Diet

Diet

Universal diet is a myth

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Universal diets don’t work because ‘healthy’ foods differ by individual
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Diet
Globalization is a deepest myth propagated in last 100 years.
Modern medicine is flavor of it.

Even Today, Indian doctors quote British Journal, American Journal and treat patients! What a slavery!

From food to medicine, everything is local in reality. Not only local, personal! Individual!

This is the base on Ayurveda and they call it primitive guess work! What a foolish arrogance modern doctors have!

If two persons with fever visit genuine Ayurvedacharya, both gets different treatment! Unlike idiotic modern medicine! One pill for everyone!

Not only that, food choices changes based on person’s mental state, biological age, season, time of the day, terrain, region and community!

What do we have now?

Pizza for Navratri! Pizza for Diwali! Pizza for Uttrayan! 😀

Replace pizza with any global choice!

We now don’t decide food based on mental state, biological age, season, time of the day, terrain, region and community but what the market bombard on us! Pity!


Research


http://www.cell.com/cell/abstract/S0092-8674(15)01481-6

Personalized Nutrition by Prediction of Glycemic Responses

“Elevated postprandial blood glucose levels constitute a global epidemic and a major risk factor for prediabetes and type II diabetes, but existing dietary methods for controlling them have limited efficacy. Here, we continuously monitored week-long glucose levels in an 800-person cohort, measured responses to 46,898 meals, and found high variability in the response to identical meals, suggesting that universal dietary recommendations may have limited utility. We devised a machine-learning algorithm that integrates blood parameters, dietary habits, anthropometrics, physical activity, and gut microbiota measured in this cohort and showed that it accurately predicts personalized postprandial glycemic response to real-life meals. We validated these predictions in an independent 100-person cohort. Finally, a blinded randomized controlled dietary intervention based on this algorithm resulted in significantly lower postprandial responses and consistent alterations to gut microbiota configuration. Together, our results suggest that personalized diets may successfully modify elevated postprandial blood glucose and its metabolic consequences.”

Why only selective few develop Life-threatening Dengue?

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virus

We modern humans often play petty blame game. It has become our habit to blame insects for our faulty life style!

It is true that Dengue is vector borne sickness. It is also true that certain protein in specific mosquito flag off the onset of dengue and other post-monsoon sicknesses. It is also reality that not all are afflicted by fever when mosquito bites!

What we see as Dengue epidemic, used to be Plague epidemic half a century back. Epidemics are natural and will happen time to time. It is natural way of population control.

During this sensitive time, it is our job to change diet as per season! Increase intake of certain diet and decrease/stop other as per season!

How do you feel when you see pictures from artificial famine of 1940s Bengal?

Disgusting right? Undercurrent of anger pass through entire body, resulted in shivering.

Our body cells go through similar famine trauma when we eat food (fast food, junk food, pesticide food) like morons, when we take unnecessary mental stress, when we indulge in sensual habits like animals. And that too during monsoon!

We are Churchill (who planned artificial famine in Bengal) for our body. On one hand we oppose subjugation by British and on the other hand, we blissfully enjoy same subjugation with own body! Worse breed of hypocrites? Yes, अनार्य, म्लेच्छा.

Roots of dengue or any viral infections are sown way back when we hamper our digestion. When we eat mindlessly against our prakriti, season and capacity of digestive fire (जठराग्नि).

It is actually a पित्त प्रकोप.

Here is the interesting research discussion why only selective few develop life-threatening dengue? It shows that the root is in the blood (पित्त) and not the vector transferred by mosquito!


Research


Discovery helps explain why only some people develop life-threatening dengue infections

Discovery helps explain why only some people develop life-threatening dengue infections

 

IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity

 

http://science.sciencemag.org/content/355/6323/395

A rare ability to enhance dengue virus disease

In some cases, secondary infections of dengue virus can be extremely serious and result in plasma leakage, thrombocytopenia, and hemorrhagic disease. This phenomenon has been attributed to antibody-dependent enhancement. Wang et al. show that a specific subclass of antibody, IgG1, which lacks fucosyl residues on the Fc segment of the heavy chain of the immunoglobulin, is elevated in patients with severe secondary dengue disease. These non-neutralizing antibodies bind activating Fc receptors and appear to cross-react with platelet antigens to cause platelet depletion, contributing to thrombocytopenia.

Abstract

Dengue virus (DENV) infection in the presence of reactive, non-neutralizing immunoglobulin G (IgG) (RNNIg) is the greatest risk factor for dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Progression to DHF/DSS is attributed to antibody-dependent enhancement (ADE); however, because only a fraction of infections occurring in the presence of RNNIg advance to DHF/DSS, the presence of RNNIg alone cannot account for disease severity. We discovered that DHF/DSS patients respond to infection by producing IgGs with enhanced affinity for the activating Fc receptor FcγRIIIA due to afucosylated Fc glycans and IgG1 subclass. RNNIg enriched for afucosylated IgG1 triggered platelet reduction in vivo and was a significant risk factor for thrombocytopenia. Thus, therapeutics and vaccines restricting production of afucosylated, IgG1 RNNIg during infection may prevent ADE of DENV disease.

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