GUT

GUT

प्राण, microbes and obesity

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bac

This land is land of मरुत/मारुति/हनुमान/गणेश worshiper. If not 100%, 80% of Indians worship one of them (Hanuman and/or Ganesh).

We do this because, we know the value of मूलाधार (GUT in modern medical science terms). We also know impact of focused mind on the well-being of Body.

Microbes are nothing but loosely-coupled manifestation of प्राण (here प्राण@मूलाधार ) in contrast to body-cells who are tightly coupled as organs.

One more study praising importance of microbes (i.e. प्राण => हनुमान, गणेश, मारुति i.e. driving force behind microbes population protection and control )

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“Obesity is linked to changes in our gut microbes — the trillions of tiny organisms that inhabit our intestines.

“Taken together these experiments demonstrate a causal link between alterations in the gut microbiota in response to changes in the diet and increased acetate production,” said Shulman. The increased acetate in turn leads to increased food intake, setting off a positive feedback loop that drives obesity and insulin resistance, he explained.

The study authors suggest that this positive feedback loop may have served an important role in evolution, by prompting animals to fatten up when they stumbled across calorically dense food in times of food scarcity.


Research


Study reveals how altered gut microbes cause obesity

http://news.yale.edu/2016/06/08/study-reveals-how-altered-gut-microbes-cause-obesity

“Alterations in the gut microbiota are associated with obesity and the metabolic syndrome in both humans and rodents,” Shulman noted. “In this study we provide a novel mechanism to explain this biological phenomenon in rodents, and we are now examining whether this mechanism translates to humans.”

दूषित वात : Transfer of Gut Bacteria Affects Brain Function and Nerve Fiber Insulation

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Transfer of Gut Bacteria Affects Brain Function and Nerve Fiber Insulation
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GutBrain
 
वात is the root cause of many mental disorders. When someone talks about altering or experimenting Microbes, I consider them as वात-प्राण experiments.
 
In one such experiment, it was found that specific combinations of gut bacteria produce substances that affect myelin content and cause social avoidance behaviors in mice.
 
This gives many hints.
 
1) Why August agitations are common across the world (post summer heat monsoon vata prakopa? 🙂 It is easy to instigate mob during seasonal vata prakop. Be it India Against corruption or Egypt or 2011 England riots)
2) Why many teens on junk food are showing anti-social behavior
3) Why cases of sudden suicides are increasing
4) Autism cases
 
Short answer: Disturbed Prana lead to disturbed Vata ==> Mental disorders
 
May Shani Maharaj bless us all and keep us away from mental disorders.
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Research
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Transfer of Gut Bacteria Affects Brain Function and Nerve Fiber Insulation

 
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Abstract:
 
Gene-environment interactions impact the development of neuropsychiatric disorders, but the relative contributions are unclear. Here, we identify gut microbiota as sufficient to induce depressive-like behaviors in genetically distinct mouse strains. Daily gavage of saline in non-obese diabetic (NOD) mice induced a social avoidance behavior that was not observed in C57BL/6 mice. This was not observed in NOD animals with depleted microbiota via oral administration of antibiotics. Transfer of intestinal microbiota, including members of the Clostridiales, Lachnospiraceae and Ruminococcaceae, from vehicle-gavaged NOD donors to microbiota-depleted C57BL/6 recipients was sufficient to induce social avoidance and change gene expression and myelination in the prefrontal cortex. Metabolomic analysis identified increased cresol levels in these mice, and exposure of cultured oligodendrocytes to this metabolite prevented myelin gene expression and differentiation. Our results thus demonstrate that the gut microbiota modifies the synthesis of key metabolites affecting gene expression in the prefrontal cortex, thereby modulating social behavior.
 
http://www.mountsinai.org/about-us/newsroom/press-releases/transfer-of-gut-bacteria-affects-brain-function-and-nerve-fiber-insulation

GUT = Ganesha = Beginning of life

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Various Ganesha forms - varies as per Muladhara

DigestiveFire

I personally do not see body with reductionist perception. However, if I really want to glorify each organ, I would never miss GUT.

