If I say, “using cow antibodies as टीका is ancient practice of this land.”, most of educated Indians will runaway by mocking it ! 🙂
Well, that is the response of brainwashing done by modern education. I don’t pass this as blanket judgement. I can show you many examples with documentary proofs which will reiterate my firm belief about highly advanced society of Bharat.
Here is one more from the field of medical science.
Our text books teach us that smallpox vaccine was invented by Edward Jenner in 1798.
Then how come Dr. J. Z. Holwell, M.D., F.R.S. recorded common practice of small pox Vaccination across Bharat in 1767?
See, this level of brainwashing happens by school text books. And once a firm belief is imprinted in your kid’s mind that ‘Everything Indians is primitive and in inventions happen only in Europe’, you cannot stop them surrendering to the system designed to keep them slaves. And slaves cannot innovate genuinely. 🙂
MUST READ: http://www.reformation.org/holwell.html
“Holwell claimed that when the inoculation regime was strictly followed, it is next to a miracle to hear that it ‘failed in one in a million’. He added that since “this practice of the East has been followed without variation, and with uniform success from the remotest known times, it is but justice to conclude, it must have been originally founded on the basis of rational principles and experiment.”
A doctor publishes paper on Smallpox in 1767 and Edward Jenner inventing it in 1798 – mere coincidence? 😀
Just for you to observe: Traditional Cow shepherd community’s children relatively more healthier then rest.
Do you know reason?
Their affinity with mother Gau. Mother’s teats is breeding ground for harmless but essential viruses (including smallpox). When kids are playing with calf and gau, they go exposed to them early in age which naturally help them build immunity.
In Ancient Gurukul system, when child is admitted to school, he has to serve in Gau shala. Needless to mention reason i.e. to build their immunity 🙂
I have also seen in some community where dermal kit is prepared from dung and urine of cow using black thread and cloth and is tied on shoulder of the newborn. This also works as vaccination like modern days dermal hormone therapies.
But now our so called scholar movie script writers tell us that worshiping cows is wrong number 😀
I don’t ask you to blindly accepting what I am sharing. Do your independent study and you will find the same facts I am finding. (y) 🙂
COW ANTIBODIES YIELD IMPORTANT CLUES FOR DEVELOPING A BROADLY EFFECTIVE AIDS VACCINE
“One approach to a preventive HIV vaccine involves trying to elicit broadly neutralizing antibodies in healthy people, but so far the experiments have been unsuccessful, in both human and animal studies,” said Sok, the study’s first author. “This experiment demonstrates that not only is it possible to produce these antibodies in animals, but we can do so reliably, quickly, and using a relatively simple immunization strategy when given in the right setting.”
All four cows immunized with BG505 SOSIP elicited bnAbs to HIV within 35-52 days. In comparison, it takes HIV-positive humans multiple years to develop comparable responses, and only 5-15% even develop them at all.
Cows cannot be infected with HIV, of course. But these findings illuminate a new goal for HIV vaccine researchers: by increasing the number of human antibodies with long loops, we might have an easier chance of eliciting protective bnAbs by vaccination.
There is no doubt that cows’ ability to produce bNAbs against a complicated pathogen like HIV in a matter of weeks, highlights even broader significance, particularly for emerging pathogens.
“Scientific innovations like this are what propel the field forward,” said IAVI CEO Mark Feinberg. “This surprising set of results warrants further exploration and has potential applications not only to HIV prevention and treatment, but to the rapid development of antibodies and vaccines against other infectious diseases.”
Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows
No immunogen to date has reliably elicited broadly neutralizing antibodies to HIV in humans or animal models. Advances in the design of immunogens (BG505 SOSIP) that antigenically mimic the HIV envelope glycoprotein (Env)1 have improved the elicitation of potent isolate-specific antibody responses in rabbits2 and macaques3, but so far failed to induce broadly neutralizing antibodies. One possible contributor to this failure is that the relevant antibody repertoires are poorly suited to target somewhat occluded conserved epitope regions on Env relative to exposed variable epitopes. To test this hypothesis, we immunized four cows with BG505 SOSIP. The antibody repertoire of cows contains long third heavy chain complementarity determining regions (HCDR3) with an ultralong subset that can reach over 70 amino acids in length4–9. Remarkably, BG505 SOSIP immunization resulted in rapid elicitation of broad and potent serum antibody responses in all four cows. Longitudinal serum analysis for one cow showed the development of neutralization breadth (20%, n = 117 cross-clade isolates) in 42 days and 96% breadth (n = 117) at 381 days. A monoclonal antibody isolated from this cow harboured an ultralong HCDR3 of 60 amino acids and neutralized 72% of cross-clade isolates (n = 117) with a potent median IC50value of 0.028 μg ml−1. We note that breadth was elicited with a single trimer immunogen and did not require additional envelope diversity. Immunization of cows may provide an avenue to rapidly generate antibody prophylactics and therapeutics to address disease agents that have evolved to avoid human antibody responses.