Health

Health

Free Checkup Camp Trap

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I see many corporate hospitals arranging free check up camps. Not all of them are fake but there are certainly motives to convert attendees of the camps into future patients.

Do not rely on one source of diagnosis blindly. Do take second opinion.

PS: This post is not to call every doctor as fraud. This is to make people aware that not all doctors are saint either. Be alert. (Y)

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More Doctors Confessing To Intentionally Diagnosing Healthy People With Cancer To Make Money

It happens more often than you can imagine, but more Doctors are finally getting caught in the act of misrepresenting their oath and fraudulently diagnosing healthy patients with cancer to turn a quick buck from kickbacks on chemotherapy poisons.

Why shouldn’t Doctors lie when the entire cancer industry is one gigantic fabrication from start to finish? Is it any wonder that cancer societies worldwide put a far greater financial initiative on chemotherapy and radiation research than disease prevention techniques? Preventing disease doesn’t make money, but treating disease certainly does.

Take Dr. Farid Fata, a prominent cancer doctor in Michigan who admitted in court one year ago to intentionally and wrongfully diagnosing healthy people with cancer. Fata also admitted to giving them chemotherapy drugs for the purpose of making a profit.

Read more : http://preventdisease.com/news/15/010715_Doctors-Confessing-To-Intentionally-Diagnosing-Healthy-People-With-Cancer.shtml

https://www.justice.gov/usao-edmi/us-v-farid-fata-court-docket-13-cr-20600

 

 

The human milk microbiota

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So far, we were told that Mother’s milk is sterile. Absolutely pure.
And with this image, we also strive for Dairy milk. Pasteurized! Sterile. No bacteria at all!

That is the level of modern scientific temper we are proud of. 🙂 And investing heavily so that our kids are groomed under it. 🙂 (This does not mean I do not respect science and her achievements. Just a direction and outlook to look at nature is wrong).

In Ayurvedic understanding, no organism is harmful. Everyone is doing their job (or following their Dharma). Bacteria in milk are necessary. They are their to help the consumer of the milk.

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“Culture-dependent and -independent techniques have revealed the dominance of staphylococci, streptococci, lactic acid bacteria and bifidobacteria in this biological fluid, and their role on the colonization of the infant gut. These bacteria could protect the infant against infections and contribute to the maturation of the immune system, among other functions.”

It is high time we get rid of this germ-phobia. ASAP. Sooner the better.

The way mother’s milk helps infant, Gau milk helps adults.

On immediate basis, dairy milk should be replaced with raw milk from Gau shala where ethical practices are followed (Calf’s milk is not snatched. No hormone injections are used. Machines are not used for milking etc)


Research


The human milk microbiota: origin and potential roles in health and disease.

https://www.ncbi.nlm.nih.gov/pubmed/22974824

Human milk has been traditionally considered sterile; however, recent studies have shown that it represents a continuous supply of commensal, mutualistic and/or potentially probiotic bacteria to the infant gut. Culture-dependent and -independent techniques have revealed the dominance of staphylococci, streptococci, lactic acid bacteria and bifidobacteria in this biological fluid, and their role on the colonization of the infant gut. These bacteria could protect the infant against infections and contribute to the maturation of the immune system, among other functions. Different studies suggest that some bacteria present in the maternal gut could reach the mammary gland during late pregnancy and lactation through a mechanism involving gut monocytes. Thus, modulation of maternal gut microbiota during pregnancy and lactation could have a direct effect on infant health. On the other hand, mammary dysbiosis may lead to mastitis, a condition that represents the first medical cause for undesired weaning. Selected strains isolated from breast milk can be good candidates for use as probiotics. In this review, their potential uses for the treatment of mastitis and to inhibit mother-to-infant transfer of HIV are discussed.

Midnight Munches to Irregular Meals : Memory Disorders to Cancer

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5 years back, one young basketball player from local university died on the spot while doing his daily practice.

Many young players I meet, are not fit for long physical workout.

All of them have one thing common:

“Work hard, party harder. Addictions. Late night parties. Early morning eating after long talks. Tea after sports. Tea before sports. Late night movies with popcorns.”

Most of university students are zombies and mediocre.

One of many root causes is food habit. Timely regular meals is ignored. Eating anywhere, anytime is the fashion.

For married couple, after marriage, you will start observing indigestion issues in 1 or 2 years. Many of them even suffer from chronic issues like ulcers, IBS and cancer.