The heart and the brain—are generally held in high regard. We see the heart as central to life since it pumps blood around the body. The brain is admired for its ability to create a dazzling array of new mental images and concepts every second. But the gut, in most people’s eyes, is good for little more than going to the toilet.

We must break this world-view. Revering and respecting GUT is first step towards respecting our body and working religiously to serve billion+ body cells.

Educate your child about wonderful working of GUT. Before they are stereotyped to revere brain and heart.

GUT = Ganesha = Beginning of life.

A Link Between Gut Bacteria and Neurogenesis: Mouse Study

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neuron_spike_train_by_neutrix-d3lo9dl-900x450

I shared here many times that प्राण is cellular intelligence and memory. Mar the प्राण, do not retain प्राण and your body cells lose intelligence.

Lost cellular intelligence = Zombie cells = Prone to proliferation, inflammation, retard responses.

Here is the paper in support of this observation.

antibiotics = lack of prana = brain development hampered = memory function impaired.


Research


A Link Between Gut Bacteria and Neurogenesis: Mouse Study

Summary: According to a new mouse study, antibotics that are strong enough to kill gut bacteria can also halt the growth of hippocampal neurons.

Source: Cell Press.

http://neurosciencenews.com/neurogenesis-gut-bacteria-4253/

http://www.cell.com/cell-reports/pdf/S2211-1247(16)30518-6.pdf

Antibiotics strong enough to kill off gut bacteria can also stop the growth of new brain cells in the hippocampus, a section of the brain associated with memory, reports a study in mice published May 19 in Cell Reports. Researchers also uncovered a clue to why– a type of white blood cell seems to act as a communicator between the brain, the immune system, and the gut.

“We found prolonged antibiotic treatment might impact brain function,” says senior author Susanne Asu Wolf of the Max-Delbrueck-Center for Molecular Medicine in Berlin, Germany. “But probiotics and exercise can balance brain plasticity and should be considered as a real treatment option.”

Wolf first saw clues that the immune system could influence the health and growth of brain cells through research into T cells nearly 10 years ago. But there were few studies that found a link from the brain to the immune system and back to the gut.

In the new study, the researchers gave a group of mice enough antibiotics for them to become nearly free of intestinal microbes. Compared to untreated mice, the mice who lost their healthy gut bacteria performed worse in memory tests and showed a loss of neurogenesis (new brain cells) in a section of their hippocampus that typically produces new brain cells throughout an individual’s lifetime. At the same time that the mice experienced memory and neurogenesis loss, the research team detected a lower level of white blood cells (specifically monocytes) marked with Ly6Chi in the brain, blood, and bone marrow. So researchers tested whether it was indeed the Ly6Chi monocytes behind the changes in neurogenesis and memory.

In another experiment, the research team compared untreated mice to mice that had healthy gut bacteria levels but low levels of Ly6Chi either due to genetics or due to treatment with antibodies that target Ly6Chi cells. In both cases, mice with low Ly6Chi levels showed the same memory and neurogenesis deficits as mice in the other experiment who had lost gut bacteria. Furthermore, if the researchers replaced the Ly6Chi levels in mice treated with antibiotics, then memory and neurogenesis improved.

“For us it was impressive to find these Ly6Chi cells that travel from the periphery to the brain, and if there’s something wrong in the microbiome, Ly6Chi acts as a communicating cell,” says Wolf.

Researchers connect brain blood vessel lesions to intestinal bacteria

https://www.ninds.nih.gov/News-Events/News-and-Press-Releases/Press-Releases/Researchers-connect-brain-blood-vessel-lesions

A study in mice and humans suggests that bacteria in the gut can influence the structure of the brain’s blood vessels, and may be responsible for producing malformations that can lead to stroke or epilepsy. The research, published in Nature, adds to an emerging picture that connects intestinal microbes and disorders of the nervous system. The study was funded by the National Institute of Neurological Disorders and Stroke (NINDS), a part of the National Institutes of Health (NIH).

Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled blood vessels that can lead to seizures or stroke when blood leaks into the surrounding brain tissue. A team of scientists at the University of Pennsylvania investigated the mechanisms that cause CCM lesions to form in genetically engineered mice and discovered an unexpected link to bacteria in the gut. When bacteria were eliminated the number of lesions was greatly diminished.

