influence-of-microorganisms-on-soil-carbon-storage

 

Local Food, Mother’s diet and Infant’s milk microbes

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Local Food
Even closed door medical conferences across India cherish importance of local diet influence, society follow market and media and enjoy global diet. One of the fundamental error in selection of food is to select food for taste and urge to taste non-local food.
 
For example: It is perfectly ok to eat Idli-Sambhar in Kerala but having same every day in Gujarati home living in Gujarat?
 
It is perfectly ok to eat apple in Himachal but having same in hot and humid Gujarat summer?
My common sense suggest to prefer only local diet over non-local taste-lust food selection.
 
For would-be mothers, it is important to maintain local diet if they wish their breast-feeding. What you eat, decides GUT microbes and in turn pass on legacy to newborn babies via breast-milk!
Your local diet is the immunity for your kid. During and after breast-feeding. And not the packaged processed food!
Educate mothers around you and help building strong Nation via strong future geneations.
Here is the interesting study looking to localization of GUT microbes of breast-feeding mothers’ GUT. It supports the hypothesis that there is no alternative of local diet. All healthy diet fads are marketing gimmick or at best, suitable to local population where the diet is showing results. What is good for pregnant mother in China, may not work for same in India!
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Research
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Bacterial Composition and Diversity in Breast Milk Samples from Mothers Living in Taiwan and Mainland China

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447776/

Human breast milk is widely recognized as the best source of nutrients for healthy growth and development of infants; it contains a diverse microbiota. Here, we characterized the diversity of the microbiota in the breast milk of East Asian women and assessed whether delivery mode influenced the microbiota in the milk of healthy breast-feeding mothers. We profiled the microbiota in breast milk samples collected from 133 healthy mothers in Taiwan and in six regions of mainland China (Central, East, North, Northeast, South, and Southwest China) by using 16S rRNA pyrosequencing. Lactation stage (months postpartum when the milk sample was collected) and maternal body mass index did not influence the breast milk microbiota. Bacterial composition at the family level differed significantly among samples from the seven geographical regions. The five most predominant bacterial families were Streptococcaceae(mean relative abundance: 24.4%), Pseudomonadaceae (14.0%), Staphylococcaceae (12.2%), Lactobacillaceae (6.2%), and Oxalobacteraceae (4.8%). The microbial profiles were classified into three clusters, driven by Staphylococcaceae (abundance in Cluster 1: 42.1%), Streptococcaceae (Cluster 2: 48.5%), or Pseudomonadaceae (Cluster 3: 26.5%). Microbial network analysis at the genus level revealed that the abundances of the Gram-positive StaphylococcusStreptococcus, and Rothia were negatively correlated with those of the Gram-negative AcinetobacterBacteroidesHalomonasHerbaspirillum, and Pseudomonas. Milk from mothers who had undergone Caesarian section (C-section group) had a significantly higher abundance of Lactobacillus (P < 0.05) and a higher number of unique unclassified operational taxonomic units (OTUs) (P < 0.001) than that from mothers who had undergone vaginal delivery (vaginal group). These findings revealed that (i) geographic differences in the microbial profiles were found in breast milk from mothers living in Taiwan and mainland China, (ii) the predominant bacterial families StreptococcaceaeStaphylococcaceae, and Pseudomonadaceae were key components for forming three respective clusters, and (iii) a significantly greater number of unique OTUs was found in the breast milk from mothers who had undergone C-section than from those who had delivered vaginally.