Reason? Observe following daily routine.

deadlyschedule

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Sex after Meal. Exercise after sex. Bath after exercise. What a foolish way to spend life!! As per Ayurveda, at least 4 hrs between meal and sleep. At least 1 hr between exercise and bath. No exercise before and after sex!! When this is not followed, we stress double duty on Apana  Prana vayu. Since life-procreation is higher priority task, Apana for digestion is compromised and leads to indigestion. Indigestion is root cause of 99% sicknesses.

“Robust sleep/wake rhythms are important for health and cognitive function. Unfortunately, many people are living in an environment where their circadian system is challenged by inappropriate meal- or work-times.”

“An occasional late-night raid on turkey leftovers might be harmless but new research with mice suggests that making a habit of it could alter brain physiology.

Eating at times normally reserved for sleep causes a deficiency in the type of learning and memory controlled by the hippocampal area of the brain, according to findings in the journal eLife.”

———

Once the life rhythms are disturbed, cascading impact is unforeseen. Not only memory as this paper suggests, fatal consequence.


Research


An occasional late-night raid on turkey leftovers might be harmless but new research with mice suggests that making a habit of it could alter brain physiology.

Eating at times normally reserved for sleep causes a deficiency in the type of learning and memory controlled by the hippocampal area of the brain, according to findings in the journal eLife.

Researchers from the Semel Institute in the David Geffen School of Medicine at University of California, Los Angeles (UCLA) became interested in the cognitive effects of eating at inappropriate hours because it is already known to have an impact on metabolic health, for example leading to a pre-diabetic state.

“We have provided the first evidence that taking regular meals at the wrong time of day has far-reaching effects for learning and memory,” says first author Dawn Loh from the UCLA Laboratory of Circadian and Sleep Medicine.

Misaligned feeding impairs memories

Robust sleep/wake rhythms are important for health and cognitive function. Unfortunately, many people are living in an environment where their circadian system is challenged by inappropriate meal- or work-times. Here we scheduled food access to the sleep time and examined the impact on learning and memory in mice. Under these conditions, we demonstrate that the molecular clock in the master pacemaker, the suprachiasmatic nucleus (SCN), is unaltered while the molecular clock in the hippocampus is synchronized by the timing of food availability. This chronic circadian misalignment causes reduced hippocampal long term potentiation and total CREB expression. Importantly this mis-timed feeding resulted in dramatic deficits in hippocampal-dependent learning and memory. Our findings suggest that the timing of meals have far-reaching effects on hippocampal physiology and learned behaviour.

https://elifesciences.org/content/4/e09460%20

Toxic Mouthwash, Microbes, Nitric Oxide and Blood Pressure

 

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Solution for foul mouth smell is not mouthwash but healthy eating habit. Foul smell is an early sign of faulty GI track (digestive track).

But since we consider ourselves citizens of scientific age, and we trust TV ads as equal to science experiments, trusting superficial perception more over age-old practices, we use mouthwash
😀
.

And what do we get in return?

We kill part of ourselves. We kill bacteria in mouth who help us in reducing nitrate metabolites from food into NO (nitric oxide). NO (nitric oxide) plays important role in maintaining blood vessel wall pressures. It keeps the blood pressure optimum. So far medical science was ignorant of this usage of NO. In the past 5 years, nitric oxide (NO) has become recognized as a major player in most physiological and pathophysiological processes. Not only blood pressure maintenance, NO plays important role in brain processes.

So when we kill bacteria in mouth, we kill one of the sources of NO (nitric oxide). This results in high blood pressure and related anomalies.

What is the solution?

1) Use natural mouth freshener if needed i.e. Paan without tobacco. Only after heavy meals. Not daily.
2) Do dant manjan (teeth cleaning) using powder prepared from cow dung ash. It is full of nitrogen metabolites i.e. food for bacteria which ultimately results in NO that keep blood pressure normal.
3) Mix sesame oil with dant manjan and use this paste to do gentle massage too teeth roots. Gargle sesame oil.
4) Gau milk, ghee, urine, gobar, chemical free jaggery, honey procured ethically from jungle – these all are rich sources of good bacteria and their food. When you include them in food, body always remain in healthy state.

Reference material:

Poisoned Inheritance

Everyone talks about pregnant mother’s diet but no one really twist ear of would-be father and demand right diet from him.

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No married couple is sincere enough for it.

Result? Poisoned inheritance. Not mere genes! But the environmental ghost (epigenetical factors).

A lack of folate in the diet of male mice reprograms their sperm in ways that damage their offspring. Could the same be true in men?

While female is deemed pregnant after conception, male partner remains pregnant for 9 months before conception (sperms become mature in 72 days. Before it, some period is needed for cleansing of the would-be father’s body).