“This study is exciting because it shows that changes within the body can affect the progression of a disorder caused by a genetic mutation,” said Jim I. Koenig, Ph.D., program director at NINDS.

Gut is not Gutter : Your gut bacteria don’t like junk food – even if you do

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Do you like to visit dirty and untidy homes? Do you give the same treatment to your relatives and friends when they visit your home? Do we scold them for coming at wrong time?

GUT is home for billions of bacteria. They stay their to do numerous biological tasks for our well-being. In fact, their population variety decides, what nutrients we can digest and what not. Their population really drives our emotional responses. Richness in their variety is essential.

We rely on our bacteria to produce much of our essential nutrients and vitamins while they rely on us eating plants and fruits to provide them with energy and to produce healthy chemicals which keep our immune system working normally.

We are unlikely to stop people eating fast food, but the devastating effects on our microbes and our long term health could possibly be mitigated if we also eat foods which our microbes love like probiotics (yogurts), root vegetables, nuts, olives and high-fibre foods. What they seem to crave, above all else, is food diversity and a slice of gherkin in the burger just isn’t enough.

When we keep eating junk food, we kill them. We show them the door.

Tim Spector, Professor of Genetic Epidemiology at King’s College London, did an experiment with his own son.

Read to know how junk food destroys GUT population.


Research


Your gut bacteria don’t like junk food – even if you do

https://theconversation.com/your-gut-bacteria-dont-like-junk-food-even-if-you-do-41564

“Tom’s gut had seen massive shifts in his common microbe groups for reasons that are still unclear. Firmicutes were replaced with Bacteroidetes as the dominant type, while friendly bifidobacteria that suppress inflammation halved. However the clearest marker of an unhealthy gut is losing species diversity and after just a few days Tom had lost an estimated 1,400 species – nearly 40% of his total. The changes persisted and even two weeks after the diet his microbes had not recovered. Loss of diversity is a universal signal of ill health in the guts of obese and diabetic people and triggers a range of immunity problems in lab mice.”

Do you take care of Second Brain?

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155_Muladhar
The part of the alimentary canal between the stomach and the anus is known as GUT. This is reservoir of microbes. Critical digestive processes happen here.
 
In Ayurveda, this place is considered as मूलाधार चक्र.गणपति resides here. Ayurveda considers body beyond physical body and energy layer is one of such layer, प्राणमय कोष. Energy @ मूलाधार चक्र is responsible for person’s intelligence, valor and many other traits. And Ganapati resides here. He controls all activities.
155_SecondBRain2 155_SecondBRain
 
Now, modern science says, GUT is our second brain. 🙂 🙂 We use this second brain as gutter. We eat anything and everything. Creating highly polluted environment. So second brain hardly works. 🙂 🙂 😉 😛
 
Moral of the post: Do not make fun of your rituals under the influence of media, TV, Bollywood and some so called rational authors. If you do not understand a bit, still follow your culture. There are ample hidden benefits.
 
When you meditate on मूलाधार by chanting ganapati atharvashirsha, unique mental and physical state emerge. In modern science language, you actually help your second brain to work well.
 
Antibiotics disturbs this area most. This is the reason I advocate alternative use of controlling bacterial infection and not antibiotics. As it directly affect our emotions and thinking capacity.
 
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Read More
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Think Twice: How the Gut’s “Second Brain” Influences Mood and Well-Being

The emerging and surprising view of how the enteric nervous system in our bellies goes far beyond just processing the food we eat

http://www.scientificamerican.com/article/gut-second-brain/

Thus equipped with its own reflexes and senses, the second brain can control gut behavior independently of the brain, Gershon says. We likely evolved this intricate web of nerves to perform digestion and excretion “on site,” rather than remotely from our brains through the middleman of the spinal cord. “The brain in the head doesn’t need to get its hands dirty with the messy business of digestion, which is delegated to the brain in the gut,” Gershon says. He and other researchers explain, however, that the second brain’s complexity likely cannot be interpreted through this process alone.