Distinct Patterns in Human Milk Microbiota and Fatty Acid Profiles Across Specific Geographic Locations.

https://www.ncbi.nlm.nih.gov/pubmed/27790209

Conclusion

https://www.frontiersin.org/files/Articles/217349/fmicb-07-01619-HTML/image_m/fmicb-07-01619-g002.jpg
https://www.frontiersin.org/files/Articles/217349/fmicb-07-01619-HTML/image_m/fmicb-07-01619-g002.jpg

Our results demonstrate differences in the composition of lipids and microbiota in breast milk in different geographic regions and offer a new insight to the differences in development of gut microbiota in infants in different geographic areas. The impact of mode of delivery on milk microbiota composition appears to be even more important within all geographical regions. Furthermore, our study shows distinct association between fatty acid composition and individual microbiota in breast milk, suggesting important role of lipids in shaping the microbial profile which likely one important factor influencing the infant gut microbiota development.

Type 1 Diabetes, Microbes and Ganapati

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Bacteria diabetes

The part of the alimentary canal between the stomach and the anus is known as GUT. This is reservoir of microbes. Critical digestive processes happen here.

In Ayurveda, this place is considered as मूलाधार चक्र.गणपति resides here. Ayurveda considers body beyond physical body and energy layer is one of such layer, प्राणमय कोष. Energy @ मूलाधार चक्र is responsible for person’s intelligence, valor and many other traits. And Ganapati resides here. He controls all activities.

Tvam muladhara sthitosi nityam |
त्वं मूलाधार स्थितोऽसि नित्यं।
Lord Ganesha! You always dwell in muladhara chakra!

मूलाधार : शक्ति Center near Gut & anus : Abode of मरुत गण (Microbes) and their leader गणपति

He is the lord of muladhara chakra. In other words, he rules our microbial flora (मरुत गण) and make sure only body-friendly मरुत गण resides in the abode.

मरुत गण (Microbes) : गण पति (Ganesha) : गण (Citizens) & पति (Protector) live together @ Muladhara

Awakening गण पति शक्ति is critical for maintaining health (which is critical for self-realization). Only he can protect and act as gatekeeper of Muladhara (Gut) so that body is kept protected from pathogens & aasuri shakti.

Now, let us come to diabetes!

Type 1 diabetes (T1D) is an autoimmune disease in which a person’s pancreas stops producing insulin, a hormone that enables people to get energy from food. It occurs when the body’s immune system attacks and destroys the insulin-producing cells in the pancreas, called beta cells. While its causes are not yet entirely understood, scientists believe that both genetic factors and environmental triggers are involved. Its onset has nothing to do with diet or lifestyle. There is nothing you can do to prevent T1D, and—at present—nothing you can do to get rid of it.

Statistics

  • 1.25M Americans are living with T1D including about 200,000 youth (less than 20 years old) and over a million adults (20 years old and older)1,2,5
  • 40,000 people are diagnosed each year in the U.S.1, 2
  • 5 million people in the U.S. are expected to have T1D by 2050, including nearly 600,000 youth.2,3
  • Between 2001 and 2009 there was a 21% increase in the prevalence of T1D in people under age 20.3
  • $14B T1D-associated annual healthcare costs in the U.S.
  • Less than one-third of people with T1D in the U.S. are achieving target blood glucose control levels6
  • T1D is associated with an estimated loss of life-expectancy of up to 13 years7

As per latest research, microbes is the cure!!


Bacteria that Prevents Type 1 Diabetes

http://presse.inserm.fr/en/bacteria-that-prevents-type-1-diabetes/20118/


A pancreatic islet of Langerhans expressing the immunoregulator antimicrobial peptide CRAM (in red). The insulin-producting beta-cells are in green and the glucagon-producting alpha-cells are in blue. © Julien Diana
A pancreatic islet of Langerhans expressing the immunoregulator antimicrobial peptide CRAM (in red). The insulin-producting beta-cells are in green and the glucagon-producting alpha-cells are in blue. © Julien Diana

 

To combat pathogens, the immune system has developed various mechanisms to detect, defend against and even destroy micro-organisms that are harmful to the body. This includes antimicrobial peptides and natural proteins that destroy pathogenic bacteria by disrupting their cellular membrane. Not only are they produced by immune cells, they are also produced by cells whose functions are not immune-related.