So if you are planning for child, start focusing on right diet for at least 9 months before you meet your partner for child.

Pregnancy begins from the thought of having child to delivery of the child. At least 18 months. 9 months for male partner’s preparation and 9 months of mother’s nurturing.

Take care!


Research


http://www.economist.com/news/science-and-technology/21591547-lack-folate-diet-male-mice-reprograms-their-sperm-ways?fsrc=nlw%7Chig%7C12-12-2013%7C7186683%7C35321167%7CAP

A lack of folate in the diet of male mice reprograms their sperm in ways that damage their offspring. Could the same be true in men?

DOCTORS recommend that women who are pregnant, or plan to be, eat plenty of green, leafy vegetables. These are a source of vitamin B9—or folate, as it is also known—a substance that helps embryos develop by encouraging the formation of the neural tube, the precursor to the brain and the spinal cord. Folate has never been recommend to putative fathers, though, for the obvious reason that, sperm apart, a father contributes nothing to the physical substance of an embryo.

If the results of research on mice, by Sarah Kimmins and her colleagues at McGill University, in Montreal, are found to apply to people too, that may need to change. For, as they report in Nature Communications, they have discovered something odd: that folate deficiency in fathers can, in rodents at least, be as debilitating for embryos as deficiency in mothers. An absence of folate when sperm are forming causes alterations in them that affect the mice which grow from the eggs those sperm fertilise. In particular, Dr Kimmins saw serious deformities of head, spine and limbs.

This damage seems to be caused by epigenetic modification, the subject of a rapidly emerging field of research. Such modification involves a process called methylation, which alters the behaviour of genes in a way that can be passed from one generation to another. Folate’s job is to regulate methylation. How epigenetic modification might cause the defects Dr Kimmins saw, she does not yet know. But when she and her team looked at changes in the methylation patterns of genes in the sperm of folate-deficient rats they found things there that might cause other phenomena, which are not apparent at birth. These include cancer, diabetes, and even autism and schizophrenia.

Mind : Root of many health issues

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As per experience of my best doctor friend, roots of many sicknesses are in mental stress or environmental stress or both. Reduce it and you will be healed.

First thing he asks patient on examination is not about physical symptoms but environmental conditions, mental conditions. There he finds maximum root causes.

Health is प्रकृति, your inborn self. Sickness is विकृति, derangement from your प्रकृति (Your inborn bodily and mental constitution). True treatment fix the derangement scale of प्रकृति. Pseudo medicine tries to hide symptoms of विकृति for time being which gives you false ego of being healthy.

Prkriti
Prkriti

Most diseases, except those natural to the course of time (part of development/growth of child i.e. Viral infection or part of aging i.e. pain in joints), are from the psychological imbalance born of unnecessary self-consciousness/Ego/Anger/Greed i.e. mental stress (Positive or negative stress*).

So solution lies in curing all layers of body and not just the physical layer i.e.

Modern medicine with only physical mass can at the best cure first layer of body i.e. Physical body.

Homeopathy medicine with Pranic layer (Due to continuous churning process during preparation) can best cure second layer of body along with little impact on physical layer. So if your sickness is rooted in Pranic body, you will be cured. Otherwise, you will find it pseudo science.

Ayurvedic medicines can cure both physical and Pranic layer due to their liveliness.

But if the sickness is rooted in mental plane, no physical medicine can cure it. To cure the mental body, you need good thoughts. You need good company (friends and family who are always positive about life and you). You need healthy talks. You need to spend more time with mother nature. Your doctor ( Be it allopathic or homeppathic or Ayurvedic) should be pious (and not greedy businessman planning to grab insurance money) and has selfless intention to see you in good health. You need to remain positive in all odd situations presented by life.

Think about it. Nothing wrong in keeping our ‘Educated-in-Science Ego ‘ aside if this understanding bears good health and keep us healthy forever. Take care.

* Positive stress – uncontrolled desire to remain ahead in rat race, chasing material things and for that the sacrifice of other aspects of life (Family, friend, children etc).
* Negative stress – Anger/Greed/Lust

Gut as Second Brain: End of Medical Science Dark Age

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I consider present Gene-centric science as dark age of medical science.

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For centuries of dark age modern science, they were saying, it is head that control our life. Recently, in last 20 years, they have started accepting heart’s nervous control as critical player. And now, Embedded in the wall of the gut, the enteric nervous system (ENS) has long been known to control digestion. Now it seems it also plays an important role in our physical and mental well-being.

Tomorrow, it will be appendix. Day after tomorrow, hands and legs nervous response.