“The system is way too complicated to have evolved only to make sure things move out of your colon,” says Emeran Mayer, professor of physiology, psychiatry and biobehavioral sciences at the David Geffen School of Medicine at the University of California, Los Angeles (U.C.L.A.). For example, scientists were shocked to learn that about 90 percent of the fibers in the primary visceral nerve, the vagus, carry information from the gut to the brain and not the other way around. “Some of that info is decidedly unpleasant,” Gershon says.

The second brain informs our state of mind in other more obscure ways, as well. “A big part of our emotions are probably influenced by the nerves in our gut,” Mayer says. Butterflies in the stomach—signaling in the gut as part of our physiological stress response, Gershon says—is but one example. Although gastrointestinal (GI) turmoil can sour one’s moods, everyday emotional well-being may rely on messages from the brain below to the brain above. For example, electrical stimulation of the vagus nerve—a useful treatment for depression—may mimic these signals, Gershon says.

AN ANCIENT SYMBIOSIS : Mother’s milk and Prana(microbes)

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Fig4_MicrobirthBreastvBottle5

Medical science can try N-efforts but they cannot create formula that can compete with mother’s milk.

Mothers’ milk guides the development of neonates’ gut microbiota, nourishing a very specific bacterial population that protects the child. Now a team of researchers has identified the compound in the milk that supplies this nourishment, and has shown that it can be obtained from cow’s milk, which could result in using cow’s milk as a prebiotic for infants.

If you are lactating mother, do not compromise.(Y). Do your best so that your child gets invaluable boons.

On the same note, without torturing Gau mata, receive her prasad for daily प्राणपूर्ति.

जीवनके श्री गणेश (GUT Mircrobial protection) माताही (Breastfeeding) करती है|


Research


MOTHERS’ MILK AND THE INFANT GUT MICROBIOTA: AN ANCIENT SYMBIOSIS

https://www.asm.org/index.php/journal-press-releases/94134-mothers-milk-and-the-infant-gut-microbiota-an-ancient-symbiosis

Nursing infants’ gastrointestinal tracts are enriched with specific protective microbes. Mother’s milk, itself, guides the development of neonates’ gut microbiota, nourishing a very specific bacterial population that, in turn, provides nourishment and protects the child. Now a team from the University of California, Davis, has identified the compound in the milk that supplies this nourishment, and has shown that it can be obtained from cow’s milk. This work could result in using cow’s milk to provide that compound as a prebiotic for infants. The research is published ahead of print on April 15th in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.
In earlier research, these investigators, led by David A. Mills, PhD, had shown that glycoproteins from milk, which contain both protein, and molecules containing multiple sugars, called oligosaccharides, were the source of that nourishment. They also had found that the infant-associated subspecies of the bacterium, Bifidobacterium longum subsp. infantis (B. infantis), produced an enzyme that could cleave the oligosaccharides from the milk glycoproteins, and they had identified that enzyme.
For the current study, Mills, who is Professor and Shields Endowed Chair in Dairy Food Science, and his collaborators posited that these oligosaccharides were the food source for B. infantis. They then showed that the enzyme could break down glycoproteins not only from mother’s milk, but from cow’s milk, releasing the oligosaccharides.
“The released oligosaccharides turned out to be an incredible substrate for B. infantis’ growth,” said Mills. At the same time, Mills et al. showed that the oligosaccharides did not nourish adult-associated bifidobacteria.
All that suggests that getting the bioactive oligosaccharides into infant formula could improve it, said Mills. But his emphasis is on the science, he said. “The amazing thing to me is how selective these released oligosaccharides are as a substrate for growth.”
Mills noted that B. infantis has many genes involved in breaking down glycoproteins in mother’s milk in order to release the oligosaccharides. Mother’s milk coevolved over millions of years with mammals, and with their beneficial gut microbiota that it helped to thrive. “It is the only food that co-evolved with humans to make us healthy,” said Mills.