A research team coordinated by Julien Diana, an Inserm Research Fellow at Inserm Unit 1151 “Institut Necker-Enfant Malades” [Necker Institute for Sick Children] (Inserm/CNRS/Université Paris Descartes), is focussing on a category of antimicrobial peptides, i.e.cathelicidins. Apart from their protective function, these peptides have also exhibited immunoregulatory abilities against several autoimmune diseases. As such, scientists hypothesise that cathelicidins may be involved in the control of type 1 diabetes, an autoimmune disease where certain cells in the immune system attack beta cells in the pancreas which secrete insulin.

Firstly, they observed that beta pancreatic cells in non-diseased mice produce cathelicidins and that, interestingly, this production is impaired in diabetic mice.

To test this hypothesis, they are injecting diabetic mice with cathelicidins where production is defective.

“Injecting cathelicidins inhibits the development of pancreatic inflammation and, as such, suppresses the development of autoimmune disease in these mice” states Julien Diana.

Microbes or Bacteria as popularly known, are our best friends. They save us from Type 1 diabetes! 🙂
 
But we will keep blind eyes towards these facts and apply antibiotics! create situations where antibiotics become unavoidable! 🙁
 
From Asthma to cancer to diabetes to irregular bowels to allergies to intellect to memory – we are at microbes’ mercy!
 
And who is there leader? गणपति! Worship him!! It is great psychological treatment (I know, this is very lowly reason for worship 🙂 )! After all, majority treatments are placebo! 🙂 

Maa Lakshmi and Microbial Wealth

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p01lb5zc835aead88738164c8c5188111d904820--maa-chakras

Real wealthy human carries rich microbial colonies in his Gut (The part of the alimentary canal between the stomach and the anus).

Rich in variety of healthy bacteria in Gut, healthier life, healthy brain -> healthy mind -> affirmative actions.

Health is wealth. 🙂

What do we do? We kill carriers of Maa Lakshmi at our door step.

How?

Smoking, alcohol, drugs, antibiotics.

Toxic Mouthwash, Microbes, Nitric Oxide and Blood Pressure

 

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Solution for foul mouth smell is not mouthwash but healthy eating habit. Foul smell is an early sign of faulty GI track (digestive track).

But since we consider ourselves citizens of scientific age, and we trust TV ads as equal to science experiments, trusting superficial perception more over age-old practices, we use mouthwash
😀
.

And what do we get in return?

We kill part of ourselves. We kill bacteria in mouth who help us in reducing nitrate metabolites from food into NO (nitric oxide). NO (nitric oxide) plays important role in maintaining blood vessel wall pressures. It keeps the blood pressure optimum. So far medical science was ignorant of this usage of NO. In the past 5 years, nitric oxide (NO) has become recognized as a major player in most physiological and pathophysiological processes. Not only blood pressure maintenance, NO plays important role in brain processes.

So when we kill bacteria in mouth, we kill one of the sources of NO (nitric oxide). This results in high blood pressure and related anomalies.

What is the solution?

1) Use natural mouth freshener if needed i.e. Paan without tobacco. Only after heavy meals. Not daily.
2) Do dant manjan (teeth cleaning) using powder prepared from cow dung ash. It is full of nitrogen metabolites i.e. food for bacteria which ultimately results in NO that keep blood pressure normal.
3) Mix sesame oil with dant manjan and use this paste to do gentle massage too teeth roots. Gargle sesame oil.
4) Gau milk, ghee, urine, gobar, chemical free jaggery, honey procured ethically from jungle – these all are rich sources of good bacteria and their food. When you include them in food, body always remain in healthy state.

Reference material:

Water Pipes, Microbes and Prana

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capture

 

This helps my hypothesis that there are actually no bad bacteria 🙂 There are manifestation of प्राण, doing their job. Their duties as per their धर्म.
 
If you are living selfish and अधार्मिक life, their duties may look like bad for you.
 