We need to understand, sooner or later, that it is MIND and not the BRAIN! Brain is mere an instrumental agent, catering our subtle bodies (Refer पञ्चकोष शरीर)

Read this to realize importance of gut.
With our limited knowledge: Healthy GUT -> Healthy gateway in form of nervous responses for mind to carry out actions

By the way, how do we urbanites eat? Lol. Look into mirror…you will see yourself devastating sacred eating ritual. TV, radio, laptop, phone, talks, buffet, junk food causing blockages in gut….endless list of idiotic living …

If we master our Prana, eventually a state comes where you can accurately sense the general vibe of a place or a person without even have a single verbal exchange.


Research


 

IT’S been a tough morning. You were late for work, missed a crucial meeting and now your boss is mad at you. Come lunchtime you walk straight past the salad bar and head for the stodge. You can’t help yourself – at times of stress the brain encourages us to seek out comfort foods. That much is well known. What you probably don’t know, though, is that the real culprit may not be the brain in your skull but your other brain.

Yes, that’s right, your other brain. Your body contains a separate nervous system that is so complex it has been dubbed the second brain. It comprises an estimated 500 million neurons – about five times as many as in the brain of a rat – and is around 9 metres long, stretching from your oesophagus to your anus. It is this brain that could be responsible for your craving under stress for crisps, chocolate and cookies.

Embedded in the wall of the gut, the enteric nervous system (ENS) has long been known to control digestion. Now it seems it also plays an important role in our physical and mental well-being. It can work both independently of and in conjunction with the brain in your head and, although you are not conscious of your gut “thinking”, the ENS helps you sense environmental threats, and then influences your response. “A lot of the information that the gut sends to the brain affects well-being, and doesn’t even come to consciousness,” says Michael Gershon at Columbia-Presbyterian Medical Center, New York.

If you look inside the human body, you can’t fail to notice the brain and its offshoots of nerve cells running along the spinal cord. The ENS, a widely distributed network of neurons spread throughout two layers of gut tissue, is far less obvious, which is why it wasn’t discovered until the mid-19th century. It is part of the autonomic nervous system, the network of peripheral nerves that control visceral functions. It is also the original nervous system, emerging in the first vertebrates over 500 million years ago and becoming more complex as vertebrates evolved – possibly even giving rise to the brain itself.

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Digestion is a complicated business, so it makes sense to have a dedicated network of nerves to oversee it. As well as controlling the mechanical mixing of food in the stomach and coordinating muscle contractions to move it through the gut, the ENS also maintains the biochemical environment within different sections of the gut, keeping them at the correct pH and chemical composition needed for digestive enzymes to do their job.

But there is another reason the ENS needs so many neurons: eating is fraught with danger. Like the skin, the gut must stop potentially dangerous invaders, such as bacteria and viruses, from getting inside the body. If a pathogen should cross the gut lining, immune cells in the gut wall secrete inflammatory substances including histamine, which are detected by neurons in the ENS. The gut brain then either triggers diarrhoea or alerts the brain in the head, which may decide to initiate vomiting, or both.

You needn’t be a gastroenterologist to be aware of these gut reactions – or indeed the more subtle feelings in your stomach that accompany emotions such as excitement, fear and stress. For hundreds of years, people have believed that the gut interacts with the brain to influence health and disease. Yet this connection has only been studied over the last century. Two pioneers in this field were American physician Byron Robinson, who in 1907 published The Abdominal and Pelvic Brain, and his contemporary, British physiologist Johannis Langley, who coined the term “enteric nervous system”. Around this time, it also became clear that the ENS can act autonomously, with the discovery that if the main connection with the brain – the vagus nerve – is severed the ENS remains capable of coordinating digestion. Despite these discoveries, interest in the gut brain fell until the 1990s when the field of neurogastroenterology was born.

We now know that the ENS is not just capable of autonomy but also influences the brain. In fact, about 90 per cent of the signals passing along the vagus nerve come not from above, but from the ENS (American Journal of Physiology – Gastrointestinal and Liver Physiology, vol 283, p G1217).

The feel-good factor

The second brain also shares many features with the first. It is made up of various types of neuron, with glial support cells. It has its own version of a blood-brain barrier to keep its physiological environment stable. And it produces a wide range of hormones and around 40 neurotransmitters of the same classes as those found in the brain. In fact, neurons in the gut are thought to generate as much dopamine as those in the head. Intriguingly, about 95 per cent of the serotonin present in the body at any time is in the ENS.