Oligosaccharides released from milk glycoproteins are selective growth substrates for infant-associated bifidobacteria

http://aem.asm.org/content/early/2016/03/28/AEM.00547-16.abstract

Milk, in addition to nourishing the neonate, provides a range of complex glycans whose construction ensures a specific enrichment of key members of the gut microbiota in the nursing infant, a consortium known as the milk-oriented microbiome. Milk glycoproteins are thought to function similarly, as specific growth substrates for bifidobacteria common to the breast fed infant gut. Recently, a cell wall-associated endo-β-N-acetylglucosaminidase (EndoBI-1) found in various infant-borne bifidobacteria was shown to remove a range of intact N-linked glycans. We hypothesized that these released oligosaccharide structures can serve as a sole source for the selective growth of bifidobacteria. Here, EndoBI-1 was used to release these N-glycans from concentrated bovine colostrum at the pilot scale. EndoBI-1-released N-glycans supported the rapid growth of Bifidobacterium longum subsp. infantis, a species that grows well on human milk oligosaccharides, but did not support growth of Bifidobacterium animalis subsp. lactis, a species which does not. Conversely Bifidobacterium longum subsp. infantis ATCC 15697 did not grow on the deglycosylated milk protein fraction clearly demonstrating that the glycan portion of milk glycoproteins provides the key substrate for growth. Mass spectrometry-based profiling revealed that B.longum subsp. infantis consumed 73% of neutral and 92% of sialylated N-glycans, while B. animalis subsp. lactis only degraded 11% of neutral and virtually no (<1%) sialylated N-glycans. These results provide mechanistic support that N-linked glycoproteins from milk serve as selective substrates for the enrichment of infant-borne bifidobacteria capable of carrying out the initial deglycosylation. Moreover, released N-glycans are better growth substrates than the intact milk glycoproteins suggesting that EndoBI-1 cleavage is a key initial step in consumption of glycoproteins. Finally, the variety of N-glycans released from bovine milk glycoproteins suggests they may serve as novel prebiotic substrates with selective properties similar to those of human milk oligosaccharides.

 

Prana heals : UCLA research suggests that Gut Microbes Prevents Cancer

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But we eat mindless acidic food so that bacteria can hardly reach GUT via digestive track.
We kill mouth bacteria by using toothpaste.
We kill them by handwash and soaps.
We hardly spend physically active time under the sun.
Our food lack supporting nutrition so that bacteria can travel and stabilize at Gut.
Mindless usage of antibiotics.
 
And then we are shocked by sudden increase in cancer cases! 😉
 
As a society, unless we correct our priorities, we will celebrate Cancer hospitals as human success milestones. 😛 😀
Microbes = Prana
Prana is an ultimate healer.
mirror daily_b39500c1cb938cbba99dc02f3fed73fd
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Research
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UCLA research suggests that gut bacteria could help prevent cancer

https://www.uclahealth.org/news/ucla-research-suggests-that-gut-bacteria-could-help-prevent-cancer

“It is not invasive and rather easy to do,” he said.

Over millions of years, gut bacteria have evolved into both good and bad types: The good ones have anti-inflammatory properties and the bad ones promote inflammation. The human body typically contains about 10 trillion bacterial cells, compared with only 1 trillion human cells.

Schiestl and his colleagues isolated a bacterium called Lactobacillus johnsonii 456, which is the most abundant of the beneficial bacteria, and which has some pretty useful applications outside of medicine. “Since it is a Lactobacillus strain, it makes excellent yogurt, kefir, kombucha and sauerkraut.”

In the UCLA study the bacterium reduced gene damage and significantly reduced inflammation — a critical goal because inflammation plays a key role in many diseases, including cancer, neurodegenerative diseases, heart disease, arthritis and lupus, and in the aging process.

Previous research led by Schiestl presented the first evidence of a relationship between intestinal microbiota and the onset of lymphoma, a cancer that originates in the immune system. The new study explains how this microbiota might delay the onset of cancer, and suggests that probiotic supplements could help keep cancer from forming.

For both studies, Schiestl and his team used mice that had mutations in a gene called ATM, which made them susceptible to a neurologic disorder called ataxia telangiectasia. The disorder, which affects 1 in 100,000 people, is associated with a high incidence of leukemia, lymphomas and other cancers.

The mice were divided into two groups — one that was given only anti-inflammatory bacteria and the other that received a mix of inflammatory and anti-inflammatory microbes that typically co-exist in the intestines.

