Transfer of Gut Bacteria Affects Brain Function and Nerve Fiber Insulation
वात is the root cause of many mental disorders. When someone talks about altering or experimenting Microbes, I consider them as वात-प्राण experiments.
In one such experiment, it was found that specific combinations of gut bacteria produce substances that affect myelin content and cause social avoidance behaviors in mice.
This gives many hints.
1) Why August agitations are common across the world (post summer heat monsoon vata prakopa? 🙂 It is easy to instigate mob during seasonal vata prakop. Be it India Against corruption or Egypt or 2011 England riots)
2) Why many teens on junk food are showing anti-social behavior
3) Why cases of sudden suicides are increasing
4) Autism cases
Short answer: Disturbed Prana lead to disturbed Vata ==> Mental disorders
May Shani Maharaj bless us all and keep us away from mental disorders.

Transfer of Gut Bacteria Affects Brain Function and Nerve Fiber Insulation

Gene-environment interactions impact the development of neuropsychiatric disorders, but the relative contributions are unclear. Here, we identify gut microbiota as sufficient to induce depressive-like behaviors in genetically distinct mouse strains. Daily gavage of saline in non-obese diabetic (NOD) mice induced a social avoidance behavior that was not observed in C57BL/6 mice. This was not observed in NOD animals with depleted microbiota via oral administration of antibiotics. Transfer of intestinal microbiota, including members of the Clostridiales, Lachnospiraceae and Ruminococcaceae, from vehicle-gavaged NOD donors to microbiota-depleted C57BL/6 recipients was sufficient to induce social avoidance and change gene expression and myelination in the prefrontal cortex. Metabolomic analysis identified increased cresol levels in these mice, and exposure of cultured oligodendrocytes to this metabolite prevented myelin gene expression and differentiation. Our results thus demonstrate that the gut microbiota modifies the synthesis of key metabolites affecting gene expression in the prefrontal cortex, thereby modulating social behavior.