What are these neurotransmitters doing in the gut? In the brain, dopamine is a signalling molecule associated with pleasure and the reward system. It acts as a signalling molecule in the gut too, transmitting messages between neurons that coordinate the contraction of muscles in the colon, for example. Also transmitting signals in the ENS is serotonin – best known as the “feel-good” molecule involved in preventing depression and regulating sleep, appetite and body temperature. But its influence stretches far beyond that. Serotonin produced in the gut gets into the blood, where it is involved in repairing damaged cells in the liver and lungs. It is also important for normal development of the heart, as well as regulating bone density by inhibiting bone formation (Cell, vol 135, p 825).

But what about mood? Obviously the gut brain doesn’t have emotions, but can it influence those that arise in your head? The general consensus is that neurotransmitters produced in the gut cannot get into the brain – although, theoretically, they could enter small regions that lack a blood-brain barrier, including the hypothalamus. Nevertheless, nerve signals sent from the gut to the brain do appear to affect mood. Indeed, research published in 2006 indicates that stimulation of the vagus nerve can be an effective treatment for chronic depression that has failed to respond to other treatments (The British Journal of Psychiatry, vol 189, p 282).

Such gut to brain signals may also explain why fatty foods make us feel good. When ingested, fatty acids are detected by cell receptors in the lining of the gut, which send nerve signals to the brain. This may not be simply to keep it informed of what you have eaten. Brain scans of volunteers given a dose of fatty acids directly into the gut show they had a lower response to pictures and music designed to make them feel sad than those given saline. They also reported feeling only about half as sad as the other group (The Journal of Clinical Investigation, vol 121, p 3094).

There is further evidence of links between the two brains in our response to stress. The feeling of “butterflies” in your stomach is the result of blood being diverted away from it to your muscles as part of the fight or flight response instigated by the brain. However, stress also leads the gut to increase its production of ghrelin, a hormone that, as well as making you feel more hungry, reduces anxiety and depression. Ghrelin stimulates the release of dopamine in the brain both directly, by triggering neurons involved in pleasure and reward pathways, and indirectly by signals transmitted via the vagus nerve.

In our evolutionary past, the stress-busting effect of ghrelin may have been useful, as we would have needed to be calm when we ventured out in search of food, says Jeffrey Zigman at UT Southwestern Medical Center in Dallas, Texas. In 2011, his team reported that mice exposed to chronic stress sought out fatty food, but those that were genetically engineered to be unable to respond to ghrelin did not (The Journal of Clinical Investigation, vol 121, p 2684). Zigman notes that in our modern world, with freely available high-fat food, the result of chronic stress or depression can be chronically elevated ghrelin – and obesity.

Gershon suggests that strong links between our gut and our mental state evolved because a lot of information about our environment comes from our gut. “Remember the inside of your gut is really the outside of your body,” he says. So we can see danger with our eyes, hear it with our ears and detect it in our gut. Pankaj Pasricha, director of the Johns Hopkins Center for Neurogastroenterology in Baltimore, Maryland, points out that without the gut there would be no energy to sustain life. “Its vitality and healthy functioning is so critical that the brain needs to have a direct and intimate connection with the gut,” he says.

But how far can comparisons between the two brains be taken? Most researchers draw the line at memory – Gershon is not one of them. He tells the story of a US army hospital nurse who administered enemas to the paraplegic patients on his ward at 10 o’clock every morning. When he left, his replacement dropped the practice. Nevertheless, at 10 the next morning, everyone on the ward had a bowel movement. This anecdote dates from the 1960s and while Gershon admits that there have been no other reports of gut memory since, he says he remains open to the idea.

Gut instincts

Then there’s decision-making. The concept of a “gut instinct” or “gut reaction” is well established, but in fact those fluttery sensations start with signals coming from the brain – the fight or flight response again. The resulting feeling of anxiety or excitement may affect your decision about whether to do that bungee jump or arrange a second date, but the idea that your second brain has directed the choice is not warranted. The subconscious “gut instinct” does involve the ENS but it is the brain in your head that actually perceives the threat. And as for conscious, logical reasoning, even Gershon accepts that the second brain doesn’t do that. “Religion, poetry, philosophy, politics – that’s all the business of the brain in the head,” he says.

Still, it is becoming apparent that without a healthy, well-developed ENS we face problems far wider than mere indigestion. Pasricha has found that newborn rats whose stomachs are exposed to a mild chemical irritant are more depressed and anxious than other rats, with the symptoms continuing long after the physical damage has healed. This doesn’t happen after other sorts of damage, like skin irritation, he says.