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Researchers from Lund University in Sweden have discovered that our drinking water is to a large extent purified by millions of “good bacteria” found in water pipes and purification plants.
 
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This is the reason, our culture teaches to drink water from different sources (Well/River/Pond) in different seasons so that different forms of प्राण bless the water.प्राण
 
This is the reason, Ashtang Hrudayam prescribes water pot in home should have access to sunlight and wind.प्राण
This is the reason why we do pure desi cow ghee’s diya near water-place in the kitchen.प्राण
 
This is the reason why Vastu Shashtra prescribes kitchen and well in specific direction.प्राण
 
This is the reason why we grow specific grass near water bodies.प्राण
 
This is the reason we worship grass like durva. प्राण
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Bacteria in pipes to ghee lamp – One thing common : प्राण
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https://www.youtube.com/watch?v=XNMDHaZJVLo
11553710-a-broken-pipe-that-leaks-water-in-all-directions-stock-photo-plumbing

Our water pipes crawl with millions of bacteria

Researchers from Lund University in Sweden have discovered that our drinking water is to a large extent purified by millions of “good bacteria” found in water pipes and purification plants. So far, the knowledge about them has been practically non-existent, but this new research is about to change that.

 

 
http://www.lunduniversity.lu.se/article/our-water-pipes-crawl-with-millions-of-bacteria

 

Pathogenicity (Ability to cause diseases) is not a rule

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We are brainwashed to believe that diseases are natural and they happen due to microbes and viruses.

In my several notes, I tried to represent alternate perspective.

Here is what Biologist Lewis Thomas said in 1974.

In real life, however, even in our worst circumstances we have always been a relatively minor interest of the vast microbial world. Pathogenicity is not the rule. Indeed, it occurs so infrequently and involves such a relatively small number of species, considering the huge population of bacteria on the earth, that it has a freakish aspect. Disease usually results from inconclusive negotiations for symbiosis, an overstepping of the line by one side or the other, a biologic misinterpretation of  borders.

So? Stop blaming microbes for all your failed communications with them! Instead of blaming them, cultivate your immunity! Learn to live in मुनि state! (More here about Muni and Immunity )

Some bacteria are only harmful to us when they make exotoxins, and they only do this when they are, in a sense, diseased themselves. The toxins of diphtheria bacilli and streptococci are produced when the organisms have been infected by bacteriophage; it is the virus that provides the code for toxin. Uninfected bacteria are uninformed. When we catch diphtheria it is a virus infection, but not of us. Our involvement is not that of an adversary in a straightforward game, but more like blundering into someone else’s accident.

Some claims it is diphtheria vaccine that has saved the children! I say, it is post-world war, improved environment that had reduced the cases of diphtheria. Environmental stress reduced, diphtheria not affected by stress-messengers i.e. viruses (bacteriophage) and hence no exotoxins so no diphtheria led deaths.

grafic-1-17_660_486

Lewis Thomas further writes:

I can think of a few microorganisms, possibly the tubercle bacillus, thesyphilis spirochete, the malarial parasite, and a few others, that have a selective advantage in their ability to infect human beings, but there is nothing to be gained, in an evolutionary sense, by the capacity to cause illness or death. Pathogenicity may be something of a disadvantage for most microbes, carrying lethal risks more frightening to them than to us. The man who catches a meningococcus is in considerably less danger for his life, even without chemotherapy, than meningococci with the bad luck to catch a man. Most meningococci have the sense to stay out on the surface, in the rhinopharynx. During epidemics this is where they are to be found in the majority of the host population, and it generally goes well. It is only in the unaccountable minority, the “cases,” that the line is crossed, and then there is the devil to pay on both sides, but most of allfor the meningococci.

Think about it. We need radical new perspective about life. Then only we can see destruction of environment going around. If we don’t nurture environment, we will soon invite another series of epidemic like we did in 18th, 19th and 20th centuries. And no technology would save us!

 

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