In the Cancer Research paper, Schiestl and his team showed that in the mice with more of the beneficial bacteria, the lymphoma took significantly longer to form.

In the new study, the researchers analyzed the metabolites — molecules produced by the gut’s natural metabolic action — in the mice’s urine and feces. The scientists were surprised to find that the mice that were receiving only the beneficial microbiota produced metabolites that are known to prevent cancer. Those mice also had more efficient fat and oxidative metabolism, which the researchers believe might also lower the risk for cancer.

Among the other results, in the mice receiving only the good bacteria, lymphoma formed only half as quickly as it did in the other mice. In addition, mice with the good bacteria lived four times longer and had less DNA damage and inflammation.

Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis

Abstract

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151190

Intestinal microbiota play a significant role in nutrient metabolism, modulation of the immune system, obesity, and possibly in carcinogenesis, although the underlying mechanisms resulting in disease or impacts on longevity caused by different intestinal microbiota are mostly unknown. Herein we use isogenic Atm-deficient and wild type mice as models to interrogate changes in the metabolic profiles of urine and feces of these mice, which are differing in their intestinal microbiota. Using high resolution mass spectrometry approach we show that the composition of intestinal microbiota modulates specific metabolic perturbations resulting in a possible alleviation of a glycolytic phenotype. Metabolites including 3-methylbutyrolactone, kyneurenic acid and 3-methyladenine known to be onco-protective are elevated in Atm-deficient and wild type mice with restricted intestinal microbiota. Thus our approach has broad applicability to study the direct influence of gut microbiome on host metabolism and resultant phenotype. These results for the first time suggest a possible correlation of metabolic alterations and carcinogenesis, modulated by intestinal microbiota in A-T mice.

Immune System Fosters Good Bacteria

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We have been taught that immune system means Army. Immune System is defense system. But we were never taught that the immune system does more than mere purging non-body particles out of body.

Here is the interesting finding which supports what we discussed on this subject recently:
“When the immune system functions properly (MyD88 is active, green), IgA antibodies bind multiple species of bacteria, keeping the numbers and types of ‘good’ bacteria that inhabit the gut under control. (Right) When the immune system is disrupted (MyD88 is inactive, gray), IgA binds bacteria less effectively, and the bacterial community becomes imbalanced, jeopardizing digestive health.”

If bacteria are enemy, why would immune system help them grow? 🙂

There is no enmity with Mother Nature as most brainwashing media tell you. There is no war against bacteria or Virus going on. Purpose of immune system is to maintain your existence. That is it.

The ability of the human body to live in peace with 10 microbes per every human cell is a state of genuine immunity, wherein the body exercises a holy indifference to the resident microbes, to gain therefrom freedom from any reactivity against the obviously non-self microbes.

This is ability to realize self and non-self can be best developed when a child is exposed more often to mother nature.

Stop this delusion of war against the nature and see the magic. Your life will be much more healthier then the past! Try it! (Y)

Tulsi, Turmeric, Ghee (Desi Gau’s), Honey (Pure jungle based), Milk (Desi gau’s raw) – they all help you too strengthen immune system i.e. your own identity so that your body can identify self from non-self! 🙂


Research


http://healthcare.utah.edu/publicaffairs/news/2015/01/01-22-15_Immune_System_Fosters_Good_Bacteria.php

Immune System Promotes Digestive Health by Fostering Community of “Good” Gut Bacteria

As many as 1.4 million Americans suffer from uncomfortable abdominal cramping and diarrhea that come with ulcerative colitis and Crohn’s disease. These conditions, collectively known as inflammatory bowel disease (IBD), are associated with an imbalance among the thousands of species of “good” bacteria that inhabit the gut. A University of Utah study published on Jan. 22, 2015, in Cell Host and Microbe demonstrates that mice deficient for a component of the immune system, a protein called MyD88, have an imbalanced gut bacterial community – with some species dominating over others – and are more susceptible to contracting a severe IBD-like illness. Further, fecal transplants from healthy donors alleviate IBD symptoms in these mice.

The results show that the immune system encourages growth of a healthy community of “good” bacteria that is important for digestive health. This perspective on immune system function is in contrast to it’s best-known role as the first line of defense in the fight against pathogens, including invasive bacteria.