It has also emerged that various constituents of breast milk, including oxytocin, support the development of neurons in the gut (Molecular Nutrition and Food Research, vol 55, p 1592). This might explain why premature babies who are not breastfed are at higher risk of developing diarrhoea and necrotising enterocolitis, in which portions of the bowel become inflamed and die.

Serotonin is also crucial for the proper development of the ENS where, among its many roles, it acts as a growth factor. Serotonin-producing cells develop early on in the ENS, and if this development is affected, the second brain cannot form properly, as Gershon has shown in mutated mice. He believes that a gut infection or extreme stress in a child’s earliest years may have the same effect, and that later in life this could lead to irritable bowel syndrome, a condition characterised by chronic abdominal pain with frequent diarrhoea or constipation that is often accompanied by depression. The idea that irritable bowel syndrome can be caused by the degeneration of neurons in the ENS is lent weight by recent research revealing that 87 out of 100 people with the condition had antibodies in their circulation that were attacking and killing neurons in the gut (Journal of Neurogastroenterology and Motility, vol 18, p 78).

If nothing else, the discovery that problems with the ENS are implicated in all sorts of conditions means the second brain deserves a lot more recognition than it has had in the past. “Its aberrations are responsible for a lot of suffering,” says Pasricha. He believes that a better understanding of the second brain could pay huge dividends in our efforts to control all sorts of conditions, from obesity and diabetes to problems normally associated with the brain such as Alzheimer’s and Parkinson’s. Yet the number of researchers investigating the second brain remains small. “Given it’s potential, it’s astonishing how little attention has been paid to it,” says Pasricha.

Mental illnesses of the gut

A growing realisation that the nervous system in our gut is not just responsible for digestion (see main story) is partly fuelled by discoveries that this “second brain” is implicated in a wide variety of brain disorders. In Parkinson’s disease, for example, the problems with movement and muscle control are caused by a loss of dopamine-producing cells in the brain. However, Heiko Braak at the University of Frankfurt, Germany, has found that the protein clumps that do the damage, called Lewy bodies, also show up in dopamine-producing neurons in the gut. In fact, judging by the distribution of Lewy bodies in people who died of Parkinson’s, Braak thinks it actually starts in the gut, as the result of an environmental trigger such as a virus, and then spreads to the brain via the vagus nerve.

Likewise, the characteristic plaques or tangles found in the brains of people with Alzheimer’s are present in neurons in their guts too. And people with autism are prone to gastrointestinal problems, which are thought to be caused by the same genetic mutation that affects neurons in the brain.

Although we are only just beginning to understand the interactions between the two brains, already the gut offers a window into the pathology of the brain, says Pankaj Pasricha at Johns Hopkins University in Baltimore, Maryland. “We can theoretically use gut biopsies to make early diagnoses, as well as to monitor response to treatments.”

Cells in the second brain could even be used as a treatment themselves. One experimental intervention for neurodegenerative diseases involves transplanting neural stem cells into the brain to replenish lost neurons. Harvesting these cells from the brain or spinal cord is not easy, but now neural stem cells have been found in the gut of human adults (Cell Tissue Research, vol 344, p 217). These could, in theory, be harvested using a simple endoscopic gut biopsy, providing a ready source of neural stem cells. Indeed, Pasricha’s team is now planning to use them to treat diseases including Parkinson’s.

-by Emma Young, New Scientist

Gut Microbes Decides When to Stop Eating

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Even signal to stop EATING comes from our microbe friends! 🙂

Now you know why so many of us are voracious eaters. 🙂 (Lack or faulty microbial alert)

“Twenty minutes after a meal, gut microbes produce proteins that can suppress food intake in animals, reports a study.”

But we eat so fast that before such natural STOP alert is caught by brain, we eat over-capacity! 🙂 And this leads to indigestion, acidity, stomach-ache and all.

Eat slow! Respect microbes! Don’t see enemy in bacteria! See bacteria as your friends! Your guides! Act to maintain healthy GUT!


Research


Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth

Don’t have room for dessert? The bacteria in your gut may be telling you something. Twenty minutes after a meal, gut microbes produce proteins that can suppress food intake in animals, reports a study published November 24 in Cell Metabolism. The researchers also show how these proteins injected into mice and rats act on the brain reducing appetite, suggesting that gut bacteria may help control when and how much we eat.

The new evidence coexists with current models of appetite control, which involve hormones from the gut signalling to brain circuits when we’re hungry or done eating. The bacterial proteins–produced by mutualistic E. coli after they’ve been satiated–were found for the first time to influence the release of gut-brain signals (e.g., GLP-1 and PYY) as well as activate appetite-regulated neurons in the brain.

“There are so many studies now that look at microbiota composition in different pathological conditions but they do not explore the mechanisms behind these associations,” says senior study author Sergueï Fetissov of Rouen University and INSERM’s Nutrition, Gut & Brain Laboratory in France. “Our study shows that bacterial proteins from E. coli can be involved in the same molecular pathways that are used by the body to signal satiety, and now we need to know how an altered gut microbiome can affect this physiology.”

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Mealtime brings an influx of nutrients to the bacteria in your gut. In response, they divide and replace any members lost in the development of stool. The study raises an interesting theory: since gut microbes depend on us for a place to live, it is to their advantage for populations to remain stable. It would make sense, then, if they had a way to communicate to the host when they’re not full, promoting host to ingest nutrients again.

Summary

The composition of gut microbiota has been associated with host metabolic phenotypes, but it is not known if gut bacteria may influence host appetite. Here we show that regular nutrient provision stabilizes exponential growth of E. coli, with the stationary phase occurring 20 min after nutrient supply accompanied by bacterial proteome changes, suggesting involvement of bacterial proteins in host satiety. Indeed, intestinal infusions of E. coli stationary phase proteins increased plasma PYY and their intraperitoneal injections suppressed acutely food intake and activated c-Fos in hypothalamic POMC neurons, while their repeated administrations reduced meal size. ClpB, a bacterial protein mimetic of α-MSH, was upregulated in the E. coli stationary phase, was detected in plasma proportional to ClpB DNA in feces, and stimulated firing rate of hypothalamic POMC neurons. Thus, these data show that bacterial proteins produced after nutrient-induced E. coli growth may signal meal termination. Furthermore, continuous exposure to E. coli proteins may influence long-term meal pattern.

http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00566-5?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413115005665%3Fshowall%3Dtrue

 

 

The Salt Game : Iodine salt with chlorinated tap water creates Toxins

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saltwater

Tata,Reliance and every other Salt Giant in India talks of Iodine in the salts they make. From Doctors, dietitians to Govt of India, everyone go gaga over Iodine salt.

How healthy it is?

As per this report, cooking with Iodine salt and chlorinated tap water creates toxins!

When bhai Rajiv Dixit talked about it and asked to replace Iodine salt with sendha namak (which is our original salt), people made fun of him and ignored him!

Rock salt comes with 80+ minerals! Unlike processed salt by Salt giants!

Now, accept and alter habit!!


Research


Cooking with Chloraminated Water and Salt Could Create Toxic Molecules

Cooking with chloraminated water could put potentially harmful toxins in your food, according to a new study published in Water Research. The study reveals several molecules that are almost completely new to researchers, created by cooking with chloraminated tap water and iodized table salt.

The authors of the study, from the Hong Kong University of Science and Technology and Nanjing University in China, say further studies are needed to find out more about these molecules and their effect, if any, on our health. In the meantime, limiting cooking time and temperature, and cooking with table salt fortified with iodate instead of iodide, could be safest.

Our tap water is disinfected before we drink it or use it in cooking. This is done in several ways, including by adding chlorine or molecules called chloramines that are made using ammonia. These two processes – chlorination and chloramination – have an effect on the chemical make-up of the water.

Chlorine or chloramines in your tap water can react with the iodized table salt you add to your food, creating a kind of acid called hypoiodous acid. This in itself isn’t cause for concern, but the acid can then react with the food and other organic matter in the tap water to create cooking iodinated disinfection byproducts (I-DBPs) – molecules that are almost completely new to researchers. For the new study, the team identified some molecules and tested their toxicity.

“I-DBPs formed during cooking with chloraminated or chlorinated tap water are something new to environmental chemists, toxicologists and engineers,” said Dr. Xiangru Zhang, corresponding author of the paper and Associate Professor at the Hong Kong University of Science and Technology. “They are relevant not only to drinking water researchers and practitioners but also to the public.”

The researchers analysed the I-DBPs formed during cooking with chlorinated and chloraminated tap water. They simulated cooking with different types of tap water at varying temperatures and time, and added wheat flour and iodized salt to see what I-DBPs would be formed.