“Our work highlights that the immune system shapes the composition of bacterial communities in the intestine,” says senior author June Round, Ph.D., assistant professor of pathology at the University of Utah School of Medicine. “This interaction is important because it’s becoming more and more clear that resident microbes are very important for our health.”

Considering that some people with IBD have mutations in genes that are part of a MyD88-controlled pathway, fecal transplantation – which involves collecting and processing stool from a healthy donor, and delivering it into a recipient’s gut – might help to ameliorate disease in these people, according to Round.

Loss of MyD88 disturbs the microbial community because it disrupts production of IgA. This class of antibody works like a gatekeeper that controls which types of bacteria, and how many, are allowed to inhabit the gut. By performing inventories of total gut bacteria compared to species that bind IgA, the scientists determined that without MyD88, IgA failed to recognize species that it can otherwise.

Children and Hospital Stay (Avoid) : Gut Microbes

topic-NICU-and-Special-Care-Nursery-629x299

30% of US children are now delivered at home or at small facilities. They have started realizing costly side-effects of hospital birth.

In our local villages practices, there is no mass-assembly like place for newborns and infants. Instead, they (mother, infant and caretaker – just three) live in highly customized सूतिका गृह for 1 to 3 to 6 months. No issue like what is mentioned in this article.

There are specifications mentioned in Ayurvedic Samhitas about architecture and facilities for सूतिका गृह. It demands research efforts from us.

गौ-गोबर,घी,दही,मूत्र,दूध – without them, it is difficult to build healthy and life-enriching सूतिका गृह

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On the other hand, we have cruel practices glorified.

The antibiotics given to many killed mother’s bacteria, and bacteria in NICU took over

“Babies typically get their gut bacteria from their mothers during childbirth. Premature infants, however, receive antibiotics during their first week of life to prevent infections, and these antibiotics eliminate many of the microbes the infants receive from their mothers.

As a result, microbes from the NICU colonize the digestive tracts of premature infants, the University of California, Berkeley, researchers found.”

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This is the reason we don’t expose kids to strangers and strange places in their initial years. It is not about infection but mental and प्राणिक exposure to non-compitable humans and places. This is the reason, for first 6 months, don’t expose infants to unknown strangers. Only mother, mother’s mother and father. And grand-parents.


Research


Gut Bacteria in Preemies Altered by Hospital Stay, Study Finds

The antibiotics given to many killed mother’s bacteria, and bacteria in NICU took over

Gut bacteria in premature infants don’t come from their mothers, but from microbes in the neonatal intensive-care unit (NICU), a new study finds.

Babies typically get their gut bacteria from their mothers during childbirth. Premature infants, however, receive antibiotics during their first week of life to prevent infections, and these antibiotics eliminate many of the microbes the infants receive from their mothers.

As a result, microbes from the NICU colonize the digestive tracts of premature infants, the University of California, Berkeley, researchers found.

The researchers swabbed the most-touched surfaces in an NICU and collected fecal samples from two premature infants in the unit. The surfaces checked for microbes included the sink; feeding and breathing tubes; the hands of health workers and parents; incubator access knobs; and keyboards, cell phones and other electronic equipment at the nurses’ station.

The researchers found that the gut bacteria in the two infants were similar to those found on the surfaces in the intensive-care unit. The most abundant types of gut bacteria in the infants were similar to those found on feeding and breathing tubes.

The study was published recently in the journal Microbiome.

“The most common species found in our study — Enterococcus faecalis, Staphylococcus epidermidis, Escherichia coli and Bacteroides fragilis — all have been associated with disease in preterm infants, but can also be commonly isolated from healthy infants and adults,” study author Brandon Brooks said in a journal news release.

“The strains found here are largely opportunistic, lacking many of the really nasty genes found in ‘outbreak’ versions of their respective strains,” Brooks said. “The bacteria would need to be further tested to fully understand [any potential threat].”

Both infants in the study were healthy when they left the hospital.

https://consumer.healthday.com/caregiving-information-6/hospital-news-393/gut-bacteria-in-preemies-altered-by-hospital-stay-study-finds-684245.html

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