Using cutting-edge chemistry techniques, they identified 14 completely new molecules and determined the structure of nine molecules. They then carried out tests to see how toxic nine of the molecules are and found that some of the molecules are 50–200 times more toxic than others.

https://www.elsevier.com/about/press-releases/research-and-journals/cooking-with-chloraminated-water-and-salt-could-create-toxic-molecules?sf15916636=1

Identification, toxicity and control of iodinated disinfection byproducts in cooking with simulated chlor(am)inated tap water and iodized table salt

Chlorine/chloramine residuals are maintained in drinking water distribution systems to prevent microbial contamination and microorganism regrowth. During household cooking processes (e.g., soup making), the residual chlorine/chloramines in tap water may react with the iodide in iodized table salt to form hypoiodous acid, which could react with remaining natural organic matter in tap water and organic matter in food to generate iodinated disinfection byproducts (I-DBPs). However, I-DBPs formed during cooking with chloraminated/chlorinated tap water are almost completely new to researchers. In this work, by adopting precursor ion scan of m/z 127 using ultra performance liquid chromatography/electrospray ionization-triple quadrupole mass spectrometry, many new polar I-DBPs formed during cooking with chloraminated/chlorinated tap water were detected and proposed with structures, of which 3-iodo-4-hydroxybenzaldehyde, 3-iodo-4-hydroxybenzoic acid, 3-iodo-4-hydroxy-5-methylbenzoic acid, diiodoacetic acid, 3,5-diiodo-4-hydroxybenzaldehyde, 3,5-diiodo-4-hydroxybenzoic acid, 2,6-diiodo-4-nitrophenol, 2,4-diiodo-6-nitrophenol, and 2,4,6-triiodophenol were confirmed with standard compounds. With the aid of ultra fast liquid chromatography/ion trap-time of flight-mass spectrometry, molecular formula identification of five new I-DBPs (C8H5O4I, C7H4NO4I, C8H5O5I, C7H4NO5I, and C8H6O3I2) was achieved. A developmental toxicity with a recently developed sensitive bioassay was conducted for the newly identified I-DBPs, suggesting that phenolic I-DBPs (except for iodinated carboxyphenols) were about 50–200 times more developmentally toxic than aliphatic I-DBPs. The major I-DBPs in a baseline simulated cooking water sample were determined to be from 0.72 to 7.63 μg/L. Polar I-DBPs formed under various disinfection and cooking conditions were compared, and suggestions for controlling their formation were provided.

http://www.sciencedirect.com/science/article/pii/S0043135415302682?np=y

Deepawali Churning: Pre-requisites for being blessed by Maa Sita

From this Deepawali to next Deepawali, strive to be micro version of Hanuman at least. So that Maa Sita can bless.

Maa's blessings
Maa’s blessings

——————————————————
Pre-requisites for being blessed by माँ सीता
——————————————————
राम: अयोध्या रक्षक, सीता पति
अयोध्या : ह्रदय
हनुमान : प्राण
सीता: कुण्डलिनी
लंका : मूलाधार
At the end of the war, Ram accepts the seat @ अयोध्या. The citizens of Ayodhya host flags on every house. Rama returns to his paternal palace in Ayodhya. Sugreeva orders four of his monkeys to bring water from four oceans in jars given to them. Some monkeys brought water from five hundred rivers, as also from the four oceans for the purpose of the ceremony. Vasishta along with other brahmins as priests caused Rama to be consecrated with that water. The virgins, ministers, warriors, merchants, the four gods as well as other gods sprinkled sap of all kinds of herbs on Rama. Vasishta and other priests officiating the coronation-ceremony adorned Rama with an auspicious and charming crown. Then, Rama gives away presents to the priests as well as Sugreeva and Angada. Rama presents a pearl-necklace to Seetha and Seetha presents that necklace in turn to Hanuman.

How to identify the Hanuman, the Bhakt, the Sadhak of Maa?

तामिङ्गितज्ञः सम्प्रेक्ष्य बभाषे जनकात्मजाम् |
प्रदेहि सुभगे हारन् यस्य तुष्टासि भामिनि || ६-१२८-८१
तेजो धृतिर्यशो दाक्ष्यं सामर्थ्यं विनयो नयः |
पौरुषन् विक्रमो बुद्धिर्यस्मिन्नेतानि नित्यदा || ६-१२८-८२

Looking at her, Rama who was acquainted with the gesture of another spoke to Seetha as follows: “Dear Seetha! Give the pearl-necklace to a person, with whom you are pleased and in whom the following viz. sharpness, firmness, renown, dexterity, competence, modesty, prudence, virility, prowess and intelligence are ever present.”

Ram is benevolent. He will give away everything based on your capacity. But the gift from Maa is for only Hanuman.

Who is Hanuman?
हनुमान = प्राण that has following present: तेज,धृति,यश,चतुरता,शक्ति,विनय,निति,पुरुषार्थ,पराक्रम,उत्तम बुध्धि

May this Deepawali, you cultivate/revive at least micro version of Hanuman in self! Be प्राणवान! पवनपुत्र हनुमान!साक्षात् अग्नि!

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